Prevalence of healthcare-associated infections in public hospitals in New Zealand, 2021

Grae, Nikki; Singh, Ashvindev; Jowitt, Deborah; Flynn, Andrea; Mountier, Emily; Clendon, Grace; Barratt, Ruth; Gibson, Barbara E.; Williams, Claudia; Roberts, Sally; Morris, Arthur J.

doi:10.1016/j.jhin.2022.10.002

Cited by 4 publications

(5 citation statements)

References 21 publications

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“…CAUTIs represent the most common device-accompanying HAIs, along with ventilatorassociated pneumonia or central-line-associated bloodstream infections [28]. Most of the recent studies focusing on nosocomial infections point out that the incidence of CAUTIs caused by Enterobacterales, particularly Klebsiella spp., has significantly increased [29,30].…”

Section: Discussionmentioning

confidence: 99%

The Impact of Urinary Catheterization on the Antibiotic Susceptibility of ESBL-Producing Enterobacterales: A Challenging Duo

Miftode,

Vâță,

Miftode

et al. 2024

Antibiotics

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Introduction: Antimicrobial resistance (AMR) is currently a growing concern among healthcare providers, underscoring the importance of describing the regional susceptibility profile for common microorganisms that are associated with urinary tract infections (UTIs). This knowledge serves as the foundation for proper empirical therapeutic recommendations tailored to local susceptibility patterns. Results: We found a high prevalence of ESBL-producing strains (36.9%), with Escherichia coli and Klebsiella spp. being the most prevalent isolated bacteria. Among the catheterized patients, Klebsiella spp. emerged as the primary etiology, with a significant correlation between catheterization and Proteus spp. (p = 0.02) and Providencia stuartii (p < 0.0001). We observed significant correlations between urinary catheterization and older age (68.9 ± 13.7 years vs. 64.2 ± 18.1 years in non-catheterized patients, p = 0.026) and with the presence of an isolate with extensive drug resistance (p < 0.0001) or even pandrug resistance (p < 0.0001). Susceptibility rates significantly decreased for almost all the tested antibiotics during the study period. Notably, susceptibility was markedly lower among catheterized patients, with the most pronounced differences observed for carbapenems (59.6% versus 83.4%, p < 0.0001) and aminoglycosides (37.1% versus 46.9%, p = 0.0001). Materials and Methods: We conducted a retrospective study analyzing the susceptibility profiles of 724 extended-spectrum beta-lactamases (ESBL)-producing Enterobacterales isolated from urine cultures. Our focus was on highlighting susceptibility profiles among isolates associated with urinary catheterization and assessing the shifts in the susceptibility rates over time. Conclusions: The constant rise in AMR rates among Enterobacterales presents significant challenges in treating severe infections, particularly among urinary catheterized patients. This trend leaves clinicians with limited or no effective treatment options. Consequently, the development and implementation of personalized treatment protocols are imperative to ensure efficient empirical therapies.

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Section: Discussionmentioning

confidence: 99%

The Impact of Urinary Catheterization on the Antibiotic Susceptibility of ESBL-Producing Enterobacterales: A Challenging Duo

Miftode,

Vâță,

Miftode

et al. 2024

Antibiotics

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“…A t any one time in New Zealand district hospitals, 6.6% of adult patients, or one in every 15 patients, has a healthcare-associated infection (HAI). 1 HAIs impact on a patient's wellbeing, require additional interventions delaying discharge and add to the cost of healthcare. HAIs are associated with increased mortality.…”

Section: Planning and Executing A National Point Prevalence Study: A ...mentioning

confidence: 99%

“…A national summary report, National point prevalence survey of healthcare-associated infections -Tiro Whānau ā-motu mō te maimoa hauroa-mate urutā, was published on the Te Tāhū Hauora website in May 2022 13 and formally published in 2023. 1…”

Section: Data Management and Reportingmentioning

confidence: 99%

“…Using the same team of surveyors, investing time in training and undertaking daily reviews of all suspected HAI cases resulted in high-quality data as evidenced by the high IRR. 1 This should remain the standard for future PPS. However, we under-estimated the resources required for data analysis both in real-time, when the PPS was in progress and upon completion.…”

Section: Lessons Learned and Modification To The Process For Future Ppsmentioning

confidence: 99%

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Planning and executing a national point prevalence study: a blueprint for the future

Grae,

Roberts,

Barratt

et al. 2023

NZMJ

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“…Older adults are susceptible to infections due to comorbidities and impaired immune function [ 1 ]. Lower urinary tract infection (LUTI), an infection of the bladder, is the most common infection among nursing home residents and the second most common infection among community-dwelling and hospitalized older adults [ 2 , 3 ]. Having a LUTI more than three times in a year or more than twice in 6 months is considered recurrent (rLUTI) [ 4 , 5 ].…”

Section: Introductionmentioning

confidence: 99%

Recurrent lower urinary tract infections: more than an infection for older women

GANİDAĞLI,

ÖZTÜRK,

ÖZTÜRK

2023

Turkish Journal of Medical Sciences

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Background/aim Older adults tend to have more urinary tract infections (UTIs). The frequency of recurrent lower urinary tract infections (rLUTIs) increases with age. rLUTIs are associated with long-term chronic effects on geriatric syndromes in older adults. We aimed to investigate possible risk factors that influence rLUTIs in older adults based on comprehensive geriatric assessment (CGA). Materials and methods This cross-sectional study included 235 older adults admitted to Gaziantep University’s Geriatric Outpatient Clinic between June 1 and November 30, 2022. All patients underwent CGA. The Geriatric Depression Scale (GDS), the European Quality of Life-Five Dimension (EQ-5D) questionnaire, the Pittsburgh Sleep Quality Index (PSQI), the Katz Index of Activities of Daily Living (ADL), the Lawton and Brody Index of Instrumental Activities of Daily Living (IADL), and the Mini Nutritional Assessment (MNA) tool were,administered. Handgrip strength (HGS) and gait speed were also measured, and the number of falls in the last year was recorded. Results The mean age of the participants was 72.8 ± 6.8 years and 61.3% were female. Sixty-four patients had rLUTIs. The rLUTI group had higher frequencies of sarcopenia, hypertension, and diabetes; higher numbers of comorbidities and medications; higher GDS and PSQI scores; and more reported falls. They had lower ADL, MNA, EQ-5D, and gait speed scores. HGS was found to be lower in women with rLUTIs. Higher numbers of comorbidities and GDS scores and lower HGS were independent predictors of rLUTIs in women (p = 0.011, OR: 1.75; p = 0.018, OR: 1.14; and p = 0.042, OR: 0.91, respectively). Conclusion We revealed that decreased HGS, higher GDS, and the number of comorbidities in older women were independent risk factors for rLUTIs. Our findings offer a new perspective on the importance of CGA in diagnosing and preventing rLUTIs.

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Prevalence of healthcare-associated infections in public hospitals in New Zealand, 2021

Cited by 4 publications

References 21 publications

The Impact of Urinary Catheterization on the Antibiotic Susceptibility of ESBL-Producing Enterobacterales: A Challenging Duo

The Impact of Urinary Catheterization on the Antibiotic Susceptibility of ESBL-Producing Enterobacterales: A Challenging Duo

Planning and executing a national point prevalence study: a blueprint for the future

Recurrent lower urinary tract infections: more than an infection for older women

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