Prevalence of COPD in Copenhagen

Fabricius, P. G.; Løkke, Anders; Marott, Jacob Louis; Vestbo, Jørgen; Lange, Peter

doi:10.1016/j.rmed.2010.09.019

Cited by 53 publications

(59 citation statements)

References 35 publications

(18 reference statements)

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“…Th ese diff erences may refl ect not only real diff erences, but may at least in part be due to diff erences in methods and diagnostic tools, further, to diff erences in smoking patterns, environmental and other exposures and to differences in the genetic background. In the age >50 years, the prevalence of COPD in our study was 14.5% (men 23.5%; women 6.8%), which is similar to estimates of prevalence in Europe, for instance 14.3% in the age >45 years in northern Sweden (23) and 17.4% in Copenhagen in the age >35 years (7).…”

Section: Discussionsupporting

confidence: 88%

Prevalence of COPD by Disease Severity in Men and Women in Northern Vietnam

Lâm

Ekerljung

Rönmark³

et al. 2014

COPD: Journal of Chronic Obstructive Pulmonary Disease

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The prevalence of COPD and its risk factor pattern varies between different areas of the world. The aim of this study was to investigate the prevalence of COPD by disease severity in men and women and risk factors for COPD in northern Vietnam. From all 5782 responders to a questionnaire survey, a randomly selected sample of 1500 subjects was invited to a clinical follow-up study. The methods included a structured interview using a modified GA2LEN study questionnaire for registration of symptoms and possible determinants of disease. Spirometry was performed before and after bronchodilation. The age distribution of the sample was 23-72 years. Of 684 subjects attending, 565 completed acceptable spirometric measurements. The prevalence of COPD defined by the GOLD criteria was 7.1%; in men 10.9% and in women 3.9% (p = 0.002). Of those 3.4% had a mild disease, 2.8% a moderate and 0.9% a severe disease. In ages >50 years, 23.5% of men and 6.8% of women had COPD. Among smokers aged >60 years (all men), 47.8% had COPD. None of the women with COPD had been smokers. Increasing age, smoking and male sex were the dominating risk factors, although male sex lost its significance in a multivariate setting. The prevalence of COPD among adults in northern Vietnam was 7.1% and was considerably higher among men than women. The prevalence increased considerably with age. Increasing age and smoking, the latter among men only, were the most important determinants of COPD.

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Section: Discussionsupporting

confidence: 88%

Prevalence of COPD by Disease Severity in Men and Women in Northern Vietnam

Lâm

Ekerljung

Rönmark³

et al. 2014

COPD: Journal of Chronic Obstructive Pulmonary Disease

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“…COPD now affects 8% of adults in the USA7 and more than 10% of adults in Denmark 8 9. In NTM case series worldwide, a high prevalence of comorbid chronic respiratory diseases (particularly COPD but also pneumoconiosis and bronchiectasis) has been observed affecting between 10% and 50% of all patients with NTM 1 5 10–12.…”

Section: Introductionmentioning

confidence: 99%

Chronic respiratory disease, inhaled corticosteroids and risk of non-tuberculous mycobacteriosis

Andréjak

Nielsen

Thomsen

et al. 2012

Thorax

302

211

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Background Chronic respiratory disease and inhaled corticosteroid (ICS) therapy for chronic obstructive pulmonary disease (COPD) increase the risk of pneumonia. Few data are available on the association of these risk factors with non-tuberculous mycobacterial (NTM) pulmonary disease. Methods This study examined chronic respiratory diseases and ICS use as risk factors in a populationbased case-control study encompassing all adults in Denmark with microbiologically confirmed NTM pulmonary disease between 1997 and 2008. The study included 10 matched population controls per case. Conditional logistic regression was used to compute adjusted ORs for NTM pulmonary disease with regard to chronic respiratory disease history. Results Overall, chronic respiratory disease was associated with a 16.5-fold (95% CI 12.2 to 22.2) increased risk of NTM pulmonary disease. The adjusted OR for NTM disease was 15.7 (95% CI 11.4 to 21.5) for COPD, 7.8 (95% CI 5.2 to 11.6) for asthma, 9.8 (95% CI 2.03 to 52.8) for pneumoconiosis, 187.5 (95% CI 24.8 to 1417.4) for bronchiectasis, and 178.3 (95% CI 55.4 to 574.3) for tuberculosis history. ORs were 29.1 (95% CI 13.3 to 63.8) for patients with COPD on current ICS therapy and 7.6 (95% CI 3.4 to 16.8) for patients with COPD who had never received ICS therapy. Among patients with COPD, ORs increased according to ICS dose, from 28.1 for low-dose intake to 47.5 for high-dose intake (more than 800 μg/day). The OR was higher for fluticasone than for budesonide. Conclusion Chronic respiratory disease, particularly COPD treated with ICS therapy, is a strong risk factor for NTM pulmonary disease.

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“…The estimated COPD prevalence among individuals 35 y of age or older in developed countries ranges from 5 to 19%, with the majority being in the vicinity of 10%; in Denmark, it is 17.4%. 1 COPD is an incurable disease. Lifestyle changes, such as smoking cessation and physical exercise, alongside treatments to relieve the symptoms, delay the progress of the disease and improve the individual's ability to stay active as well as prevent exacerbations and treat complications.…”

Section: Introductionmentioning

confidence: 99%

Socioeconomic Variations in Use of Prescription Medicines for COPD: A Register-Based Study

et al. 2016

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BACKGROUND: The purpose of this study was to examine socioeconomic variations in the use of prescription medicines among elderly subjects with COPD. METHODS: Data from the Danish national administrative registers were used. The study population included 1,365 individuals >60 y old residing in the Municipality of Copenhagen and diagnosed with COPD in a hospital setting in 2007. Logistic regression analysis was applied to examine the associations between the use of all prescription medicines for obstructive pulmonary diseases and the use of long-acting bronchodilators, in subject groups of different socioeconomic position. RESULTS: The study demonstrated that approximately 90% of subjects with COPD purchased at least one prescription medicine for obstructive pulmonary diseases, whereas approximately 50% purchased a long-acting bronchodilator. Medicine use did not vary according to educational status or personal wealth. CONCLUSIONS: There were no systematic socioeconomic differences in the use of relevant prescription medicines in elderly subjects diagnosed with COPD in hospital settings in Copenhagen. However, our findings indicate a gap between guideline recommendations and observed use of long-acting bronchodilators and hence suboptimal quality of treatment in the elderly COPD population.

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Prevalence of COPD in Copenhagen

Abstract: The prevalence of COPD in Denmark is among the highest in the world. It is closely correlated to smoking and age. It is accompanied by substantial co-morbidity and it is grossly under treated.

Cited by 53 publications

References 35 publications

Prevalence of COPD by Disease Severity in Men and Women in Northern Vietnam

Prevalence of COPD by Disease Severity in Men and Women in Northern Vietnam

Chronic respiratory disease, inhaled corticosteroids and risk of non-tuberculous mycobacteriosis

Socioeconomic Variations in Use of Prescription Medicines for COPD: A Register-Based Study

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