Prevalence of hepatitis B surface antigen in persons with liver disorders in Jordan

Abstract

585ducing strain in Europe indicate the increasing spread of ROB-1 beta-lactamase producing strains among clinical isolates of Haemophilus hzfluenzae. We found that ROB-1 production in strain 86 242 is mediated by a plasmid, designated pCFF 242. Its molecular weight (4,4 Kb) is identical to that of R-ROB from original ROB-1 beta-lactamase producing Haemophilus influenzae. Moreover, digestion patterns with restriction endonucteases of plasmid DNA from strain 86 242 were identical to those of R-ROB. This finding is surprising in view of the geographical origin of the two strains. Medeiros et al. (1) nevertheless reported that plasmids encoding for ROB-t in humanHaernophilus influenzae strains isolated in the USA were strikingly similar, regardless of where they were isolated. However, the close relationship between the ROB-I encoding plasmids of the reference strain and the first strain isolated in Europe is a very interesting observation regarding of the epidemiology of ROB-I producing Haemophihts infIuenzae strains.