Prevalence of HCV-RNA-Positive Patients in a Dialysis Unit in Germany

Cardoso, M. da Silva; Koerner, Michael M.; Epple, S.; Kramer, Roderick; Bundschu, D; Kubanek, B

doi:10.1159/000188323

Cited by 4 publications

(1 citation statement)

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“…This prevalence is significantly higher than those of studies performed in other countries: prevalence figures as low as 3-6.1 % have been reported in The Netherlands (Keur et ai., 1997;Schneeberger et ai., 1993) and as high as 42% in countries like Japan and Saudi-Arabia (Jemni et ai., 1994;Jadoul et ai., 1993;da Silva Cardoso et al, 1994).…”

Section: Resultsmentioning

confidence: 99%

Prevalence of Hepatitis C Virus Infection Among Haemodialysis Patients in West Java, Indonesia

et al. 2003

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Section: Resultsmentioning

confidence: 99%

Prevalence of Hepatitis C Virus Infection Among Haemodialysis Patients in West Java, Indonesia

et al. 2003

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Histopathological Impacts of Hepatitis Virus Infection in Hemodialysis Patients: Should Liver Biopsy Be Performed Before Renal Transplantation?

Özdoğan¹,

Özgür²,

Gür³

et al. 1997

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To evaluate the histologic changes in the livers of renal transplant candidates who were infected with hepatitis viruses, we performed a percutaneous liver biopsy in each of 74 regular hemodialysis patients. Forty percent of them were seropositive for the antibody to hepatitis C virus (anti-HCV) whereas 29.7% had anti-HCV and antibody to hepatitis B surface antigen (antiHBs) concomitantly. Seven (9.5%) were seropositive for only hepatitis B surface antigen HBsAg. Histopathological examination revealed that 30% of patients had chronic active hepatitis (CAH), 11% had chronic persistent hepatitis (CPH), and 3% displayed histopathological evidence of cirrhosis. Eleven of 22 patients with CAH were positive for only anti-HCV, and 2 of 22 were positive for only HBsAg. One patient had HBsAg and anti-HCV together, and 8 of 22 had anti-HBs and anti-HCV concomitantly. None of the anti-HBs positive patients exhibited abnormal histopathological changes. We found no statistically significant difference in histopathological findings between the HBsAg positive and anti-HCV positive patients. As 32 of 74 patients (43%) had some degree of chronic liver disease, we concluded that it is prudent to evaluate liver histology in HBsAg and anti-HCV seropositive renal transplant candidates before transplantation.

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Soroprevalência da hepatite C em pacientes hemodialisados

Mello

Melo-Júnior

Albuquerque

et al. 2007

Rev. Soc. Bras. Med. Trop.

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The objectives of this study were to estimate the serum prevalence of hepatitis C virus (HCV) infection in a dialysis center in the greater Recife region, and to correlate HCV serum positivity with some risk factors. Analyses were performed on 250 patients of both sexes, with ages ranging from 17 to 92 years old. Epidemiological data on these patients were obtained in order to determine the risk factors for this infection. Anti-HCV antibodies were investigated using fourth-generation ELISA. Statistically significant associations (p<0.05) were observed in relation to the risk factors of hemodialysis duration, number of blood component transfusions and time taken for transfusions. The prevalence was low (8.4%) in relation to other Brazilian studies. However, more studies in other centers are needed in order to estimate the real prevalence of HCV infection among patients undergoing hemodialysis in the State of Pernambuco.

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Prevalence of HCV-RNA-Positive Patients in a Dialysis Unit in Germany

Cited by 4 publications

References 0 publications

Prevalence of Hepatitis C Virus Infection Among Haemodialysis Patients in West Java, Indonesia

Prevalence of Hepatitis C Virus Infection Among Haemodialysis Patients in West Java, Indonesia

Histopathological Impacts of Hepatitis Virus Infection in Hemodialysis Patients: Should Liver Biopsy Be Performed Before Renal Transplantation?

Soroprevalência da hepatite C em pacientes hemodialisados

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