Prevalence of Helicobacter pylori infection and atrophic gastritis in Latvia

Abstract

The prevalence of H. pylori infection or atrophy remains high in Latvia. Determining the right cutoff value is critically important for pepsinogen-based atrophy detection in Europe in order to objectively stratify gastric cancer risk.

Pepsinogen Test for the Evaluation of Precancerous Changes in Gastric Mucosa: a Population-Based Study

“…In our study sample, 68.3% of the participants were women, which could be explained by a higher response rate among women (possibly due to more concern about their health) described in other studies as well [12,18]. Nevertheless, the majority of the men had decreased PG levels in comparison to women, similar with previous data [18,29,44].…”

“…It is assumed and also found in several studies [15], that PG test results directly correlate with H. pylori status in patients, based on the fact that H. pylori is the main etiological factor for atrophic changes in the gastric mucosa [5,8,17,18].…”

The TLR-specific adjuvants R-848 and CpG-B endorse the immunological reaction of neonatal antigen-presenting cells

“…Neonatal APCs demonstrate decreased expression of major histocompatibility complex (MHC)-II and costimulatory molecules such as CD40 and CD86 resulting in reduced cytokine production and decreased ability to present antigens to naive CD4+ T cells (8). Moreover, a number of components of the adaptive immune response themselves have been shown to exhibit less activity in neonates (9).…”

Association between Acute Coronary Syndrome and Helicobacter Pylori Chronic Infection? What data mining tells us?

“…In order to describe the involvement of H. pylori in the development of CHD, it is necessary to find the largest number of reliable research studies; big data confirming this relationship. For our knowledge there is no study have used data mining analysis of such big data related ACS and Pylori, that artificial intelligence of Rapid I used in the current study can find the accurate or possible situation associations, hence according to our results only ACS of long duration of intermittent typical chest pain may becaused by Pylori chronic infection [8][9][10][11][12][13][14][15][16][17][18][19][20]. Data mining is the breakthrough in economy, biology, trading, business, astronomy and medicine [21][22][23].…”