Prevalence of hemoplasmas and &lt;i&gt;Bartonella&lt;/i&gt; species in client-owned cats in Beijing and Shanghai, China

Zhang, Yingxin; Zhang, Zhixuan; Lou, Yinying; Yu, Yonglan

doi:10.1292/jvms.20-0681

Cited by 12 publications

(16 citation statements)

References 28 publications

(34 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

“…In the current study, B. henselae-seropositive cats were significantly older than B. henselae-seronegative cats. This is consistent with previous studies suggesting that older cats are more commonly infected with B. henselae, possibly due to the fact that they have more time to be exposed to the microorganism [6,18].…”

Section: Discussionsupporting

confidence: 93%

“…In addition, younger cats, especially those under 2 years of age, are more likely to present with bacteraemia compared to older cats, while the latter appear to be more likely to become seropositive compared to the former [ 6 , 7 , 8 , 9 , 10 , 11 , 12 ]. Cats with outdoor access are more likely to become infected due to increased access to flea-infested environments [ 11 , 13 , 14 , 15 , 16 , 17 , 18 ]. Similarly, multi-cat households are a risk factor for Bartonella infection due to the increased number of potential hosts (other infected cats) and vectors [ 19 ].…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Prevalence and Risk Factors for Bartonella spp. and Haemoplasma Infections in Cats from Greece

Kokkinaki

Saridomichelakis

Skampardonis

et al. 2022

Veterinary Sciences

View full text Add to dashboard Cite

Bartonellosis and haemoplasmosis are vector-borne diseases with global impact on the health of domestic cats and of zoonotic importance. The aim of this study was to describe the epidemiological aspects of various populations of cats infected with Bartonella spp. or haemoplasma species. The populations evaluated included client-owned cats, stray cats and cats that live in breeding catteries in Greece. A total of 452 cats were prospectively enrolled into the study. A commercially available indirect immunofluorescence antibody testkit was used for the detection of Bartonella henselae IgG antibodies in serum. PCRs for the detection of Bartonella spp. and haemoplasma species DNA in the blood were also performed in a subgroup of 242 of the 452 cats. Risk factors for B. henselae seropositivity and infection with the haemoplasma species were determined using multivariable analysis. Overall, 160 (35.4%) of the 452 cats were seropositive for B. henselae. Seven (2.9%) and 46 (19%) of the 242 cats were PCR-positive for Bartonella spp. and haemoplasma species, respectively. The factors associated with B. henselae seropositivity, based on multivariate analysis, included older age, outdoor access, living region and flea infestation. Non-administration of ectoparasiticides was associated with haemoplasma species infection. This study shows a high prevalence of seropositivity for B. henselae and a relatively high prevalence of infection with haemoplasma species. Therefore, it is necessary to establish optimal strategies for the prevention of Bartonella spp. and haemoplasma species infections, considering the high-risk groups of cats identified in this study.

show abstract

Section: Discussionsupporting

confidence: 93%

Section: Introductionmentioning

confidence: 99%

Prevalence and Risk Factors for Bartonella spp. and Haemoplasma Infections in Cats from Greece

Kokkinaki

Saridomichelakis

Skampardonis

et al. 2022

Veterinary Sciences

View full text Add to dashboard Cite

show abstract

“…In the present study, 16.13% of the cats were positive for Mycoplasma spp. with CMhm (8.6%) more frequent than Mhf (6.45%), similar to previous studies conducted in Thailand (Do et al, 2020(Do et al, , 2021Kaewmongkol et al, 2020), South Korea (Hwang et al, 2016) and China (Kaewmongkol et al, 2017;Liu et al, 2016;Zhang et al, 2021). Moreover, CMhm was the only Mycoplasma species detected in fleas from cats (7.53%), in line with what was previously described in UK and Australia (Barrs et al, 2010).…”

Section: Discussionsupporting

confidence: 90%

Occurrence and bacterial loads of Bartonella and haemotropic Mycoplasma species in privately owned cats and dogs and their fleas from East and Southeast Asia

Zarea

Bezerra‐Santos

Nguyen

et al. 2022

Zoonoses and Public Health

View full text Add to dashboard Cite

Bartonella spp. and haemoplasmas are pathogens of veterinary and medical interest with ectoparasites mainly involved in their transmission. This study aimed at molecular detection of Bartonella spp. and haemoplasmas in cats (n = 93) and dogs (n = 96), and their related fleas (n = 189) from countries in East and Southeast Asia. Ctenocephalides felis was the dominant flea species infesting both cats (97.85%) and dogs (75%) followed by Ctenocephalides orientis in dogs (18.75%) and rarely in cats (5.2%). Bartonella spp. DNA was only detected in blood samples of flea‐infested cats (21.51%) (p < .0001, OR = 27.70) with Bartonella henselae more frequently detected than Bartonella clarridgeiae in cat hosts (15.05%, 6.45%) and their associated fleas (17.24%, 13.79%). Out of three Bartonella‐positive fleas from dogs, two Ct. orientis fleas carried Bartonella vinsonii subsp. berkhoffii and Bartonella clarridgeiae, while the 3rd flea (Ct. felis) carried Candidatus Bartonella merieuxii. Felines represented a risk factor for Bartonella spp. infections, where fleas collected from cats (32.25%) presented an increased likelihood for Bartonella spp. occurrence (p < .0001, OR = 14.76) than those from dogs (3.13%). Moreover, when analysing infectious status, higher Bartonella spp. DNA loads were detected in fleas from bacteraemic cats compared to those from non‐bacteraemic ones (p < .05). The haemoplasma occurrence was 16.13% (15/93) and 4.17% (4/96) in cat and dog blood samples from different countries (i.e. Indonesia, Malaysia, the Philippines, Taiwan and Thailand), with cats more at risk of infection (p < .01, OR = 5.96) than dogs. Unlike Bartonella spp., there was no evidence for flea involvement in the hemoplasmas' transmission cycle, thus supporting the hypothesis of non‐vectorial transmission for these pathogens. In conclusion, client‐owned cats and dogs living in East and Southeast Asia countries are exposed to vector‐borne pathogens with fleas from cats playing a key role in Bartonella spp. transmission, thus posing a high risk of infection for humans sharing the same environment.

show abstract

“…CMt infection was first reported in Switzerland in 2005 [ 19 ]. CMhm has the highest prevalence worldwide and the prevalence of Mhf and CMt is similar [ 1 – 3 , 5 , 6 ]; the prevalence of CMhm , Mhf , and CMt is 8.5–46.7%, 0.5–21.3%, and 1–10%, respectively [ 2 , 3 , 6 ]. Although CMhm is known to be more common than Mhf , no studies in Korea have compared the prevalence of these 3 species.…”

Section: Discussionmentioning

confidence: 99%

“…Feline hemotropic mycoplasmosis (hemoplasmosis) is primarily associated with 3 hemotropic Mycoplasma species that attach themselves to the surface of red blood cells (RBCs) in cats: Mycoplasma haemofelis ( Mhf ), Candidatus Mycoplasma haemominutum ( CMhm ), and Candidatus Mycoplasma turicensis ( CMt ) [ 1 – 6 ]. Molecular studies have demonstrated the existence of Mhf and CMhm species since 2007 and CMt species since 2017 in feral cats in Korea [ 7 – 9 ].…”

Section: Introductionmentioning

confidence: 99%

Two Clinical Cases of Feline Hemoplasmosis in Korea

et al. 2022

View full text Add to dashboard Cite

Feline hemotropic mycoplasmosis (hemoplasmosis) is an infection of the red blood cells caused by the Mycoplasma haemofelis (Mhf), Candidatus Mycoplasma haemominutum (CMhm), and Candidatus Mycoplasma turicensis (CMt). The existence of Mhf, CMhm, and CMt has been demonstrated in feral cats in Korea using molecular methods, but no clinical cases have yet been reported. This study reports 2 clinical cases of hemotropic mycoplasmosis caused by CMhm and CMt in 2 anemic cats. The first case was a client-owned intact female domestic shorthair cat that presented with fever, pale mucous membranes, and normocytic normochromic non-regenerative anemia. Prior to referral, an immunosuppressive prednisolone dose was administered at the local veterinary clinic for 1 month. The cat was diagnosed with high-grade alimentary lymphoma. Organisms were found on the surface of the red blood cells on blood smear examination. The second case was of a rescued cat that presented with dehydration and fever. The cat had normocytic normochromic non-regenerative anemia. Necropsy revealed concurrent feline infectious peritonitis. Polymerase chain reaction assay targeting 16S rRNA revealed CMhm infection in case 1 and dual infection of CMhm and CMt in case 2. Normocytic normochromic non-regenerative anemia was observed in both cats before and during the management of the systemic inflammation. This is the first clinical case report in Korea to demonstrate CMhm and CMt infections in symptomatic cats.

show abstract

Prevalence of hemoplasmas and <i>Bartonella</i> species in client-owned cats in Beijing and Shanghai, China

Cited by 12 publications

References 28 publications

Prevalence and Risk Factors for Bartonella spp. and Haemoplasma Infections in Cats from Greece

Prevalence and Risk Factors for Bartonella spp. and Haemoplasma Infections in Cats from Greece

Occurrence and bacterial loads of Bartonella and haemotropic Mycoplasma species in privately owned cats and dogs and their fleas from East and Southeast Asia

Two Clinical Cases of Feline Hemoplasmosis in Korea

Contact Info

Product

Resources

About