Prevalence of Hepatitis C Virus Infection in US States and the District of Columbia, 2013 to 2016

Abstract

Key Points Question During 2013 to 2016, what proportion of adults were living with hepatitis C virus (HCV) infection in each US state? Findings In this survey study, US national HCV prevalence during 2013 to 2016 was 0.93% and varied by jurisdiction between 0.45% and 2.34%. Three of the 10 states with the highest prevalence and 5 of the 9 states with the highest number of HCV infections were in the Appalachian region. Meaning Regions with long-standing HCV epidemics, and those with newly emergent ones partly driven by the opioid crisis, face substantial HCV prevalence.

Hepatitis C Guidance 2019 Update: American Association for the Study of Liver Diseases–Infectious Diseases Society of America Recommendations for Testing, Managing, and Treating Hepatitis C Virus Infection

“…Since these recommendations were established in 2012, HCV epidemiology in the United States has changed. Hepatitis C infection incidence nearly quadrupled from 2010 to 2017, primarily driven by increased injection drug use related to the opioid epidemic . CDC viral hepatitis surveillance data indicate progressively increasing acute HCV infection incidence each year from 2009 through 2017.…”

“…Hepatitis C infection incidence nearly quadrupled from 2010 to 2017, primarily driven by increased injection drug use related to the opioid epidemic. (16)(17)(18)(19) CDC viral hepatitis surveillance data indicate progressively increasing acute HCV infection incidence each year from 2009 through 2017. Most of these new HCV infections occurred in persons born after 1965, with those aged 20-39 years accounting for the majority of cases.…”

Inflammatory and cardiovascular diseases biomarkers in chronic hepatitis C virus infection: A review

“…HCV has a global prevalence of 2.5% and infects 180 million people worldwide . In the United States, it is the most common blood borne infection affecting 0.8 persons in every 100 000 and causing significant morbidity and mortality . In 2016, over 2 million Americans had an opioid use disorder with 10% to 20% of those escalating to injection drug use .…”

“…1 In the United States, it is the most common blood borne infection affecting 0.8 persons in every 100 000 and causing significant morbidity and mortality. 2 In 2016, over 2 million Americans had an opioid use disorder with 10% to 20% of those escalating to injection drug use. 3 In this setting the prevalence of HCV has dramatically increased, especially in younger patients, with injection drug use (IDU) now being the primary mode of transmission in the US and a 2-fold increase in the incidence rate of acute HCV infection.…”

Liver Health Literacy and Health Status Among Adults With Hepatitis C: Implications for the Nursing Profession as Part of the 2030 Global Elimination Goal

“…Hepatitis C virus (HCV) is a blood‐borne virus, and its infection has emerged as a global health concern, with an estimated prevalence of 3% (2.3–3.5 million people) in the United States and 71 million people worldwide (Rosenberg et al, ; World Health Organization [WHO], ). While for some people hepatitis C is a short‐term illness, for 70% to 85% of those with HCV infection, the condition is long‐term and chronic.…”