Prevalence of Coronary Slow Flow in Patients Undergoing Coronary Angiogram in a Large Teaching Hospital

Jesuthasan, Lalith S.B.; Beltrame, John F.; Marwick, Thomas H.

doi:10.1016/j.hlc.2009.05.275

Cited by 5 publications

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“…Data from Australia report that the coronary slow fl ow phenomenon (CSFP) is seen in 1 % of the total diagnostic angiograms, based upon reports from the cardiologist performing the procedure [ 9 ] . More recent data from Australia Based on data from Beltrame [ 37 ] Other ( suggest the CSFP is prevalent in 3 % of patients with NCA [ 47 ] . Australian fi ndings are based upon the de fi nition of three or more beats to opacity the left anterior descending artery.…”

Section: Cardiac Causesmentioning

confidence: 99%

Epidemiology of Cardiac Syndrome X and Microvascular Angina

Tavella

Eslick

2013

Chest Pain With Normal Coronary Arteries

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Abbreviations ACSAcute coronary syndrome CAD Coronary artery disease CHD Coronary heart disease CSFP Coronary slow fl ow phenomenon GUSTO Global utilization of streptokinase and t-PA for occluded coronary arteries MI Myocardial infarction NCA Normal coronary angiography TIMI Thrombosis in myocardial infarction WISE Women's ischemia syndrome evaluation AbstractChest pain and normal coronary angiography is seen in up 30 % of patients undergoing the investigation. Despite its notable prevalence, the epidemiology of the condition remains poorly documented. Since the turn of the twentieth century, researchers have been baf fl ed by "unmistakable" angina in the absence of coronary artery disease. Curiosity as to the cardiac aetiology of this chest pain became the focus of several key studies investigating the clinical and haemodynamic features of patients with normal coronary angiography. From these early fi ndings, the cardinal features of three speci fi c disorders associated with normal coronary angiography were established -Cardiac Syndrome X, Microvascular Angina and more recently, the Coronary Slow Flow Phenomenon. Although ambiguity in the literature exists, it is likely that an 'ischemic' mechanism for the chest pain in these patients is explained by coronary microvascular dysfunction. It also now understood that despite the absence of signi fi cant coronary artery disease, the outcomes of patients are not entirely favourable, with studies suggesting a frequent persistence of chest pain, and increased risk of cardiac events, particularly among women. This chapter will review the available epidemiological data on patients with chest pain and normal coronary angiography, and the clinical features and possible aetiological explanations for the speci fi c coronary microvascular disorders. KeywordsNormal coronary angiography • Prinzmetal's angina • Coronary heart disease • Myocardial ischemia • Cardiac syndrome X • Microvascular angina • Coronary slow fl ow pheonemon

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Section: Cardiac Causesmentioning

confidence: 99%

Epidemiology of Cardiac Syndrome X and Microvascular Angina

Tavella

Eslick

2013

Chest Pain With Normal Coronary Arteries

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“…Coronary slow flow (CSF) is an angiographic finding characterized by delayed distal vessel opacification of nonobstructive epicardial coronary arteries [ 1 ]. CSF is not uncommon and its incidence is reported to range between 1% and 3% in different populations undergoing coronary angiography [ 2 , 3 ]. CSF has long been known by interventional cardiologists and usually appears in young male smokers [ 4 ].…”

Section: Introductionmentioning

confidence: 99%

The Systemic Immune-Inflammation Index May Predict the Coronary Slow Flow Better Than High-Sensitivity C-Reactive Protein in Patients Undergoing Elective Coronary Angiography

Karaüzüm

Hanci

et al. 2022

Cardiology Research and Practice

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Background and Objectives. The coronary slow flow (CSF) is an angiographic finding characterized by delayed opacification of nonobstructive epicardial coronary arteries. Chronic inflammation has been suggested to be mainly responsible for the underlying mechanism of CSF. The systemic immune-inflammation index (SII) is a relatively novel inflammation-based biomarker, derived from counts of peripheral neutrophils, platelets, and lymphocytes, and has been shown to predict clinical outcomes in various malignancies and cardiovascular diseases. The aim of this study is to evaluate the relationship between SII and CSF. Methods. A total of 197 patients (102 patients with CSF; 95 patients with normal coronary flow) were included in this retrospective study. Clinical and angiographic characteristics of patients were obtained from hospital records. Results. Patients with CSF had higher SII, neutrophil-to-lymphocyte ratio (NLR), platelet-to-lymphocyte (PLR), and high-sensitivity C-reactive protein (hsCRP) levels compared with the control group. Body mass index ( p = 0.022 , OR 1.151, 95% CI 1.121–1.299), low-density lipoprotein ( p = 0.018 , OR 1.028, 95% CI 1.005–1.052), hsCRP ( p = 0.044 , OR 1.161, 95% CI 1.004–1.343), and SII ( p < 0.001 , OR 1.015, 95% CI 1.003–1.026) were independent predictors of CSF in the multivariable analysis. The optimal cutoff value of SII in predicting CSF was >877 in ROC curve analysis ( p < 0.001 , AUC = 0.892, 95% CI 0.848–0.936). This cutoff value of SII predicted the CSF with a sensitivity of 71.5% and specificity of 92.4%. Spearman correlation analysis showed a positive correlation between the mean TFC value and PLR, NLR, hsCRP, and SII. Conclusions. SII may be used as a better indicator for the prediction of CSF than hsCRP.

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The Coronary Slow Flow Phenomenon

Beltrame

Ganz

2013

Chest Pain With Normal Coronary Arteries

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Prevalence of Coronary Slow Flow in Patients Undergoing Coronary Angiogram in a Large Teaching Hospital

Cited by 5 publications

References 0 publications

Epidemiology of Cardiac Syndrome X and Microvascular Angina

Epidemiology of Cardiac Syndrome X and Microvascular Angina

The Systemic Immune-Inflammation Index May Predict the Coronary Slow Flow Better Than High-Sensitivity C-Reactive Protein in Patients Undergoing Elective Coronary Angiography

The Coronary Slow Flow Phenomenon

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