Prevalence of hepatitis A virus as cause of acute viral hepatitis in central Karnataka, India

Sarthi, Manjunatha; Kumar, Gunjan; Jayasimha, V. L.; Kumar, Chethan S; Patil, Satish S.; Taj, K.; Basavarajappa, K G

doi:10.18203/2349-3291.ijcp20163998

Cited by 4 publications

(4 citation statements)

References 7 publications

(9 reference statements)

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“…Routine serological testing for HEV is not popular. 11 Increase prevalence of HEV and HAV co-infections are seen in recent times. 12 This study was conducted to investigate the occurrence of Hepatitis E virus infection in patient screened for hepatitis A virus.…”

Section: Introductionmentioning

confidence: 99%

Occurrence of Hepatitis E virus infection in patients screened for Hepatitis A virus

Kannur¹,

Shetty²

2021

IJMR

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: Infectious hepatitis can be caused by Hepatitis A and Hepatitis E viruses. Hepatitis E infection is a water-borne disease transmitted by faeco-oral route. It is a cause of major health problems in developing countries. Outbreaks can happen due to improper hygiene and poor sanitation. Hepatitis E infection shows similar mode of transmission and clinical features of Hepatitis A infection. : This study was conducted to investigate the occurrence of Hepatitis E virus infection in patients screened for hepatitis A virus.: This prospective surveillance study was conducted between March 2020 to March 2021 on 57 serum samples which is came for the screening of anti-Hepatitis A virus IgM by enhanced Chemiluminescence method. These samples were collected and tested for anti- Hepatitis E virus IgM by Enzyme linked immunosorbent assay.: Among 57 samples, 11 samples (19.3%) were positive for Hepatitis A Virus IgM, 13 samples (22.8%) were positive for Hepatitis E virus IgM, and 7 samples (12.3%) were positive for both.: Hepatitis E virus infections were more than Hepatitis A virus. Hepatitis E and Hepatitis A virus co- infection was also observed. Screening of both viruses is suggested for infectious hepatitis.

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Section: Introductionmentioning

confidence: 99%

Occurrence of Hepatitis E virus infection in patients screened for Hepatitis A virus

Kannur¹,

Shetty²

2021

IJMR

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“…This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/) which permits copy and redistribute the material just in noncommercial usages, provided the original work is properly cited. both developing and developed countries (5)(6)(7)(8)(9)(10)(11)(12). Despite the availability of vaccines, prophylactic measures, and improved sanitation, it is affecting millions of children every year (8).…”

Section: Introductionmentioning

confidence: 99%

Prevalence of Sonographic Signs in Children with Acute Hepatitis in Zahedan City, Southeast of Iran

Sistani¹,

Nouri²,

Mashouri³

et al. 2020

Int J Infect

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Background: Acute viral hepatitis is a common infection in developing countries among children. Different diagnostic methods for acute hepatitis has been introduced. Objectives: In this study, we have determined the prevalence of sonographic signs in children with acute hepatitis. Methods: A total of 383 children with acute hepatitis were studied in Zahedan city, southeast of Iran. The sampling method was by the enumeration of the cases. Patients underwent ultrasonography in which their sonographic signs of acute hepatitis were investigated and analyzed. Results:The mean age of children was 6.1 ± 2.8 years, with 211 (55.1%) males and 172 (44.9%) females. The prevalence of gallbladder wall edema was 20.1% (77 children), periportal lymphadenopathy 15.1% (58 children), hepatomegaly 4.9% (19 children), increased liver echogenicity 53.0% (203 children), decreased liver echogenicity 15.4% (59 children), splenomegaly 1.8% (7 children), and periportal hyperechogenicity 32.4% (124 children). Conclusions:The results indicate that the most common sonographic signs of patients with acute hepatitis were increased liver echogenicity and periportal hyperechogenicity.

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“…Acute viral hepatitis is a major public health problem worldwide. [1][2][3][4][5][6] Hepatitis A, B, C and E are the four major hepatotropic viruses causing viral hepatitis. Hepatitis D virus or Hepatitis Delta virus is not included in this group as it can propagate only in the presence of Hepatitis B virus and is now considered to be a sub viral satellite.…”

Section: Introductionmentioning

confidence: 99%

Clinico-epidemiological profile of hepatitis A virus and hepatitis E virus co-infection in pediatric age group: a hospital based retrospective study

Handa

Wasim

Kalra

et al. 2019

Int J Contemp Pediatr

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Background: Hepatitis-A virus (HAV) and Hepatitis E virus (HEV) are two major hepatotropic viruses of great public health importance in the developing countries like India. Both HAV and HEV are enterically transmitted and there are speculations that their co-infection might be associated with a more severe clinical course and increased rate of mortality. The objective of this study is to determine the prevalence, clinical features and biochemical parameters of Hepatitis A and Hepatitis E co-infection in hospitalized patients at a tertiary care centre in Uttarakhand.Methods: It is a retrospective study, covering a period of 4years and conducted in Himalayan Institute of Medical Sciences, SRHU Jolly Grant, Dehradun. Records of the patients with Hepatitis A and Hepatitis E co-infection were retrieved and analyzed.Results: Out of total 125 patients of acute viral hepatitis, 13 patients had HAV and HEV co-infection. 100% of the patients with co-infection presented with complaints of fever and jaundice, followed by 76.92% with vomiting, 69.23% with pruritis, 61.53% with pain in abdomen and 23.07% with altered sensorium. Mean Bilirubin, ALT, AST were 8.69±7.27 mg/dl, 2030.69±1726.93IU/L and 1880.07±1881.11IU/L respectively. Average duration of stay was 8.2 days. Encephalopathy was seen in 2 patients. However, no mortality was reported.Conclusions: Co-infection of HAV and HEV is not rare in pediatric age group. Knowledge about this will be of immense help for planning of future vaccination strategies and for better sanitation program in developing countries like India.

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Prevalence of hepatitis A virus as cause of acute viral hepatitis in central Karnataka, India

Cited by 4 publications

References 7 publications

Occurrence of Hepatitis E virus infection in patients screened for Hepatitis A virus

Occurrence of Hepatitis E virus infection in patients screened for Hepatitis A virus

Prevalence of Sonographic Signs in Children with Acute Hepatitis in Zahedan City, Southeast of Iran

Clinico-epidemiological profile of hepatitis A virus and hepatitis E virus co-infection in pediatric age group: a hospital based retrospective study

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