Prevalence of dental enamel defects in celiac patients with deciduous dentition: a pilot study

Páez, E. Ortega; Lafuente, P. Junco; García, Pilar Baca; Lozano, J. Maldonado; Calvo, Juan

doi:10.1016/j.tripleo.2008.01.022

Cited by 27 publications

(18 citation statements)

References 10 publications

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“…The majority only had Grade I defects, however, in a small number, the defects were severe (Grades 3 and 4). Our findings are similar to those reported elsewhere (6,16), and in contrast to those reported by Aine who found most Finnish children had Grade 2 defects with 30% having Grade 4 defects. The reasons for these differences is not clear, however, it could be related to the fact that children in Aine's study were generally older at the time of diagnosis of their CD.…”

Section: Discussionsupporting

confidence: 93%

A Comparison of the Prevalence of Dental Enamel Defects and Other Oral Findings in Children with and Without Celiac Disease

et al. 2018

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Background: Dental enamel defects and other oral manifestations are reported to occur more commonly in children with celiac disease (CD). Our aim was to investigate the frequency and distribution of enamel defects and dental caries, and the presence of other oral findings in children with CD and to compare them to a group of children without CD. Methods: From 200 index cases with CD, 65 cases aged between three to 16 years accepted to participated in the study after an oral explanation for the parents. In addition, 60 healthy, age, and sex matched subjects without CD were chosen as control group. Enamel defects were classified according to the Aine criteria and dental caries was recorded by calculation of DMFT/dmft indices. The presence of other oral findings, such as aphthous ulcers and xerostomia, were recorded. Chi-Square test and Mann-Whitney test were used for comparison of data. P values < 0.05 were considered statistically significant. Results: A total of 65 children with CD and 60 non-CD subjects were studied. There were significantly more enamel defects in children with CD compared to the control group (P = 0.01). Grade I was the most common enamel defect in both groups. Symmetric and non-specific enamel defects were observed in 45% and 14% of CD subjects and in 12% and 12% of the control group (P = 0.001). The location of enamel defects in permanent and deciduous teeth was more prominent in anterior teeth with a coronal distribution involving the incisor and middle parts of the teeth. The dmft index was significantly higher in the control group compared to the CD group (P = 0.003). With the exception of xerostomia, there was no difference in other oral manifestations between groups. Conclusions: Enamel defects are more common in children with CD compared to those without this disease. This finding should alert health care providers to consider testing for CD.

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Section: Discussionsupporting

confidence: 93%

A Comparison of the Prevalence of Dental Enamel Defects and Other Oral Findings in Children with and Without Celiac Disease

et al. 2018

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“…Children with coeliac disease are also at risk to enamel hypomineralization due to malabsorption and mineral deficiencies associated with gut enteropathy from gluten intolerance . Disruption of mineralization pathways as a result of chronic renal and liver disease also places affected children at risk for enamel defects .…”

Section: Developmental Defects Of Enamelmentioning

confidence: 99%

Developmental defects of enamel and dentine: challenges for basic science research and clinical management

Seow

2013

Australian Dental Journal

200

177

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Abnormalities of enamel and dentine are caused by a variety of interacting factors ranging from genetic defects to environmental insults. The genetic changes associated with some types of enamel and dentine defects have been mapped, and many environmental influences, including medical illnesses that can damage enamel and dentine have been identified. Developmental enamel defects may present as enamel hypoplasia or hypomineralization while dentine defects frequently demonstrate aberrant calcifications and abnormalities of the dentine-pulp complex. Clinically, developmental enamel defects often present with problems of discolouration and aesthetics, tooth sensitivity, and susceptibility to caries, wear and erosion. In contrast, dentine defects are a risk for endodontic complications resulting from dentine hypomineralization and pulpal abnormalities. The main goals of managing developmental abnormalities of enamel and dentine are early diagnosis and improvement of appearance and function by preserving the dentition and preventing complications. However, despite major advances in scientific knowledge regarding the causes of enamel and dentine defects, further research is required in order to translate the knowledge gained in the basic sciences research to accurate clinical diagnosis and successful treatment of the defects.Keywords: Enamel, dentine, hypoplasia, hypomineralization.Abbreviations and acronyms: AI = amelogenesis imperfecta; BSP = bone sialoprotein; CPP-ACP = calcium phosphopeptide-amorphous calcium phosphate; DMP1 = dentine matrix protein 1; DSPP = dentine sialophosphoprotein; EB = epidermolysis bullosa; EDI = Enamel Defects Index; FGF = fibroblast growth factor; MEPE = matrix extracellular phosphorylated glycoprotein; MIH = molar-incisor hypomineralization; OPN = osteopontin; TDO = tricho-dento-osseous.

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“…Besides prematurity of birth, coeliac disease is another condition where malabsorption and mineral deficiencies resulting from the gut enteropathy caused by gluten intolerance can cause DDE. Enamel defects are commonly encountered in coeliac disease to the extent that they have been proposed as a possible diagnostic sign of ‘silent’ coeliac disease in children . Scanning electron microscopic analysis of hypoplastic teeth from children with coeliac disease has provided evidence that the enamel is less mineralized as well as more irregular in its organization .…”

Section: Introductionmentioning

confidence: 99%

Developmental enamel defects in the primary dentition: aetiology and clinical management

Salanitri

Seow

2013

Australian Dental Journal

140

133

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Developmental enamel defects, presenting as enamel hypoplasia or opacities are caused by damage or disruption to the developing enamel organ as a result of inherited and acquired systemic conditions. The high prevalence of these defects in the primary dentition demonstrates the vulnerability of the teeth to changes in the pre-and postnatal environment. The presence of enamel hypoplasia increases the risk of primary teeth to early childhood caries and tooth wear as the defective enamel is thinner, more plaque retentive and less resistant to dissolution in acid compared to normal enamel. The purpose of this paper was to critically review the aetiology and clinical complications of developmental enamel defects in the primary dentition and propose recommendations for the clinical management of affected teeth.Keywords: Enamel hypoplasia, enamel opacities, early childhood caries, primary dentition.Abbreviations and acronyms: CMV = cytomegalovirus; CPP-ACP = casein phosphopeptide amorphous calcium phosphate; DDE = developmental defects of enamel; EEC = early childhood caries; HAS-ECC = hypoplasia-associated ECC; MIH = molar-incisor hypoplasia; SEM = scanning electron microscopic.

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Prevalence of dental enamel defects in celiac patients with deciduous dentition: a pilot study

Cited by 27 publications

References 10 publications

A Comparison of the Prevalence of Dental Enamel Defects and Other Oral Findings in Children with and Without Celiac Disease

A Comparison of the Prevalence of Dental Enamel Defects and Other Oral Findings in Children with and Without Celiac Disease

Developmental defects of enamel and dentine: challenges for basic science research and clinical management

Developmental enamel defects in the primary dentition: aetiology and clinical management

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