Prevalence of Hospital-Associated Disability in Older Adults: A Meta-analysis

Loyd, Christine; Markland, Alayne D.; Yue, Zhang; Fowler, Mackenzie E.; Harper, Sara A.; Wright, Nicole C.; Carter, Christy S.; Buford, Thomas W.; Smith, Kay Hogan; Kennedy, Richard E.; Brown, Cynthia J.

doi:10.1016/j.jamda.2019.09.015

Cited by 182 publications

(172 citation statements)

References 34 publications

Supporting

Mentioning

136

Contrasting

Unclassified

Order By: Relevance

“…Coronavirus disease 2019 (COVID- 19) has been reported in the Wuhan area of China's Hubei Province since the end of December 2019. Huanggang was the second city in China to be locked down only next to Wuhan.…”

Section: Introductionmentioning

confidence: 99%

Risk Factors for Mortality in Critically Ill Patients with COVID-19 in Huanggang, China: A Single-Centre Multivariate Pattern Analysis

Chen

Linli

Lei

et al. 2020

Preprint

View full text Add to dashboard Cite

To date, the coronavirus disease 2019 (COVID-19) has a worldwide distribution. Risk factors for mortality in critically ill patients, especially detailed self-evaluation indicators and laboratory-examination indicators, have not been well described. In this paper, a total of 192 critically ill patients (142 were discharged and 50 died in the hospital) with COVID-19 were included. Self-evaluation indicators including demographics, baseline characteristics and symptoms and detailed lab-examination indicators were extracted. Data were first compared between survivors and non-survivors. Multivariate pattern analysis (MVPA) was performed to identify possible risk factors for mortality of COVID-19 patients. MVPA achieved a relatively high classification accuracy of 93% when using both self-evaluation indicators and laboratory-examination indicators. Several self-evaluation factors related to COVID-19 were highly associated with mortality, including age, duration (time from illness onset to admission), and the Barthel index score. When the duration, age and Barthel index increased by one day, one year and one point, the mortality increased by 3.6%, 2.4% and 0.9% respectively. Laboratory-examination indicators including C-reactive protein (CRP), white blood cell (WBC) count, platelet count, fibrin degradation products (FDP), oxygenation index (OI), lymphocyte count and D-dimer were also risk factors. Among them, duration was the strongest predictor of all-cause mortality. Several self-evaluation indicators that can simply be obtained by questionnaires and without clinical examination were the risk factors of all-cause mortality in critically ill COVID-19 patients. The prediction model can be used by individuals to improve health awareness, and by clinicians to identify high-risk individuals.

show abstract

Section: Introductionmentioning

confidence: 99%

Risk Factors for Mortality in Critically Ill Patients with COVID-19 in Huanggang, China: A Single-Centre Multivariate Pattern Analysis

Chen

Linli

Lei

et al. 2020

Preprint

View full text Add to dashboard Cite

show abstract

“…A recently published meta-analysis showed that the random effects meta-analysis across the 16 included studies identified a combined prevalence of HAD as 31% (95% confidence interval [CI] = 25%-37%; P < .001), and the effect of year of study initiation on this finding was minimal. 2 Thus, despite significant changes in the healthcare system over time, including shortened lengths of stay and improved focus on quality, rates of HAD remain largely unchanged over the three decades it has been studied. This disability can result in the need for additional help in the home or even admission to a skilled nursing facility.…”

mentioning

confidence: 99%

After Three Decades of Study, Hospital‐Associated Disability Remains a Common Problem

Brown

2020

J American Geriatrics Society

Self Cite

View full text Add to dashboard Cite

show abstract

“…‐ Bedrest is toxic . Get rid of restraints themselves or their analogs: telemetry, continuous pulse oximeter, the Foley, the SCDs that do not do anything, etc.…”

Section: Questions To Ask Yourself As You Care For Your Older Patientsmentioning

confidence: 99%

To All Doctors: What You Can Do to Help as a Bunch of Older People Are About to Get Sick and Die

Perry

2020

J American Geriatrics Society

View full text Add to dashboard Cite

Prevalence of Hospital-Associated Disability in Older Adults: A Meta-analysis

Cited by 182 publications

References 34 publications

Risk Factors for Mortality in Critically Ill Patients with COVID-19 in Huanggang, China: A Single-Centre Multivariate Pattern Analysis

Risk Factors for Mortality in Critically Ill Patients with COVID-19 in Huanggang, China: A Single-Centre Multivariate Pattern Analysis

After Three Decades of Study, Hospital‐Associated Disability Remains a Common Problem

To All Doctors: What You Can Do to Help as a Bunch of Older People Are About to Get Sick and Die

Contact Info

Product

Resources

About