Prevalence of Bacteroides forsythus, Porphyromonas gingivalis and Actinobacillus actinomycetemcomitans in subgingival microflora of Japanese patients with adult and rapidly progressive periodontitis

Abstract

The prevalence and the proportion of B. forsythus and P. gingivalis were significantly correlated with clinical parameters, suggesting that B. forsythus and P. gingivalis are closely related to AP and RPP in the Japanese population.

Loss of adherence ability to human gingival epithelial cells in S-layer protein-deficient mutants of Tannerella forsythensis

“…Several studies reported that major high molecular mass proteins larger than 200 kDa were characteristic of T. forsythensis (Kerosuo, 1988;Gersdorf et al, 1993). We have shown by immunoelectron microscopy that the S-layer is composed of 230 and 270 kDa major proteins (Higuchi et al, 2000;Moriguchi et al, 2003). These S-layer proteins were shown to be specifically recognized by sera from patients with periodontitis (Yoneda et al, 2003).…”

“…Recent studies have suggested an aetiological role of this organism in several forms of periodontal disease (Gersdorf et al, 1993;Takemoto et al, 1997;Haffajee et al, 1998;Yano-Higuchi et al, 2000), periradicular lesion (Gonçalves & Mouton, 1999;Siqueira & Rô ças, 2003) and systemic disease (Noack et al, 2001;Hajishengallis et al, 2002).…”

“…After peptide conjugation to thyroglobulin using m-maleimidobenzoyl-N-hydroxysuccinimide ester (Pierce Biotechnology), as described in the company's instructions, each peptide was emulsified with complete Freund's adjuvant and injected into rabbits subcutaneously four times at 2-week intervals. Specific antisera that reacted to both the 230 and 270 kDa proteins of T. forsythensis were prepared as described previously (Higuchi et al, 2000).…”

Doença periodontal em portadoras de valvopatia durante a gravidez: estudo clínico e microbiológico

“…Of this spectrum, possibly 10 to 20 species participate in the pathogenicity and periodontal destruction in periodontal disease 19 , with a prevalence of gram-negative anaerobic bacilli and among them, A. actinomycetemcomitans (Hacek group), P. gingivalis and P. intermedia, with a predominance in gingival samples 20 .…”

Mechanisms of Periodontitis - Induced Atherosclerosis

“…[41][42][43][44] Although many factors may influence the onset of periodontitis, periodontopathogen bacteria play a key role in the onset and severity of periodontal diseases. [42,45,46] PG is an anaerob obligat, [47] non-motile, [48] pleiomorphic bacteria, and posses a capsul. [49] PG shows a strong proteolitic activity, grows in anaerobic environment, and shows dark pigmentation (brown, dark green, or black) on blood agar.…”