Prevalence of diverticulosis and incidence of bowel perforation after kidney transplantation in patients with polycystic kidney disease

Fernández, Emilio Domínguez; Albrecht, K; Heemann, Uwe; Kohnle, Matthias; Erhard, J.; Stöblen, F.; Eigler, F. W.

doi:10.1111/j.1432-2277.1998.tb00952.x

Cited by 13 publications

(15 citation statements)

References 15 publications

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“…Sharp et al reported that patients with ADPKD have no greater risk of diverticular disease (8). Dominguez Fernandez et al supported this opinion (9). Whether diverticulosis itself is peculiar to ADPKD is controversial.…”

Section: Discussionmentioning

confidence: 99%

Autosomal Dominant Polycystic Kidney Disease Showing Rupture of a Lateral Ventral Hernia Following Paralytic Ileus

Kato¹,

Ubara²,

Tagami³

et al. 2005

Intern. Med.

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We report an 83-year-old Japanese male with autosomal dominant polycystic kidney disease (ADPKD), which was marked by unusually enlarged kidneys, and in whom ileus occurred after administration of procainamide. The bowels became swollen and ruptured the skin and appeared on the outside of the skin. Even after the ileus state was resolved, the projected intestinal tract was not restored due to a large defect of the skin, and ostomy was performed. Abdominal hernia including lateral ventral hernia due to enlarged kidneys may result in perforation of the abdominal wall as well as intestinal wall.

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Section: Discussionmentioning

confidence: 99%

Autosomal Dominant Polycystic Kidney Disease Showing Rupture of a Lateral Ventral Hernia Following Paralytic Ileus

Kato¹,

Ubara²,

Tagami³

et al. 2005

Intern. Med.

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“…25 Perforation occurs more often in the sigmoid colon but can also occur in the midsigmoid region, cecum, transverse colon, and descending colon. 14,26 A right side colon perforation after renal transplant is rare. 6 Half of the patients in the series reported by Puglisi and associates 25 showed the sigmoid colon as the perforation site.…”

Section: Discussionmentioning

confidence: 99%

“…[9][10][11][12][13] Various studies reported that the prevalence of colonic diverticulosis is significantly higher in patients with autosomal dominant polycystic kidney disease (ADPKD) than in the general population or patients on dialysis for other renal diseases. 4,[14][15][16][17][18] Prevalence rates vary from 53.5% to 83%, with the condition attributed to a congenital colonic defect or the secretory action from the renal cysts on the colonic wall. 8 However, the extent of colonic diverticulitis and perforation does not seem to correlate with the primary renal disease.…”

Section: Discussionmentioning

confidence: 99%

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Kakavia

Moris²,

Karatza³

et al. 2016

Exp Clin Transplant

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Results: One patient died from septic shock before any surgery, and 3 patients died during the early postoperative period, resulting in a morality rate of 36.3%. All patients who died had a functioning graft. From the patients who were discharged, the mean follow-up was 16 months (range, 4-32 months). Conclusions: Intestinal perforation after renal transplant is a major and potentially lethal complication. Clinical presentation is usually equivocal, and the transplant surgeon should be highly suspicious when treating a renal transplant recipient with acute abdominal pain, even in cases without other predisposing factors (diverticulitis, ischemic colitis, and so forth), so that this condition could be investigated and unmasked.

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“…The incidence of colon perforations is 1-2% in kidney transplantation patients [10,11]. Diverticulitis is the most common cause [9,12]. Other causes can be ischaemia or CMV colitis [12].…”

Section: Discussionmentioning

confidence: 99%

“…A delay in the diagnosis in patients after transplantation is common, as the symptoms and signs are sparse and often masked by immunosuppression [9]. The incidence of colon perforations is 1-2% in kidney transplantation patients [10,11].…”

Section: Discussionmentioning

confidence: 99%

Perforation of Terminal Ileum as a Rare Complication of an Early Post- Transplant Course

Dedinská¹,

Laca²

2015

J Clin Case Rep

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Perforations of any part of the gastrointestinal tract can occur in transplant patients, although the colon may be the most common site. We analyze the case of a 39-year-old patient after kidney transplantation who suffered perforation of terminal ileum with peritonitis on the 7th day after transplantation. We histologically confirmed presence of a foreign body in the intestinal wall -a rare cause of intestinal perforation in a patient after kidney transplantation. We have not noticed a significant worsening of graft function or development of sepsis mainly because of quick evaluation of the patient's clinical state, prompt surgical intervention and a combined antibiotic treatment. Gastrointestinal perforations have rarely been noted in large studies involving transplant recipients.

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Prevalence of diverticulosis and incidence of bowel perforation after kidney transplantation in patients with polycystic kidney disease

Abstract: Sigmoid perforation due to diverticulitis is a life-threatening complication in the postoperative course of allogenic kidney transplantation.

Cited by 13 publications

References 15 publications

Autosomal Dominant Polycystic Kidney Disease Showing Rupture of a Lateral Ventral Hernia Following Paralytic Ileus

Autosomal Dominant Polycystic Kidney Disease Showing Rupture of a Lateral Ventral Hernia Following Paralytic Ileus

Untitled

Perforation of Terminal Ileum as a Rare Complication of an Early Post- Transplant Course

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