Prevalence of Human Cytomegalovirus Infection among Human Immunodeficiency Virus Positive Women Receiving Antiretroviral Treatment at Federal Teaching Hospital Abakaliki, Ebonyi State, Nigeria

E, Nwafor Ifeanyi; Ogbu, Ogbonnaya

doi:10.4172/2254-609x.100073

Cited by 1 publication

(2 citation statements)

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“…It is, therefore, necessary to prevent the disease rather than treat it. We can do prevention by screening blood to avoid CMV transmission ( Emmanuel and Ogbu 2017 ). In addition, there is an urgent need for increasing awareness in society that infectious body fluids such as saliva and urine of infected children are an essential source of HCMV infection during pregnancy.…”

Section: Discussionmentioning

confidence: 99%

“…HCMV viral transmissions occur among all age groups, races, and socioeconomic classes throughout the modernised and developing parts of the world ( Emmanuel and Ogbu 2017 ). HCMV seroprevalence ranges from 40 % and may reach up to 100%, especially in high-risk populations like HIV-infected patients and those on immunosuppressive treatment ( Delvincourt et al 2014 ).…”

Section: Introductionmentioning

confidence: 99%

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Seroepidemiological Survey of Cytomegalovirus Infection among Pregnant Women in Sudan

Moglad,

Hassan,

Atta Elmanan

et al. 2023

Polish Journal of Microbiology

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Human Cytomegalovirus (HCMV) is a leading healthcare problem associated with stillbirth and congenital abnormalities. Determining the seroprevalence and the possible risk factors related to HCMV infections may be a cornerstone in preventing its complications. This cross-sectional study was conducted in Kassala and River Nile States to determine the seroprevalence and risk factors associated with HCMV infection in pregnant women. One hundred eighty-four (n = 184) blood specimens were collected from pregnant women from February 2018 to January 2020. Enzyme-linked immunosorbent assay (ELISA) was used to detect HCMV-specific IgG and IgM antibodies. Socio-demographical characteristics of the women were collected using structured questionnaires. The results showed that HCMV IgG was detected in 170 (92.4%) of the blood specimens, and IgM was detected in 29/93 (31.2%). There was a significant relationship between the history of miscarriage and the presence of IgG and IgM with a p-value = 0.001 and between HCMV IgM and gestational stage (p-value = 0.028). The study found a strikingly high seroprevalence of HCMV infections among pregnant women in the investigated States. This high percentage of illiterate housewives living in rural areas makes it possible to reduce the incidence of HCMV infection in pregnant women by improving their knowledge, attitude, and practice regarding the route of viral transmission, which may reflect in lowering the rate of congenital diseases in their infants.

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Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Seroepidemiological Survey of Cytomegalovirus Infection among Pregnant Women in Sudan

Moglad,

Hassan,

Atta Elmanan

et al. 2023

Polish Journal of Microbiology

View full text Add to dashboard Cite

show abstract

Prevalence of Human Cytomegalovirus Infection among Human Immunodeficiency Virus Positive Women Receiving Antiretroviral Treatment at Federal Teaching Hospital Abakaliki, Ebonyi State, Nigeria

Abstract: Background: Cytomegalovirus has been identified as the major cause of morbidity and mortality among neonates. It commonly occurs in immunocompromised and immunodepressed individuals.

Cited by 1 publication

References 32 publications

Seroepidemiological Survey of Cytomegalovirus Infection among Pregnant Women in Sudan

Seroepidemiological Survey of Cytomegalovirus Infection among Pregnant Women in Sudan

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