Prevalence of erectile dysfunction among Greek men with type 2 diabetes mellitus

Papazafiropoulou, Athanasia; Anagnostopoulou, Konstantina; Petropoulou, Konstantina; Μelidonis, Αndreas

doi:10.4103/aam.aam_32_19

Cited by 2 publications

(3 citation statements)

References 5 publications

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“…ED is a general and notable complication in DM [ 4 , 5 , 6 ] and a challenging task to treat as a consequence of its heterogeneous nature [ 1 , 4 , 5 , 6 , 8 , 9 ]. This study provided positive evidence that PRP was a multifunctional treatment for ED in STZ-induced DM rats, including a decrease in mortality of STZ toxicity and hyperglycemia, increase in wound healing of post-surgery, recovery of ICP, smooth muscles atrophy prevention, and nerves regeneration.…”

Section: Discussionmentioning

confidence: 99%

“…In normal penile erection, the healthy nitrergic nerves, endothelium, and smooth muscles are the major components that play a vital role in the process [ 1 ]. Several factors such as drugs and surgery induce ED [ 2 , 3 ], and it has been emphasized as a common chronic complication of diabetes mellitus (DM) [ 4 , 5 , 6 , 7 ]. Recent studies revealed that 52.5% of DM patients have ED, thus implying that more than half of DM patients have sexual complications.…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Intracavernous Injection of Platelet-Rich Plasma Therapy Enhances Erectile Function and Decreases the Mortality Rate in Streptozotocin-Induced Diabetic Rats

Cui

Lee

Chung

et al. 2022

IJMS

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Erectile dysfunction (ED) is an agonizing complication of diabetes mellitus (DM) and it is challenging to treat ED in DM patients. Platelet-rich plasma (PRP) is a unique therapeutic strategy comprising intrinsic growth factors. An attempt was made to explore the potentiality of the PRP treatment in DM-induced ED rats in various groups (control, DM-non-ED, DM-ED, and DM-ED treated with PRP). Streptozotocin (STZ) was used to induce DM in rats. The blood glucose levels of the DM rats were maintained at >300 mg/dl. In the 18-week experiment, survival rate, body weight, intracavernous pressure (ICP) variations, and arterial blood pressure were analyzed. The tissue restoration results were validated by histological, immunofluorescence, and transmission electron microscopic analysis. PRP treatment of DM-ED rats significantly increased all parameters of erectile function compared to pre-treatment of PRP and DM-ED treated with vehicle. The histological results revealed that PRP treatment substantially enhanced the regeneration of myelinated nerves and decreased the atrophy of corporal smooth muscle. Notably, the PRP treatment immensely enhanced the survival rate in post-surgery DM-ED rats. These results indicated certain benefits of PRP treatment in delaying damage and preventing post-surgery complications in DM patients. Hence, PRP treatment is a novel multifactorial strategy for DM-ED patients.

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Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Intracavernous Injection of Platelet-Rich Plasma Therapy Enhances Erectile Function and Decreases the Mortality Rate in Streptozotocin-Induced Diabetic Rats

Cui

Lee

Chung

et al. 2022

IJMS

View full text Add to dashboard Cite

show abstract

“… 20 A more recent Greek study showed that the prevalence of moderate-to-severe and severe ED was 36.5%. 21 The observed variation in prevalence is related to the ED assessment tools and the ED severity classification but most of the above study showed that different degrees of ED are very commonly prevalent in T2D patients.…”

Section: Discussionmentioning

confidence: 91%

Erectile Dysfunction and Depression Prevalence Among Male Patients with Type II Diabetes

Alswat,

Almorgi,

Aljardahi

et al. 2024

JMDH

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Background and Objective Patients with Type 2 Diabetes (T2D) are at substantial risk for developing erectile dysfunction (ED). The primary goal of this study was to assess the prevalence of ED and depression among T2D patients and the associated risk factors. Methods A cross-sectional study was conducted for adult T2D patients who had a routine clinic visit between January–August 2023. Structured questionnaires formed with two validated questionnaires – the International Index of Erectile Function short form (IIEF-5) and Patient Health Questionnaire (PHQ-9) – were used to screen for ED and depression, respectively. Results A total of 478 male patients with T2D with a mean age of 59.2 ± 10.8 years, mostly married, with long standing T2D were included. Hyperlipidemia followed by hypertension were the most reported comorbidities. Of the patients, 61.3% had reported no depression and were less likely to have ED or severe ED ( p <0.001) and more likely to be physically active and to report no smoking ( p <0.0001) when compared to those with depression. Fifty-two percent of the patients reported moderate and severe ED and those were older in age ( p = 0.031), had longer duration of T2D diagnosis ( p = 0.005), were more likely to have any comorbidities ( p <0.05), were less likely to have a university degree and higher income (both p <0.001), were less likely to be on oral hypoglycemic agents (OHA) ( p <0.001), had worse glycemic control parameters ( p = 0.463), were more likely to have positive urine microalbuminuria ( p = 0.019), and were less likely to be physically active ( p = 0.048) when compared to patients with no or milder degree of ED. Conclusion ED is highly prevalent in our study sample, with half of the patients having moderate to severe ED and being more likely to have depression. Older age, long-standing T2D, comorbidities, socioeconomic disadvantage, and sedentary lifestyle were all significantly associated with ED.

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Prevalence of erectile dysfunction among Greek men with type 2 diabetes mellitus

Cited by 2 publications

References 5 publications

Intracavernous Injection of Platelet-Rich Plasma Therapy Enhances Erectile Function and Decreases the Mortality Rate in Streptozotocin-Induced Diabetic Rats

Intracavernous Injection of Platelet-Rich Plasma Therapy Enhances Erectile Function and Decreases the Mortality Rate in Streptozotocin-Induced Diabetic Rats

Erectile Dysfunction and Depression Prevalence Among Male Patients with Type II Diabetes

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