Prevalence of diabetes mellitus and impaired glucose tolerance in a middle-aged Finnish population

Rajala, Ulla; Keinänen‐Kiukaanniemi, Sirkka; Uusimäki, Aira; Reijula, Kari; Kivelä, Sirkka‐Liisa

doi:10.3109/02813439508996765

Cited by 38 publications

(29 citation statements)

References 20 publications

(13 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The prevalence of diabetes among Malays in the current study is higher than prevalence rates reported from the Unite States, the United Kingdom, and other developed countries in the West. [10][11][12] The prevalence of diabetes mellitus in the current study using an alternative definition produced similar results though the prevalence of undiagnosed diabetes was slightly higher.…”

Section: Discussionsupporting

confidence: 85%

Prevalence of Diabetes Mellitus, Glycemic Control, and Associated Factors in a Malay Population in Singapore

Sabanayagam

Shankar

Saw

et al. 2009

Asia Pac J Public Health

View full text Add to dashboard Cite

There is substantial heterogeneity regarding diabetes mellitus prevalence and glycemic control in Asian populations. The authors examined a population-based sample of 3000 adults (52% women) of Malay ethnicity (40-80 years) in Singapore. The age-standardized prevalence of diabetes mellitus was 18.4% (95% confidence interval = 17.0% to 19.8%). Being overweight, presence of hypertension, presence of cardiovascular disease, and family history of diabetes were found to be positively associated with diabetes mellitus. Higher education, employment status, and current smoking were found to be inversely associated with diabetes mellitus. Among those treated for diabetes, 29% achieved the optimal glycemic goal (glycosylated hemoglobin <7%). Lower levels of low-density lipoprotein cholesterol, total cholesterol, and systolic and diastolic blood pressure were associated with good glycemic control. Nearly 1 in 5 middle-aged Malay adults living in a developed Asian society had diabetes mellitus and a substantial proportion had suboptimal glycemic control.

show abstract

Section: Discussionsupporting

confidence: 85%

Prevalence of Diabetes Mellitus, Glycemic Control, and Associated Factors in a Malay Population in Singapore

Sabanayagam

Shankar

Saw

et al. 2009

Asia Pac J Public Health

View full text Add to dashboard Cite

show abstract

“…20 In 1998, altogether 60 subjects of the cohort had clinical diabetes, defined as either diabetes diagnosed by a physician before the baseline or as two elevated blood glucose values (either fasting blood glucose values of X6.1 mmol/l or 2-h OGTT values of X11.1 mmol/l) during this study in 1992-1998. All subjects with clinical diabetes (except one with cancer) and those with impaired glucose tolerance (IGT) on the basis of the 1996-1998 OGTT results were invited to participate in the present study.…”

Section: Methodsmentioning

confidence: 99%

“…20 All of the 1008 subjects born in 1935 and living in Oulu, a city of 100 000 inhabitants, on 1 October 1990, were invited to participate in the study. Altogether 768 subjects attended the OGTTs, and the participation rate was 78%.…”

Section: Methodsmentioning

confidence: 99%

Blood pressure and atherosclerotic plaques in carotid, aortic and femoral arteries in elderly Finns with diabetes mellitus or impaired glucose tolerance

et al. 2004

View full text Add to dashboard Cite

The aim of the study was to evaluate the occurrence of atheromatous plaques in carotid, aortic and femoral arteries, focusing on blood pressure (BP). The study subjects consisted of 65-year-old Finns drawn from a population-based cohort. Ultrasonographic measurements were performed on 54 diabetic subjects, 97 subjects with impaired glucose tolerance (IGT) and 57 normoglycaemic subjects (NGT). High systolic BP (SBP) was defined as X160 mmHg and high diastolic BP as X95 mmHg. High pulse pressure (PP) was defined as the highest tertile (X75 mmHg) of PP and high mean BP (MBP) as the highest tertile (X111 mmHg) of MBP. The prevalence of atheromatous plaques was 77% (160/208) in carotid arteries, 94% (195/208) in aorta and 77% (161/ 208) in femoral arteries. A total of 64% (134/208) of the subjects had plaques in both carotid and femoral arteries, and they were compared with those who had plaques in 0-1 of these arteries. In addition to male gender and long-lasting smoking, the occurrence of plaques in both carotid and femoral arteries were associated with high SBP and high MBP. According to the results of multiple regression analyses, the adjusted odds ratio for plaques in both carotid and femoral arteries was 3.1 (95% CI 1.5-6.5) in subjects with high SBP compared to those with lower SBP. When SBP was replaced by high MBP, the adjusted odds ratio for it was 2.3 (95% CI 1.1-4.8).

show abstract

“…25 All the 1008 subjects born in 1935 and living in Oulu, a city of 100 000 inhabitants, on 1 October 1990, were invited to participate in the study. Altogether, 768 subjects attended the OGTTs, and the participation rate was 78%.…”

Section: Methodsmentioning

confidence: 99%

Associations of blood pressure with carotid intima-media thickness in elderly Finns with diabetes mellitus or impaired glucose tolerance

et al. 2003

View full text Add to dashboard Cite

The aim of the present study was to evaluate the associations of ultrasonographic manifestations of carotid atherosclerosis with systolic (SBP) and diastolic blood pressure (DBP) and pulse pressure (PP) in 65-year-old Finns drawn from a population-based cohort. Carotid ultrasonographic measurements were performed on 54 diabetic subjects, 97 subjects with impaired glucose tolerance (IGT) and 57 normoglycaemic subjects (NGT). The subjects were classified into four quartiles of SBP, DBP and PP. SBP, DBP, PP and the use of antihypertensive drugs increased along with the deterioration of glucose status. The maximal intima-media thickness (IMT) of the common carotid artery (CCA) from the lowest to the highest quartiles of SBP was 0.98 7 0.34, 1.00 7 0.35, 1.03 7 0.29, 1.18 7 0.52 mm (P ¼ 0.038), respectively. SBP was higher (161 7 22 mmHg) in the subjects with severe intimamedia thickening (maximal IMT CCA X1.2 mm) than in those with maximal IMT CCA of o1.2 mm (153 7 20 mmHg) (P ¼ 0.030). DBP and PP tended to be higher in the former than the latter group (DBP: 89 7 9 mmHg vs 86 7 9 mmHg, P ¼ 0.055 and PP: 72 7 18 mmHg vs 67 7 17 mmHg, P ¼ 0.159). The prevalence of severe intima-media thickening was 39% in the subjects in the highest SBP quartile (X170 mmHg) and 20% in the subjects with lower SBP (P ¼ 0.008). In multiple regression analysis, the adjusted OR for severe intima-media thickening was 2.9 (95% CI 1.1-7.9) in the subjects in the highest SBP quartile compared to the subjects with lower SBP. In the present study, high SBP was associated with severe carotid intima-media thickening. We suggest that the results can be generalized to apply to elderly Finnish subjects with DM and IGT, but not to normoglycaemic subjects, on the basis of this study.

show abstract

Prevalence of diabetes mellitus and impaired glucose tolerance in a middle-aged Finnish population

Cited by 38 publications

References 20 publications

Prevalence of Diabetes Mellitus, Glycemic Control, and Associated Factors in a Malay Population in Singapore

Prevalence of Diabetes Mellitus, Glycemic Control, and Associated Factors in a Malay Population in Singapore

Blood pressure and atherosclerotic plaques in carotid, aortic and femoral arteries in elderly Finns with diabetes mellitus or impaired glucose tolerance

Associations of blood pressure with carotid intima-media thickness in elderly Finns with diabetes mellitus or impaired glucose tolerance

Contact Info

Product

Resources

About