Prevalence of herbal medicine use among patients with kidney disease: A cross-sectional study from Morocco

Touiti, Noufissa; Houssaïni, Tarik Sqalli; Iken, Imane; Benslimane, Abdelilah; Achour, Sanae

doi:10.1016/j.nephro.2019.01.007

Cited by 16 publications

(12 citation statements)

References 33 publications

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“…These results were in accordance with that of Zeggwagh et al (2008) who found that Artemisia herba-alba intake induced a pronounced jump in urinary output and glomerular filtration rate after Artemisia herba-alba treatment where the oral intake with Artemisia herba-alba caused a jump in urinary sodium and potassium excretion. Moreover, Touiti et al (2020) used Artemisia herba-alba to treat patients with kidney disease in nephrology department of University Hospital center Hassan II, Morocco.…”

Section: Discussionmentioning

confidence: 99%

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Artemisia restores systolic blood pressure, attenuates serum sodium/potassium levels and prevents cardiac oxidative stress in hypertension

Koriem

Saleh

El-Attar

2020

NFS

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Purpose This paper aims to evaluate systolic blood pressure (SBP), serum sodium/potassium levels and cardiac antioxidants after Artemisia herba-alba oral administration in spontaneous hypertensive rats (SHR). Design/methodology/approach Hypertension is a silent killer disease. The SHR model was used in this study due to the similarity of high blood pressure in human and rat. The SBP, serum sodium and potassium, urinary sodium and potassium, cardiac antioxidants and heart histology were examined in SHR after oral administration with 10 and 20% of the LD50 of Artemisia herba-alba during four weeks. Findings The LD50 of Artemisia herba-alba was found to be 1000 mg/kg. Doses of 100 mg/kg (10% LD50) and 200 mg/kg (20% LD50) were considered in the present study. The oral administration of SHR rats with Artemisia extract at 100 and 200 mg/kg decreased (p < 0.01) the body weights, SBP and serum sodium and potassium. Meanwhile, cardiac superoxide dismutase and gluthatione peroxidase were increased in SHR-treated rats. Histology of SHR cardiac tissues showed tissue degenerative but oral intake of 100 and 200 mg/kg artemisia exhibited normal muscle fibers, acidophilic cytoplasm and central nuclei. Originality/value The cardiovascular diseases are the first reason for high death rate in Western countries and collapsing economies due to hypertensive patients suffering high health-care costs. The advantage of hypertension Herba l treatment occurred due to its cheap and available source. Artemisia herba-alba leaves restored SBP, attenuated serum sodium/potassium levels and prevented cardiac oxidative stress in SHR.

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Section: Discussionmentioning

confidence: 99%

“…Many researchers have reported the potential of Artemisia herba-alba to cure diabetes mellitus (Al-Waili, 1986; Al-Shamaony et al , 1994; Marrifa et al , 1995). Artemisia herba-alba is used to treat kidney diseases (Touiti et al , 2019), diabetes and cancer (Hamza et al , 2019; Shawky, 2019).…”

Section: Introductionmentioning

confidence: 99%

Artemisia restores systolic blood pressure, attenuates serum sodium/potassium levels and prevents cardiac oxidative stress in hypertension

Koriem

Saleh

El-Attar

2020

NFS

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“…[5] Despite the variety of medicinal plants for treating kidney disorders, their use must be rational to avoid toxicity due to misuse. According to Touiti et al [6] about 50 % of hospitalized patients with kidney disease used medicinal plants. Among the main reasons for their use are belief, easy access, and lower cost.…”

Section: Introductionmentioning

confidence: 99%

“…Among the main reasons for their use are belief, easy access, and lower cost. [6] doi.org/10.1002/cbdv.202200022…”

Section: Introductionmentioning

confidence: 99%

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Diuretic and Antiurolithic Effect of Garcinia humilis (Vahl) C.D. Adams Leaves, a Medicinal Plant Native to South American Countries

Mariano

Pontioli

Silva

et al. 2022

Chemistry & Biodiversity

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This study evaluated the diuretic and antiurolithic effect of methanolic extract (MEGHL), dichloromethane (DCM), and ethyl acetate (EtA) fractions obtained from the leaves of Garcinia humilis, a medicinal plant known as achachairu and native to South American countries such as Bolivia, Peru, and Brazil. For the analysis of diuretic effect, the female rats received the treatment with MEGHL (3, 10, and 30 mg/kg), DCM (1, 3 and 10 mg/kg), EtA (1, 3, and 10 mg/kg), hydrochlorothiazide (HCTZ; 10 mg/kg), or vehicle (VEH) after an overload of saline solution. At the end 8 h of the experiment, the urinary parameters were measured. Additionally, the antiurolithic effect was analyzed, in which sodium oxalate was added in synthetic urine in the presence or absence of MEGHL, DCM, and EtA in different concentrations (0.1, 0.3, and 1 mg/mL). MEGHL, DCM, and EtA were able to promote 8-h diuresis in rats. MEGHL treatment at dose 30 mg/kg was accompanied by increased urinary Na + , K + and Cl À excretion. Moreover, the DCM and EtA fractions treatment increased K + and Cl À excretion in the urine, although it does not cause any change in Na + elimination. All the preparations were able to exert an antiurolithic effect in vitro, decreasing the number of calcium oxalate crystals of the monohydrate and dihydrate types. Taking together, the results presented herein showed that the preparations of G. humilis leaves are promising strategies to induce diuresis and antiurolithic effects.

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Challenges in the Storage of Herbal Medicine Products and Strategies for Sustainable Management

Devi,

Kumar

2023

Reference Series in Phytochemistry

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Prevalence of herbal medicine use among patients with kidney disease: A cross-sectional study from Morocco

Cited by 16 publications

References 33 publications

Artemisia restores systolic blood pressure, attenuates serum sodium/potassium levels and prevents cardiac oxidative stress in hypertension

Artemisia restores systolic blood pressure, attenuates serum sodium/potassium levels and prevents cardiac oxidative stress in hypertension

Diuretic and Antiurolithic Effect of Garcinia humilis (Vahl) C.D. Adams Leaves, a Medicinal Plant Native to South American Countries

Challenges in the Storage of Herbal Medicine Products and Strategies for Sustainable Management

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