Prevalence of Cryptosporidium in Children with Diarrhoea in North Indian Tertiary Care Hospital

Tahira, Farhat; Khan, Haris M.

doi:10.4172/jcmhe.1000136

Cited by 6 publications

(9 citation statements)

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“…Cryptosporidiosis is reported worldwide but its prevalence varies widely in different parts of the world [16]. The present study is the first record of cryptosporidiosis among children in Wasit Province, Iraq.…”

Section: Discussionmentioning

confidence: 88%

Prevalence of Cryptosporidium Parvum among Children in Iraq

Rahi¹,

Ali²,

Al-Charrakh³

2013

AJLS

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Abstract:Cryptosporidiosis is a parasitic disease caused by an apicomplexan protozoa of. Cryptosporidium parvum is the specific infective agent in human . The present study aimed to search for the presence of C. parvumand to determine the prevalence of this parasite among children in Kut city, Iraq. Six hundred stool samples were collected from children less than twelve years old from October 2011 to May 2012. Stool samples were inspected by modified Ziehl-Neelsen acid fast stain and ELISA. Results indicated that 203 cases gave positive results (33.83 %) and 397 cases gave negative results (66.17%) with Ziehl-Neelsen acid fast stain . The higher infection, 115 (19.17%) appeared in age (<1) year while the lower infection 37 (6.17%) appeared in age (1-6) years. There was association between anemia 66.01% (134/203), Packed Cell Volume (PCV) 66.01% (134/203), White Blood Cells Count (WBC's) 66.01% (134/203) that showed increase in number, and infection with cryptosporidiosis, respectively. The high percentage of positive cases (100%) was recorded in microscopic examination compared to 72.5% (129/178) of positive cases detected by ELISA assay. The present study is the first record of cryptosporidiosis among children in Wasit Province, Iraq. It demonstrated clearly a high prevalence rate of C. parvum among children of less than 12 years old in Iraq. ELISA technique will be of great value in the rapid and accurate diagnosis of C. parvum in human fecal materials.

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Section: Discussionmentioning

confidence: 88%

Prevalence of Cryptosporidium Parvum among Children in Iraq

Rahi¹,

Ali²,

Al-Charrakh³

2013

AJLS

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“…Therefore, a low infectious dose is sufficient to establish the infection, and since repeated exposure to the parasite could confer some sort of immunity against the infection, older children are more protected. 16 Age was also found to be an important factor affecting the incidence of rotavirus gastroenteritis. 17 We found that rotavirus infection was significantly (p<0.05) higher among children younger than 3 years of age comparing with children older than 3 years of age (70.4% vs 18.3%).…”

Section: Discussionmentioning

confidence: 99%

<em>Cryptosporidium</em> spp. and rotavirus gastroenteritis and change of incidence after rotavirus vaccination among children in Raparin Pediatrics Hospital, Erbil, Iraq

Azeez¹,

Alsakee

2017

Med J Indones

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ABSTRAK (11,7%). Puncak infeksi terjadi selama musim semi 9 (65,9% vs 14,1%, p<0,05). ,5%). Tingkat deteksi rotavirus (32,0%) sedikit lebih tinggi pada laki-laki (34,4% vs 30,0%) dan anak usia 1 sampai 3 tahun (39,3%). Tingkat deteksi tertinggi (38,6%) terjadi selama musim dingin (Januari dan Februari). Infeksi lebih tinggi bermakna pada anak yang tidak divaksin Kesimpulan: Insidens cryptosporidiosis mengalami penurunan tetapi gastroenteritis akibat rotavirus cukup banyak terjadi pada anak-anak di Erbil. Vaksin rotavirus menurunkan insidens infeksiakibat rotavirus secara bermakna. ABSTRACTBackground: Watery diarrhea is the most common medical problem among infants and young children, caused by different microbial etiology including Cryptosporidium spp. and rotavirus, which are usually misdiagnosed in conventional stool test. This study aimed to investigate the incidence of Cryptosporidium and rotavirus gastroenteritis among children in Erbil as well as evaluate the efficacy of rotavirus vaccination procedure applied in Erbil.

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“…Evaluation of the true ranking of one diagnostic method over another for decision making, should be based on the laboratory utility instead of being limited to the diagnostic yields (sensitivity and specificity) (Tahira et al 2012). The Multi-attribute utility theory (Mac Pherson and Mc Queen 1993) and analytical hierarchy process (Dolan 1989) that identify, characterize and combine different parameters that were used in the present study to evaluate the true ranking of the used diagnostics for detection of Cryptosporidium.…”

Section: Discussionmentioning

confidence: 99%

Laboratory utility of coproscopy, copro immunoassays and copro nPCR assay targeting Hsp90 gene for detection of Cryptosporidium in children, Cairo, Egypt

et al. 2014

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Cryptosporidium is a significant cause of diarrhea worldwide especially in children. Infection may end fatally in immunocompromised patients. Multi-attribute analysis was used to determine the lab utility of 4 diagnostics; coproscopy of AF stained fecal smear, fecal immunoassays by ICT and ELISA and copro-nPCR assay targeting Hsp90 gene, for detection of Cryptosporidium in stool of 250 Egyptian children (150 diarrheic and 100 nondiarrhaeic children). Also, to determine Cryptosporidium molecular prevalence. Cryptosporidium was an important enteric pathogen among both diarrheic and non-diarrheic study children with a clearly high prevalence of 16.4 % (n = 41). Conventional methods had perfect specificity (100 %) but couldn't be used as a consistent single detection method due to their lowered sensitivities. Multiattribute analysis ranked nPCR the highest test for lab use. Being the test with the best diagnostic yield, nPCR is a reliable diagnostic test and is going to replace conventional methods for reliable detection of Cryptosporidium.

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Prevalence of Cryptosporidium in Children with Diarrhoea in North Indian Tertiary Care Hospital

Cited by 6 publications

References 0 publications

Prevalence of Cryptosporidium Parvum among Children in Iraq

Prevalence of Cryptosporidium Parvum among Children in Iraq

<em>Cryptosporidium</em> spp. and rotavirus gastroenteritis and change of incidence after rotavirus vaccination among children in Raparin Pediatrics Hospital, Erbil, Iraq

Laboratory utility of coproscopy, copro immunoassays and copro nPCR assay targeting Hsp90 gene for detection of Cryptosporidium in children, Cairo, Egypt

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