Prevalence of hip osteoarthritis and acetabular dysplasia in French and Japanese adults

Inoue, Koji; Wicart, P.; Kawasaki, Taku; Huang, Jian; Ushiyama, Toshio; Hukuda, Sinsuke; Courpied, Jean-Pierre

doi:10.1093/rheumatology/39.7.745

Cited by 118 publications

(97 citation statements)

References 6 publications

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“…Colon Study also reported in 26 [29] Cross-sectional (1) Patients aged 20-79 years at one hospital in France; (2) similar study was also conducted at a hospital in Japan France: n = 401; Japan: n = 782; Total: n = 1183…”

Section: Discussionmentioning

confidence: 76%

“…This included 20 recent estimates from 17 primary studies [1, 3, 5, 7, 9, 19, 22, 23, 27-30, 43, 44, 47, 54, 55] uncovered in the literature search, three [29,43,55] of which reported two estimates each, and 19 older estimates summarized in three previous review articles [26,36,38] on this topic. These 39 estimates ranged from 0.9% to 27.0% with a mean of 8.0%, a standard deviation of 7.0%, and a median of 5.3%.…”

Section: Resultsmentioning

confidence: 99%

“…The most common method used to diagnose overall prevalence of radiographic primary hip OA was that of Kellgren and Lawrence (K&L) (n = 23) [5,19,23,26,27,29,33,37,38,43,44,[47][48][49]54] followed by minimum joint space width (JSW) (n = 10) [3,9,26,28,30,43,49] and other classification schemes such as the Croft index (n = 2) [55], the American College of Rheumatology criteria (n = 1) [1], the Atlas of Osteoarthritis criteria (n = 1) [38], and unspecified methods (n = 2) [26]. The CV for the K&L method of diagnosis was 97.4% for K&L Grade C 2 and 73.1% for K&L C 3; the Croft C 3 method of diagnosis had a CV of 113.6%.…”

Section: Prevalence By Methods Of Diagnosismentioning

confidence: 99%

“…The methodological quality score for the 19 estimates of the prevalence of radiographic hip OA reported in the 16 primary studies [1, 3, 5, 7, 9, 19, 23, 27-30, 43, 44, 47, 54, 55] (three of which [29,43,55] reported on two separate cohorts each) uncovered in this review had a mean of 4.9 with a standard deviation of 0.9, a median of 5.0, and a range from 3.0 to 7.0 (Table 9). Only five of these estimates from four studies [9,[27][28][29] were considered of lower methodological quality (ie, score of 4 or lower), whereas 14 estimates from 12 studies [1,3,5,7,19,23,30,43,44,47,54,55] were considered of higher methodological quality (ie, score of 5 or higher). The mean prevalence reported in studies of lower methodological quality was 5.9% with a standard deviation of 4.0% and a median of 5.3% compared with a mean of 7.4%, a standard deviation of 6.4%, and a median of 6.7% for studies of higher methodological quality.…”

Section: Prevalence By Study Methodological Qualitymentioning

confidence: 99%

“…The majority of study populations were from Europe (n = 25) [1, 3, 5, 7, 9, 26-30, 44, 47-49, 54, 55] with a much small number of studies from North America (n = 6) [19,23,26,37,38,43] or Asia (n = 4) [26,29,43,55] and little representation from other geographic regions, including Africa (n = 2) [26], the Caribbean (n = 1) [26], and the Middle East (n = 1) [26]; there were no studies uncovered from South America or India. The mean prevalence in studies from Asia (1.4%) and Africa (2.8%) was much lower than that in North America (7.2%) or Europe (10.1%).…”

Section: Prevalence By Study Locationmentioning

confidence: 99%

See 4 more Smart Citations

Systematic Review of the Prevalence of Radiographic Primary Hip Osteoarthritis

Dagenais

Garbedian

Wai

2009

Clinical Orthopaedics &Amp; Related Research

173

121

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Hip osteoarthritis is a common cause of musculoskeletal pain in older adults and may result in decreased mobility and quality of life. Although the presentation of hip osteoarthritis varies, surgical management is required when the disease is severe, longstanding, and unresponsive to nonoperative treatments. For stakeholders to plan for the expected increased demand for surgical procedures related to hip osteoarthritis, including arthroplasty, it is important to first understand its prevalence. We conducted a systematic review by searching MEDLINE1 and EMBASE to identify recent English language articles reporting on the prevalence of radiographic primary hip osteoarthritis in the general adult population; references including studies and primary studies from previous systematic reviews were also searched. This strategy yielded 23 studies reporting 39 estimates of overall prevalence ranging from 0.9% to 27% with a mean of 8.0% and a standard deviation of 7.0%. Heterogeneity was noted in study populations, eligibility criteria, age and gender distribution, type of radiographs, and method of diagnosis. Although the association between radiographic hip osteoarthritis and the need for eventual surgical management is still unclear, this study supports assertions that hip osteoarthritis is a prevalent condition whose treatment will continue to place important demands on health services.

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Section: Discussionmentioning

confidence: 76%

Section: Resultsmentioning

confidence: 99%

Section: Prevalence By Methods Of Diagnosismentioning

confidence: 99%

Section: Prevalence By Study Methodological Qualitymentioning

confidence: 99%

Section: Prevalence By Study Locationmentioning

confidence: 99%

See 3 more Smart Citations

Systematic Review of the Prevalence of Radiographic Primary Hip Osteoarthritis

Dagenais

Garbedian

Wai

2009

Clinical Orthopaedics &Amp; Related Research

173

121

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Prevalence of falls and the association with knee osteoarthritis and lumbar spondylosis as well as knee and lower back pain in Japanese men and women

Muraki¹,

Akune²,

Oka³

et al. 2011

Arthritis Care & Research

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Objective. There is little information on falls by sex and age strata in Japan, and few factors associated with falls have been established. However, the association between bone and joint diseases and falls remains unclear. We examined prevalence of falls by sex and age strata, determined its association with radiographic osteoarthritis (OA) of the knee and lumbar spine, and determined knee and lower back pain after single and multiple falls. Methods. A questionnaire assessed the number of falls during 12 months preceding baseline. Knee and lumbar spine radiographs were read by Kellgren/Lawrence (K/L) grade; radiographic knee OA and lumbar spondylosis were defined as a K/L grade of 3 or 4. Knee and lower back pain were estimated by an interview. Results. A total of 587 men and 1,088 women (mean ؎ SD age 65.3 ؎ 12.0 years) were analyzed. During 1 year, 79 (13.5%) men and 207 (19.0%) women reported at least 1 fall. With increasing age, the prevalence of multiple falls was higher in women, but lower in elderly men age >60 years. In men, few factors were significantly associated with falls. In women, radiographic knee OA and lumbar spondylosis, as well as knee and lower back pain, were significantly associated with multiple falls without adjustment. Lower back pain and knee pain were independently associated with multiple falls in women after adjustment. Conclusion. Lower back pain and knee pain were significantly associated with multiple falls in women.

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Investigating the aspartic acid (D) repeat of asporin as a risk factor for osteoarthritis in a UK Caucasian population

Mustafa

Dowling

Chapman

et al. 2005

Arthritis & Rheumatism

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Objective. A compelling genetic association with osteoarthritis (OA) of 2 functional alleles in the aspartic acid (D) repeat of the asporin gene was recently reported in a Japanese population. Allele D13 of the repeat encoded OA protection, whereas allele D14 encoded OA susceptibility. The 2 alleles mediate differences in the capacity of asporin to inhibit the cartilage growth factor transforming growth factor ␤, with the D14 allele being a particularly potent inhibitor. Our objective was to assess whether the D repeat is associated with OA in UK Caucasians.Methods. The repeat was genotyped in 1,247 patients who had undergone elective joint replacement of the hip or the knee due to end-stage primary OA and in 748 age-matched controls.Results. The D13 allele was more common in controls, and the D14 allele was more common in patients. However, this trend was significant only for men who had undergone hip replacement (P ‫؍‬ 0.016, odds ratio 1.48, 95% confidence interval 1.09-2.01).Conclusion. Our data suggest that the asporin polymorphism is not a major influence on OA etiology in Caucasians. The results of our study do not question the veracity of the Japanese report. Instead, our study highlights the complex, heterogeneous nature of OA genetic susceptibility.A genetic association of 2 alleles of a functional polymorphism in the aspartic acid (D) repeat of the gene encoding asporin (ASPN) with primary osteoarthritis (OA) was recently reported in a Japanese population (1). Asporin is an extracellular protein belonging to the small leucine-rich proteoglycan family (2,3). These proteins can bind to and regulate the activity of the cartilage growth factor transforming growth factor ␤ (TGF␤). In the Japanese study, 10 alleles of the ASPN D repeat, containing 10-19 D residues, were detected. Allele D14 was significantly more common in 530 patients with knee OA than in 608 controls, with frequencies of 8.6% and 4.8%, respectively (P ϭ 0.00024, odds ratio [OR] 1.87, 95% confidence interval [95% CI] 1.3-2.6). This allele was also significantly more common in 593 patients with hip OA, with a frequency of 7.9% (P ϭ 0.0078, OR 1.70, 95% CI 1.1-2.5). The D13 allele was significantly less common in patients compared with controls. The associations were consistent in both men and women. No other alleles showed significant frequency differences. Subsequent function studies demonstrated that the D14 allele was particularly potent at inhibiting the TGF␤-mediated expression of the genes encoding the cartilage structural proteins aggrecan and type II collagen. The investigators had therefore identified OA-protective (D13) and OA-susceptible (D14) forms of asporin in the Japanese population. Our objective was to assess the role of this repeat polymorphism in OA development in a Caucasian population. PATIENTS AND METHODSCase-control cohort. The patients (n ϭ 1,247; 737 women and 510 men) were ascertained through the Nuffield Orthopaedic Centre in Oxford. Patients had primary OA and had undergone total joint replacement of a hip (n ϭ 9...

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Prevalence of hip osteoarthritis and acetabular dysplasia in French and Japanese adults

Abstract: : In a large number of subjects assessed by a single observer, this study confirms other previous reports that the relationship between acetabular dysplasia and risk of hip OA is negative.

Cited by 118 publications

References 6 publications

Systematic Review of the Prevalence of Radiographic Primary Hip Osteoarthritis

Systematic Review of the Prevalence of Radiographic Primary Hip Osteoarthritis

Prevalence of falls and the association with knee osteoarthritis and lumbar spondylosis as well as knee and lower back pain in Japanese men and women

Investigating the aspartic acid (D) repeat of asporin as a risk factor for osteoarthritis in a UK Caucasian population

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