Prevalence of hypomagnesaemia and its correlation with insulin resistance and glycemic status in patients with type 2 dm

Dalai, Siba Prasad; Meher, Lalit Kumar; Hui, Pankaj Kumar; Panda, Sibasish

doi:10.24327/ijcar.2017.3443.0288

Cited by 1 publication

(4 citation statements)

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“…In the present study the mean body mass index (BMI) was 24.33 ± 2.73 kg/M 2 in diabetic group and 24.49 ± 2.21 kg/M 2 in non-diabetic group; difference was not significant (p=0.741). This result correlated with Dalai et al 9 which reported that mean body mass index (BMI) was 23.17 ± 4.78 kg/M 2 in diabetic group and 22.46 ± 3.63 kg/M 2 in non-diabetic group; difference was not significant (p=0.313).…”

Section: Discussionsupporting

confidence: 88%

“…Several others studies also supported this result. 12,26 But Dalai et al 9 found that no significant difference in rates of hypomagnesaemia between diabetic patients and controls (20% and 16% respectively) (p=1.0). Ruhul-Kabir et al 13 also found that hypomagnesaemia was more in diabetics (26.2%) compared to non-diabetic groups (12.3%) but did not differ significantly (p=074).…”

Section: Discussionmentioning

confidence: 96%

“…10 Numerous studies have shown lower serum magnesium concentrations in Type 2 diabetic patients compared to healthy controls. 7,9,11,12 On the contrary, a study in Bangladesh, Ruhul-Kabir et al 13 observed a higher frequency of hypomagnesaemia in the T2DM group than the control group though the difference failed to reach the level of statistical significance (p=0.074). They also found no significant difference in serum Mg levels between the two groups (p=0.582).…”

Section: Original Article Original Article Original Article Original ...mentioning

confidence: 95%

“…The amount of urine magnesium wasting is decreased by adequate glycemic control. 9 In patients with Type 2 diabetes, magnesium deficiency seems to have a detrimental effect on insulin sensitivity and glucose homeostasis. It has been discovered that diabetes-related microvascular damage is linked to magnesium deficiency.…”

Section: Original Article Original Article Original Article Original ...mentioning

confidence: 99%

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Study of Serum Magnesium Level in Type 2 Diabetes Mellitus

Chowdhury MR,

Begum RA,

Khatun S

et al. 2024

JSWMC

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Background: Type 2 Diabetes Mellitus (DM) is the most prevalent metabolic disease associated with magnesium deficiency. Renal magnesium wasting can be made worse by insulin resistance and hyperglycemia increases the osmotic urinary excretion of magnesium. High incidence of hypomagnesaemia in Type 2 DM has been reported in different studies. Aims and Objectives: To assess status of serum magnesium level in patients with Type 2 diabetes mellitus. Materials and Methods: This cross-sectional analytical study was conducted in the Department of Biochemistry, Sylhet MAG Osmani Medical College, Sylhet between January 2021 and December 2021. Fifty-five type-2 diabetics and age and sex matched 55 healthy volunteers were included by applying non probability convenient sampling technique. Diabetics with acute complications, diarrhoea or other malabsorptive states, those taking alcohol or drugs such as amino glycosides, thiazide diuretics and pregnant women were excluded. All underwent fasting plasma glucose, serum magnesium and HbA1c levels. Results: The mean serum magnesium level was 1.67 ± 0.41 mg/dl and 2.02 ± 0.40 mg/dl in diabetics and non-diabetics respectively; difference was statistically significant (p=0.001). Hypomagnesaemia was more frequent in diabetic group [22 (40.0%) versus 2 (3.6%), p<0.001] compared to non-diabetics. Conclusion: Serum magnesium level is lower and hypomagnesaemia is more frequent in diabetics compared to the healthy subjects.

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Section: Discussionsupporting

confidence: 88%

Section: Discussionmentioning

confidence: 96%