Prevalence of Helicobacter Pylori Infection and Associated Factors Among Gastritis Patents in Yekatit 12 Teaching Hospital Addis Ababa Ethiopia

Abstract

Introduction: Helicobacter pylori colonize the stomach of about ~50% of the world’s human population and infection is more in clients with dyspeptic conditions and its associated with the severity of gastritis. The present study revealed that the magnitude of H. Pylori and burden of the bacterial infection as well as the contribution of H. Pylori for gastritis and also assesses the current prevalence of H. Pylori infection.Objective: To evaluate the prevalence of Helicobacter Pylori infection and associated factors among gastritis patents in Yekatit 12 Hospital.Methodology: An institutional based cross-sectional study was conducted in Yekatit 12 teaching hospital Addis Ababa city, Ethiopia. The participants were those patients come to the hospital for treatment of gastritis and send to the laboratory to confirm Helicobacter pylori infection in the data collection period. A total of 394 participants were interviewed by using a structured pre tested questionnaire. The data were coded and entered into Epi Data 3.1 version , cleaned and exported to version 20, SPSS. Multiple Logistic regression was used to estimate Adjusted (AORs) with a 95% confidence interval (CI) of positive responses to the different risk factors. P-value < 0.05 was considered as significant.Result: The total occurrence of H. Pylori in observers was 25.9%. Regarding income of family, those participants who have less income and living in rural areas were extra prone to be infected with H. Pylori (AOR=5.857, CI 95% = 1.389-24.686, P = 0.016 and AOR=3.663, CI 95% = 1.068-12.557, P =0.039) respectively. Further, the prevalence of study was significant association with participants who had experience of gastrointestinal illness, mouth to mouth kissing, unable to hand wash regularly before meal and after latrine used (AOR=4.270, 95%CI=1.785-10.21, P=0.01, AOR=53.085, 95%CI=16.185-174.114, P=0.000, AOR=7.316, 95%CI=1.944-27.536, P=0.003, AOR=3.374, 95%CI=1.024-11.114, P=0.046) respectively.Conclusion and recommendation: The finding shows that H. Pylori infection was significantly associated with occupational status,gender, smoking tobacco and hand washing regularly before meal and after toilet. I recommend making clean and saving the work place; regular hand wash, before food preparation, before feeding and after latrine. A health professional should give health education by using different media about the transition and health biro also should give emphases.

Sero- and Feco-Prevalence of Helicobacter pylori Infection and Its Associated Risk Factors among Adult Dyspeptic Patients Visiting the Outpatient Department of Adet Primary Hospital, Yilmana Densa District, Northwest Ethiopia

“…It was lower Canadian Journal of Infectious Diseases and Medical Microbiology than studies conducted in Sudan (70%) [26], Sekota (northeast Ethiopia) (64.8%) [52], and Pakistan (66.66%) [53]. In contrast, the fndings of the current study were higher than reports from Debre Tabor (Ethiopia) (34%) [18], Addis Ababa Ethiopia (25.9%) [12], Nepal (17%) [54], Ghana (14.2%) [55], United Arab Emirates (41%) [56], and Iceland (3.4%) [57]. Te diferences in fndings among various studies can be explained by variations in sociodemographic, socioeconomic, behavioral, types of diagnostic kits having diferent sensitivities, and environmental factors, as well as variations in the number of study population.…”

“…Rural residents had 5.55 times higher odds of H. pylori infection than their counterparts in urban areas. A similar study, which was conducted in Assosa (Ethiopia) [58], Alaska, U.S.A. [46], Addis Ababa (Ethiopia) [12], and Pakistan [59], identifed this variable to be signifcantly associated with H. pylori infection. However, studies conducted in Dessie (Ethiopia) [16], Iraq [50], and Egypt [60] showed that residence was not signifcantly associated with H. pylori infection.…”

“…In a meta-analysis study, the overall pooled prevalence of H. pylori infection was found to be 52.2%, with the Somali region having the highest prevalence (71%), followed by the Amhara region with a prevalence of 54.6% [10]. Te prevalence of H. pylori varied across geographical locations in Ethiopia; it was 42.8% in Mizan Aman town, Southwest Ethiopia [11], 72% among gastritis patients attending Yekatit 12 Teaching Hospital of Addis Ababa [12], 47.7% in Bekoji [13], 30.3% in Shashamane, Ethiopia [14], and 65.7% in Ziway, central Ethiopia (65.7%) [15]. Te frequency of H. pylori infection is also very high in the Amhara Regional State, but it is varied in diferent locations in the region.…”

The Burden and Risk Factors of Helicobacter Pylori Infection Among Government Employees Who Clinically Complain of Indigestion but Allergic Diseases in Southeastern Ethiopia: A Multi-Institution Cross-Sectional Study

“…from the hands of the father of Repent was not an independent determinant of H. pylori infection in the patients. However, a previous study from a closer analogy revealed that mouth-to-mouth kissing was an independent predictor of H. pylori infection in patients, 42 as the difference might be due to the smaller sample size of Orthodox Tewahido Christians in the present study. In addition, our study findings disagree with the previous study report from islands of Indonesia, which showed that ethnicity is an independent risk factor for H. pylori infection.…”