Prevalence of Glutamate Carboxypeptidase Ii C1561t, Reduced Folate Carrier 1 A80g, and Methionine Synthase A2756g Gene Polymorphisms in Patients With Type 2 Diabetes Mellitus Among South Indians
Abstract:Objective: Glutamate carboxypeptidase II (GCPII), reduced folate carrier 1 (RFC1), and methionine synthase (MTR) genes involved in the folate metabolic pathway may play a key role in the pathogenesis of diabetes and its complications. The present study aimed to investigate the prevalence of genetic polymorphisms of GCPII C1561T, RFC1 A80G, and MTR A2756G in individuals with type 2 diabetes mellitus (T2DM) among South Indians.
Methods: The study subjects consisted of 100 healthy individuals and 200 patien… Show more
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