This study aimed to monitor the prevalence of pregnant women using multivitamin supplements in the city of Makkah Al-Mukaramah, and the effect of some factors (educational level, age, household income, number of pregnancies) on women's intake of these nutritional supplements. A cross section study was conducted among 170 women in Makkah Al-Mukaramah region, and the results were analyzed statistically using SPSS statistics (v. 26). The results suggested that there was a significant relation between the prevalence of multivitamin supplements use by pregnant women and both age and number of pregnancies. There was no significant relation between the prevalence of multivitamin supplements use by pregnant women and the educational level or household income. Future studies need to expand the scope in a larger sample size and to include health professional recommendations in relation to nutritional supplements use.