Prevalence of hepatitis B virus in the Kurram Agency, Pakistan: A 5-year observational study in a war-affected region

Hussain, Shahzad; Ali, Zameer

doi:10.1016/j.jcv.2016.06.009

Cited by 6 publications

(3 citation statements)

References 8 publications

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“…This is the first study in which efficacy of an awareness activity has been investigated as opposed to prior knowledge of the people or the general prevalence of disease [14, 15]. The ratio of males to females in the study is about 1:1 which is similar to distribution of participants in another study done in 2019 [16].…”

Section: Discussionsupporting

confidence: 53%

Hepatitis B and C in Pakistan: A community survey

Javed¹,

Nadeem²,

Ghazanfar³

2019

Cureus

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ObjectiveTo assess the efficacy of awareness campaign aimed at Hepatitis B and C in a rural community in Rawalpindi, Pakistan.MethodsThis is a cross-sectional study conducted on patients from a primary health care facility in Rawalpindi. The duration of the study was three months (April 2019 to June 2019). Patients who were registered at the facility were included after consent had been obtained. The data was collected through a self-constructed questionnaire. The data obtained was analyzed on IBM's statistical package for the social sciences (SPSS) version 21 (IBM, Armonk, NY).ResultsOut of 35 participants, 16 (46%) were males and 19 (54%) were females. The mean age of the participants was 43.82 ± 19.56 years. The mean number of people in the house was 7.54 ± 3.88. Twenty nine (84%) participants were married while six (16%) participants were not. A majority of the participants had good prior knowledge about Hepatitis B and C. However, a few confusions remained about the mode of transmission, the vector for transmission if any and vaccination protocols. The campaign proved to reinforce many concepts and clear potential confusions of the participants.ConclusionsThis attempt at improving awareness proved to be fruitful. There is a dire need to ensure that multiple activities are organized so that the burden of the disease may be reduced. There will be a strong network of communication for flow of information if the activities occur regularly and in a focused manner.

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Section: Discussionsupporting

confidence: 53%

Hepatitis B and C in Pakistan: A community survey

Javed¹,

Nadeem²,

Ghazanfar³

2019

Cureus

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“…Interior Sindh, Karachi, Southern Punjab, Kurrum agency, Northern Waziristan and some parts of Lahore are reported to have HBV prevalence of >5% [10,11,12,13,14,15]. In Pakistan, HBV reportedly shows 44.45% association with chronic liver diseases [16].…”

Section: Hbv Endemicity Is Intermediate In Pakistan With An Estimatedmentioning

confidence: 99%

Age-wise and Gender-wise Prevalence of Hepatitis B Virus (HBV) Infection in Lahore, Pakistan

Nazeer

Tipu

2019

BSR

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Background The prevalence of hepatitis B virus (HBV) in the Pakistani population has been reported previously, however, studies with a city-oriented approach and focus on age and gender distribution are very limited. Therefore, the current study was designed to unravel the age-wise and gender wise prevalence of HBV in Lahore, Pakistan. Methods A total of 350 blood samples of both male and female patients who visited National Genetic Laboratory, Lahore between February 2019 and July 2019 and who were suspected of HBV infection were screened. Sandwich based ELISA was used to detect rapid hepatitis B surface antigen (HbsAg) according to the manufacturer’s instruction. Real time PCR was used to detect HBV using HBV Rotor Gene PCR kit. Results Out of 350 blood samples screened for HBV infection (n= 350), 180 (51.43%) were of males and 170 (48.57%) were of females. Mean age (years) with SD (standard deviation) of the screened population was 37.22 ± 12.16 years. Overall, 224 samples (64%) were found to be positive for HBV infection. In our study, the number of females with this infection (52.24%) was slightly higher than males (47.76%). However, we observed no statistically significant difference (p = 0.225) between them. Conclusion Our study concludes that HBV is highly prevalent in Lahore, Pakistan. Females are slightly more susceptible to HBV infection as compared to males. This study also reports that HBV is more prevalent in the 20-40 age group.

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“…According to the 2018 Hepatitis B (HepB) guidelines set by American Association of the Study of Liver Disease (AASLD) all citizens born in a country with ≥ 2% prevalence of hepatitis B surface antigen (HBsAg) are at high risk of chronic hepatitis B (CHB) and need to be screened [1]. Several studies conducted in the past decade across various regions of Pakistan among various groups observed HBsAg seroprevalence of ≥ 3% [2][3][4][5][6]. Khyber Pukhtunkhwa (KP) province has a huge burden of hepatitis B with over 10 million chronic carriers [7].…”

Section: Introductionmentioning

confidence: 99%

Assess the knowledge of dentists regarding Hepatitis B serological profile: a cross-sectional study

Tariq

Tariq²,

Tareen

et al. 2020

J Infect Dev Ctries

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Introduction: The primary aim of the study was to determine the knowledge of dental practitioners regarding HBV serological markers. Second objective was to determine prevalence of occupational exposures to HBV amongst dentists. Methodology: A questionnaire was constructed pertaining to various aspects of HBV serology; validated by an expert panel; and piloted at 49 dentists. A Cronbach-alpha value of 0.7 was attained and thus extensive survey was conducted among dentists in routine practise treating hepatitis B patients at dental teaching hospitals in Peshawar, KP. The data was analysed using SPSS v.22. Results: A response rate of 58% (a total of 290 respondents) was attained. All respondents were vaccinated against HBV. Over 50% reported not to follow Standard precautions for every patient. Overall, 20.3% experienced HBV exposure, eight were administered PEP. Fifty-four percent of FYs; 74.5% PGTs and 71.6% of faculty dentists correctly answered: HBsAg to be the ‘serological hallmark of HBV infection’; this was the most correctly answered question. Sixty-four percent dentists failed to identify the infectious carrier phase. Over 50% of dentists in each category failed to correctly answer 5/8 of the HBV serology. Conclusions: Over 20% reported HBV occupational exposure but zero transmissions. Majority of dentists did not have correct information on HBV serological profile which may jeopardise cross-infection control. Further education on HBV serological markers and its clinical relevance to dentistry along with stringent adherence to Standard precautions is recommended.

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Prevalence of hepatitis B virus in the Kurram Agency, Pakistan: A 5-year observational study in a war-affected region

Cited by 6 publications

References 8 publications

Hepatitis B and C in Pakistan: A community survey

Hepatitis B and C in Pakistan: A community survey

Age-wise and Gender-wise Prevalence of Hepatitis B Virus (HBV) Infection in Lahore, Pakistan

Assess the knowledge of dentists regarding Hepatitis B serological profile: a cross-sectional study

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