Prevalence of hepatitis B virus and associated risk factors among adults patients at Dessie referral and Kemise general hospitals in northeastern Ethiopia

Abstract

Background and Aims: Hepatitis is an inflammation of the liver that can reason a variety of health problems and can be fatal. According to the most recent estimates of the Global Burden of Disease study and WHO, viral hepatitis is accountable for around 1.34 million deaths yearly, which is comparable to the yearly number of deaths from HIV/AIDS (1.3 million), malaria (0.9 million), and tuberculosis (1.3 million). This study aimed to assess the prevalence of the Hepatitis B virus and associated risk factors among adults patients at Dessie Referral and Kemise General Hospitals. Methods:The source for the data on Hepatitis B virus (HBV) was all adults aged≥18 years that were admitted and tested for HBV from September 2020 to February 2021 were included in the study. A total of 1283 adults were admitted out of which, 1080 adults have completed measurements and had been taken into consideration for this examination, and others had been excluded from the examination because of exclusion criteria. To meet our objective descriptive statistics, the χ 2 test and multiple logistic regression statistical models were used for data analysis.Results: In this study, a total of 1080 adults were included out of which 631 (58.4%) female and 449 (41.6%) were male with a mean age of 34(SD ±± 12.56) years. The overall prevalence of HBV among adults was 27.4% (95% confidence interval [CI];24.8-30.2). The results of this study showed that age 25-34(odds ratio[OR] = 3.6, p-value = 0.005), 35-44 (OR = 6.67, p-value <0.001), ≥45 (OR = 3.85, p-value = 0.005), male (OR = 4.36, p-value < 0.001), history of hospitalization (OR = 0.644, p-value = 0.04), family history of HBV (OR = 1.96, p-value = 0.005), and jaundice (OR = 2.50, p-value = 0.005) were significant risk factors of HBV. Conclusion:The prevalence of HBV in this study is 27.4%. The results of this study showed that age, male, history of hospitalization, family history of HBV, and jaundice were significant risk factors for Hepatitis B virus.

Risk factors associated with Hepatitis B virus infection among pregnant women attending public hospitals in Addis Ababa, Ethiopia

“…The family history of HBV was also significantly associated with HBV infection. This is in line with similar studies reported from Ethiopia [ 5 , 35 , 41 , 42 ], Egypt [ 6 ], Rwanda [ 46 ], and South Brazil [ 44 ]. This might be due to a lack of understuding about HBVtransmission methods and, the sharing of different personal and household items within the family, vertical transmission, and unsafe sexual practices.…”

“…This is similar to studies in Ethiopia [ 22 , 33 ] and Nigeria [ 34 ], indicating that socio-demographic characteristics were not risk factors for HBsAg positivity. On the contrary, other studies in Ethiopia [ 26 , 35 ], Eritrea [ 19 ], Sudan [ 36 ], Cameroon [ 37 ], and Thailand [ 38 ] found a significant association between socio-demographic factors, such as marital status, age, occupation, religion, and HBV infection.…”

Assessment of knowledge, Attitudes and Practices regarding Hepatitis B virus among Nurses in Bangladesh: a cross-sectional study

“…Religion and marital status were not significantly associated with attitude of HBV infection. A similar study was conducted to assess the Prevalence of HBV and associated risk factors among adult patients at Dessie referral and Kemise general hospitals in northeastern Ethiopia [49].…”

An agent-based model to simulate the transmission dynamics of bloodborne pathogens within hospitals

“…The initial prevalence . We retrieved age-based HBV seroprevalence from Mohammed et al (2022) (9), who explored HBV infections in two Ethiopian hospitals.…”