Prevalence of Fatigue, Pain, and Affective Disorders in Adults With Duchenne Muscular Dystrophy and Their Associations With Quality of Life

Pangalila, Robert; Bos, G.A. van den; Bartels, Bart; Bergen, Michael P.; Stam, Henk J.; Roebroeck, Marij E.

doi:10.1016/j.apmr.2015.02.012

Cited by 100 publications

(122 citation statements)

References 32 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Sbrocchi et al 13 and Takaso et al 15 observed back pain intensity. Pangalila et al 2 and Bray et al 14 observed bodily pain in general. Lager and Kroksmark, 1 Engel et al…”

Section: • Analysis Of Eligible Studiesmentioning

confidence: 99%

“…Other important factors are pain frequency and duration. Some studies conducted only an assessment of pain 1,2,5,6,7,14 . Another three studies analyzed pain at different times: pre and post two years of bisphosphonate therapy 13 ; before surgery and after six weeks, one year, and two years 15 ; and in six-month follow-ups 14 .…”

Section: • Analysis Of Eligible Studiesmentioning

confidence: 99%

“…The largest DMD population investigated was 80 patients 2 . The smallest population was in the Sbrocchi et al study of seven DMD patients 13 .…”

Section: • Analysis Of Eligible Studiesmentioning

confidence: 99%

“…This topic is important for treatment options and understanding the impact of pain on patient compliance and the outcomes of other rehabilitation interventions 1 . Moreover, fatigue, pain, and affective disorders may encourage effective treatment strategy planning by health care providers 2 . Therefore, this study aimed to investigate the relationship between DMD and pain.…”

mentioning

confidence: 99%

“…Duchenne muscular dystrophy (DMD) is an X-linked recessive disorder caused by mutations in the dystrophin gene, leading to the total absence of or an abnormal, but partly functional, dystrophin protein 1,2 . Duchenne muscular dystrophy is characterized by progressive muscle weakness, ambulation loss and premature death 3 .…”

mentioning

confidence: 99%

See 4 more Smart Citations

Pain characterization in Duchenne muscular dystrophy

Silva

Massetti

Monteiro

et al. 2016

Arq. Neuro-Psiquiatr.

View full text Add to dashboard Cite

Duchenne muscular dystrophy (DMD) is an X-linked recessive disorder, characterized by progressive muscle weakness. Historically, pain has not been considered to be a major symptom in DMD. Objective To investigate the relationship between DMD and pain. Methods We conducted a systematic review in Medline/PubMed and BVS (virtual library in health) databases. We searched for articles that showed the terms “Muscular Dystrophy, Duchenne” and “Pain” in all fields. All studies included boys diagnosed with DMD and the occurrence/amount of pain on this population. Results Initially, there were 175 studies. 167 articles were excluded for not meeting the inclusion criteria. The remaining eight eligible studies, involving pain assessment in DMD, were analyzed. Conclusion Pain is a frequent problem in this population and this symptom is potentially tractable. Studies conclude that pain can directly influence the quality of life of this population.

show abstract

“…Sbrocchi et al 13 and Takaso et al 15 observed back pain intensity. Pangalila et al 2 and Bray et al 14 observed bodily pain in general. Lager and Kroksmark, 1 Engel et al…”

Section: • Analysis Of Eligible Studiesmentioning

confidence: 99%

Section: • Analysis Of Eligible Studiesmentioning

confidence: 99%

“…The largest DMD population investigated was 80 patients 2 . The smallest population was in the Sbrocchi et al study of seven DMD patients 13 .…”

Section: • Analysis Of Eligible Studiesmentioning

confidence: 99%

mentioning

confidence: 99%

mentioning

confidence: 99%

See 3 more Smart Citations

Pain characterization in Duchenne muscular dystrophy

Silva

Massetti

Monteiro

et al. 2016

Arq. Neuro-Psiquiatr.

View full text Add to dashboard Cite

show abstract

Difficulties adapting to Nail‐Patella syndrome: A qualitative study of patients' perspectives

Geerts‐Crabbé

Antoine

Brugallé

et al. 2019

Journal of Genetic Counseling

View full text Add to dashboard Cite

Développement embryonnaire et du Métabolisme: du phénotype au génotype et à la Fonction, Abstract Nail-Patella syndrome (NPS) is a genetic disorder generating physical malformations and, in approximately one in three cases, ocular and renal damage. The present research aimed to deeply understand patients' subjective experience with NPS, particularly the aspects of the syndrome that affect patients' adaptation and to propose interventions that can improve genetic and psychological counseling and help patients cope with their condition. Semi-structured interviews of nine people diagnosed with NPS were analyzed using interpretative phenomenological analysis. Results highlighted attempts to look like a person without disabilities by hiding malformations and not telling the truth about symptoms' genetic origin because of patients' poor self-esteem, negative self-cognition, and social isolation experienced from childhood to adulthood. Difficulties of adaptation to physical limits and painwere also identified. The majority of participants who were not diagnosed at birth tended to consider physical symptoms as "birth malformations" without imagining other potential implications until receiving a diagnosis. Despite the diagnosis, the majority continued to minimize the potential complications by considering NPS as a "physical difference" and not adhering to medical surveillance.

show abstract