Prevalence of hepatitis B and C viral infection according to the data on fetal outcomes in Moscow in 2015-2017

Зайратьянц, О. В.; Yushchuk, N D; Хрипун, А И; Znoyko, O. O.; Gudkova, Svetlana B.; Orekhov, O O; Krasnenkova, Svetlana F.; Zhuravleva, A V

doi:10.17116/patol20198102129

“…В 2018 г. в Москве впервые по определенной методике было проведено ретроспективное исследование оценки смертности от ВГ с учетом всех причин летальных исходов больных, в сыворотке крови которых при жизни были выявлены маркеры ВГВ и ВГС [12,13]. В этом исследовании был выполнен раздельный статистический учет смертей, основанный как на одной причине, которая рассматривается как первоначальная в соответствии с правилами МКБ-10 (Underlying Cause Of Death, UCOD), так и на множестве причин смерти (Multiple Causes Of Death, MCOD).…”

unclassified

Estimation of mortality from viral hepatitis B and C in 2019 in four regions of the Russian Federation according to primary medical documentation

Znoyko¹,

Yushchuk²,

Зайратьянц³

et al. 2020

Infectious diseases: News, Opinions, Training

0

View full text Add to dashboard Cite

Финансирование. Настоящее исследование выполнено в рамках государственного задания № 056-00149-18-02 «Оценка нагрузки инфекции вируса гепатита С на популяцию и связанной с ней смертности в Российской Федерации с последующим прогностическим моделированием эпидемиологической ситуации в зависимости от охвата противовирусной терапией больных хроническим гепатитом С». Конфликт интересов. Авторы заявляют об отсутствии конфликта интересов. Вклад авторов. Все авторы внесли эквивалентный вклад в подготовку публикации.

show abstract

Etiological and Epidemiological Characteristics of Lethality from Acute Viral Hepatitis, Kyrgyzstan, 2009−2018

Ногойбаева

¹

,

Тобокалова

²

2020

Zhurnal Mikrobiologii Epidemiologii i Immunobiologii

View full text Add to dashboard Cite

Purpose. Study of the etiological structure of lethality from acute viral hepatitis and its comparison with morbidity and mortality for the period of 2009−2018.Materials and methods. State Reporting Forms No. 1 “Report on Infectious, Parasitic and Non-Infectious Diseases” for the period of 2009−2018 were studied. The data was processed by the Microsoft Office Excel statistical package.Results. In Kyrgyzstan, during the period of 2009−2018, 138,612 cases of acute viral hepatitis (AVH) were detected, of which 109 patients had fatal outcomes. In the general structure of the latter, the proportions of patients with acute hepatitis B (AHB 36.7%) and A (AHA, 35.7%) were approximately the same. In every fifth case, “unverified acute viral hepatitis (UAVH)” was diagnosed (22.9%). Acute hepatitis C (AHC) was the cause of death in 4 patients (3%), and hepatitis D virus (HDV) infection in 1 patient. Among the deceased, there were no cases of hepatitis E. Lethality from AHB was recorded in 5 children, and from hepatitis C in one child. At the same time, 9 out of 25 patients with “Unverified Acute Viral Hepatitis” were children. Over the period of 2009−2018, the incidence of AHB was 31.3 times lower than that of all AVH in general (240.9 and 7.7⁰/0000, AVH and AHB, respectively), the mortality rate was 2.7 times lower (0.19 and 0.07⁰/0000, AVH and AHB, respectively), and the lethality rate was 11.4 times higher (7.9 and 89.8⁰/0000, AVH and AHB, respectively). The average incidence of AHB in children was 6.4 times lower (7.7 and 1.2⁰/0000, total and children, respectively), the mortality rate was 2.3 times lower (0.07 and 0.03⁰/0000, total and children, respectively), and the lethality rate was 1.8 times higher (89.8 and 165.9⁰/0000, total and children, respectively).Conclusion. The existence of morbidity and lethality in adults and children from acute hepatitis indicates a high disease burden for the country. The high proportion of AHB and AHA in the structure of AVH mortality requires improving the quality of immunization of children and expanding the coverage of adults with vaccination against these viral hepatitis. The increase in lethality against the background of a tenfold decrease in the incidence of AVH points out that the number of patients who have died from this pathology does not decrease.

show abstract

Etiological and Epidemiological Characteristics of Lethality from Acute Viral Hepatitis, Kyrgyzstan, 2009−2018

Ногойбаева

¹

,

Тобокалова

²

2020

Journal of microbiology, epidemiology and immunobiology

1

0

View full text Add to dashboard Cite

Purpose. Study of the etiological structure of lethality from acute viral hepatitis and its comparison with morbidity and mortality for the period of 2009−2018.Materials and methods. State Reporting Forms No. 1 “Report on Infectious, Parasitic and Non-Infectious Diseases” for the period of 2009−2018 were studied. The data was processed by the Microsoft Office Excel statistical package.Results. In Kyrgyzstan, during the period of 2009−2018, 138,612 cases of acute viral hepatitis (AVH) were detected, of which 109 patients had fatal outcomes. In the general structure of the latter, the proportions of patients with acute hepatitis B (AHB 36.7%) and A (AHA, 35.7%) were approximately the same. In every fifth case, “unverified acute viral hepatitis (UAVH)” was diagnosed (22.9%). Acute hepatitis C (AHC) was the cause of death in 4 patients (3%), and hepatitis D virus (HDV) infection in 1 patient. Among the deceased, there were no cases of hepatitis E. Lethality from AHB was recorded in 5 children, and from hepatitis C in one child. At the same time, 9 out of 25 patients with “Unverified Acute Viral Hepatitis” were children. Over the period of 2009−2018, the incidence of AHB was 31.3 times lower than that of all AVH in general (240.9 and 7.7⁰/0000, AVH and AHB, respectively), the mortality rate was 2.7 times lower (0.19 and 0.07⁰/0000, AVH and AHB, respectively), and the lethality rate was 11.4 times higher (7.9 and 89.8⁰/0000, AVH and AHB, respectively). The average incidence of AHB in children was 6.4 times lower (7.7 and 1.2⁰/0000, total and children, respectively), the mortality rate was 2.3 times lower (0.07 and 0.03⁰/0000, total and children, respectively), and the lethality rate was 1.8 times higher (89.8 and 165.9⁰/0000, total and children, respectively).Conclusion. The existence of morbidity and lethality in adults and children from acute hepatitis indicates a high disease burden for the country. The high proportion of AHB and AHA in the structure of AVH mortality requires improving the quality of immunization of children and expanding the coverage of adults with vaccination against these viral hepatitis. The increase in lethality against the background of a tenfold decrease in the incidence of AVH points out that the number of patients who have died from this pathology does not decrease.

show abstract

Prevalence of hepatitis B and C viral infection according to the data on fetal outcomes in Moscow in 2015-2017

Cited by 3 publications

References 4 publications

Estimation of mortality from viral hepatitis B and C in 2019 in four regions of the Russian Federation according to primary medical documentation

Estimation of mortality from viral hepatitis B and C in 2019 in four regions of the Russian Federation according to primary medical documentation

Etiological and Epidemiological Characteristics of Lethality from Acute Viral Hepatitis, Kyrgyzstan, 2009−2018

Etiological and Epidemiological Characteristics of Lethality from Acute Viral Hepatitis, Kyrgyzstan, 2009−2018

Contact Info

Product

Resources

About