Prevalence of delusional disorder among psychiatric inpatients: data from the German hospital register

Soyka, Michael; Zingg, Christina; Baumgärtner, Gerd

doi:10.2217/npy.11.43

Cited by 3 publications

(2 citation statements)

References 27 publications

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“…[ 10 ] High cortisol release associated with delirium has been reported in stroke[ 11 ] in postcardiac surgery,[ 12 ] in the elderly patients with hip fracture,[ 13 ] in psychological depression, and in Cushing’s syndrome. [ 14 ]…”

Section: Introductionmentioning

confidence: 99%

To evaluate serum cortisol levels in patients with alcohol withdrawal delirium v/s patients with delirium due to any other disorder

Sibia,

Singh,

Joshi

et al. 2023

Journal of Family Medicine and Primary Care

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A BSTRACT Background: Delirium is an acute confusional state characterized by changes in the mental status, level of consciousness, impaired cognition, and inattention. It can develop within hours or days. Cortisol release from the hypothalamic–pituitary–adrenal axis (HPA) is vital for the host survival in stress. Biomarkers are used as an indicator of pathogenic processes or to assess the responses to a therapeutic intervention. To improve delirium recognition and care, investigators have identified possible biomarkers that may help in diagnosing individuals with delirium, assessing the severity of delirium. Cortisol has been suggested as biomarker for the diagnosis of delirium. Aims and Objectives: To evaluate and compare levels of serum cortisol in patients with alcohol withdrawal delirium with delirium due to other disorders. Materials and Methods: It was a cross-sectional prospective observational study. A total of 30 patients in Group A and 32 in Group B were included. The participants were evaluated based on delirium rating scale (DRS). Results: It was seen that in alcohol withdrawal delirium group, there was significant positive correlation between DRS score and serum cortisol level, i.e., with increase in DRS score, there was increase in serum cortisol levels and vice versa. Conclusion: Serum cortisol levels are associated and directly correlate with the occurrence and severity of delirium. Further studies are needed to elucidate the implications of this association for diagnosis and treatment.

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Section: Introductionmentioning

confidence: 99%

To evaluate serum cortisol levels in patients with alcohol withdrawal delirium v/s patients with delirium due to any other disorder

Sibia,

Singh,

Joshi

et al. 2023

Journal of Family Medicine and Primary Care

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“…DD is a rare mental disorder that accounts for 0.5% of psychiatric hospital admissions [3], with an estimated prevalence in general population of 0.24% [4]. Delusions in DD may present with similar characteristics as in SZ but have been found to be more severe and comprising higher levels of conviction than in SZ [5]; jealousy and somatic delusions as topics are more prominent in DD than in SZ [5].…”

Section: Introductionmentioning

confidence: 99%

Aberrant Gray Matter Volume and Cortical Surface in Paranoid-Type Delusional Disorder

et al. 2020

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Introduction: Delusions are core symptoms of schizophrenia-spectrum and related disorders. Despite their clinical relevance, the neural correlates underlying such phenomena are unclear. Recent research suggests that specific delusional content may be associated with distinct neural substrates. Objective: Here, we used structural magnetic resonance imaging to investigate multiple parameters of brain morphology in patients presenting with paranoid type delusional disorder (pt-DD, n = 14) compared to those of healthy controls (HC, n = 25). Methods: Voxel-and surface-based morphometry for structural data was used to investigate gray matter volume (GMV), cortical thickness (CT) and gyrification. Re-sults: Compared to HC, patients with pt-DD showed reduced GMV in bilateral amygdala and right inferior frontal gyrus. Higher GMV in patients was found in bilateral orbitofrontal and in left superior frontal cortices. Patients also had lower CT in frontal and temporal regions. Abnormal gyrification in patients was evident in frontal and temporal areas, as well as in bilateral insula. Conclusions: The data suggest the presence of aberrant GMV in a right prefrontal region associated with belief evaluation, as well as distinct structural abnormalities in areas that essentially subserve processing of fear, anxiety and threat in patients with pt-DD. It is possible that cortical features of distinct evolutionary and genetic origin, i.e. CT and gyrification, contribute differently to the pathogenesis of pt-DD.

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Data, diagnoses, and interventions addressing the nursing focus “delusion”: A scoping review

Gonçalves

Sampaio

Sequeira

et al. 2019

Perspect Psychiatr Care

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Prevalence of delusional disorder among psychiatric inpatients: data from the German hospital register

Cited by 3 publications

References 27 publications

To evaluate serum cortisol levels in patients with alcohol withdrawal delirium v/s patients with delirium due to any other disorder

To evaluate serum cortisol levels in patients with alcohol withdrawal delirium v/s patients with delirium due to any other disorder

Aberrant Gray Matter Volume and Cortical Surface in Paranoid-Type Delusional Disorder

Data, diagnoses, and interventions addressing the nursing focus “delusion”: A scoping review

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