Prevalence of Helicobacter pylori infection in children from an urban community in north-east Brazil and risk factors for infection

Marzano‐Rodrigues, Maria Noel; Queiroz, Dulciene Maria Magalhães; Filho, José Gomes Bezerra; Pontes, Lígia K; Rodrigues, Rodrigo T; Braga, Lúcia Libanez Bessa Campelo

doi:10.1097/00042737-200402000-00013

Cited by 51 publications

(55 citation statements)

References 18 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…In agreement with previously published data on the prevalence of H. pylori infection in the Portuguese population in paediatric age, 39% of the patients were H. pylori positive [12]. The presence of the infection was associated with older patients and, in keeping with previous studies, gender did not constitute a risk factor for H. pylori infection [13].…”

Section: Discussionsupporting

confidence: 91%

Helicobacter pylori colonization of the adenotonsillar tissue: Fact or fiction?

Vilarinho

Guimarães

Ferreira

et al. 2010

International Journal of Pediatric Otorhinolaryngology

View full text Add to dashboard Cite

Section: Discussionsupporting

confidence: 91%

Helicobacter pylori colonization of the adenotonsillar tissue: Fact or fiction?

Vilarinho

Guimarães

Ferreira

et al. 2010

International Journal of Pediatric Otorhinolaryngology

View full text Add to dashboard Cite

“…These data are consistent with previous studies described by Goodman et al [38] and Xu et al [51] and are different from those observed in previous studies in Brazil, where no significant difference in the prevalence of the infection occurs among boys and girls [26,52]. In the present study, data were gathered from a general population of Japanese Brazilians with similar sociocultural levels and environmental conditions.…”

Section: Discussionsupporting

confidence: 85%

Community-based familial study of Helicobacter pylori infection among healthy Japanese Brazilians

Ito¹,

Oba-Shinjo

Shinjo

et al. 2006

Gastric Cancer

View full text Add to dashboard Cite

“…The results of the present study showed that the overall seroprevalence of H pylori infection was 46.6% in children at age 1-15 years and was 67.5% in adults at age 20-60 years. In different studies, the prevalence of H pylori is variable in children such that it has been reported to be 60% at age 4 years in Ethiopia [11] , 7.5% at age 2-18 years in Czech [12] , 44% at age 6 mo to 17 years in Turkey [13] , 8% at age 1-3 years in USA [14] , 50% at age 1-9 years and 80% at age 10-19 years in Libya [15] , 56% at age 1-14 years in Brazil [16] , 96% at age 1-14 years in Saudi Arbia [17] and 80% at age 1.5-5 years in Bangladesh [18] . Moreover, It has been reported that children in Gambia and Nigeria are almost all infected by H pylori at age of 5 years [19,20] .…”

Section: Discussionmentioning

confidence: 99%

Specific serum immunoglobulin G to H pylori and CagA in healthy children and adults (south-east of Iran)

Jafarzadeh¹,

Rezayati²,

Nemati³

2007

WJG

View full text Add to dashboard Cite

AIM:To evaluate the serologic IgG response to H pylori and CagA across age groups and in healthy children and adults. METHODS:Totally, 386 children aged 1-15 years and 200 adults aged 20-60 years, were enrolled to study. The serum samples of participant were tested for presence of anti-H pylori and anti-CagA IgG by using ELISA method. RESULTS:The seroprevalence of H pylori in adults was significantly higher than that observed in children (67.5% vs 46.6%; P < 0.000003). In children, the seropositivity rate in males (51.9%) was significantly (P < 0.05) higher than that observed in females (41.7%). The prevalence of serum anti-CagA antibody was 72.8% and 67.4% in infected children and adults, respectively. The mean titer of serum anti-CagA antibodies was significantly higher among children in comparison to adults (64.1 Uarb/mL vs 30.7; P < 0.03). In infected children and adults the prevalence of serum anti-CagA antibody was higher in males compared to females (78.4% vs 66.3%; P = 0.07 and 75.6% vs 54.71%; P < 0.04, respectively). The age-specific prevalence of anti-H pylori and anti-CagA antibody (in infected subjects) was 37.6% and 59.57% at age 1-5 years, 46.9% and 75% at age 6-10 years, 54.9% and 79.45% at age 11-15, 59.01% and 83.33% at age 20-30 years, 66.6% and 60.52% at age 31-40 years, 73.46% and 63.88% at age 41-50 years and 75.75% and 60% at age 51-60 years with mean titer of anti-CagA antibody of 75.94, 63.32, 57.11, 52.06, 23.62, 21.52 and 21.80 Uarb/mL, respectively. There was significant difference between mean serum anti-CagA antibody in age subgroups (P < 0.001). CONCLUSION:These results showed that anti-H pylori and anti-CagA antibodies were common in the children and adults. The H pylori -specific antibodies influenced by age and sex of subjects. Moreover, it seems that males are more susceptible to infection with CagA + strains compared to females. The seroprevalence of anti-CagA antibody was increased with age, up to 30 years and then decreased. It was also found that the magnitude of the IgG response to CagA decreased with advanced age.

show abstract

Prevalence of Helicobacter pylori infection in children from an urban community in north-east Brazil and risk factors for infection

Cited by 51 publications

References 18 publications

Helicobacter pylori colonization of the adenotonsillar tissue: Fact or fiction?

Helicobacter pylori colonization of the adenotonsillar tissue: Fact or fiction?

Community-based familial study of Helicobacter pylori infection among healthy Japanese Brazilians

Specific serum immunoglobulin G to H pylori and CagA in healthy children and adults (south-east of Iran)

Contact Info

Product

Resources

About