Prevalence of Congenital Heart Disease in Pediatric Patients with Down Syndrome in Fayoum Governorate

Abstract

Introduction: Congenital heart disease (CHD) is the leading cause of mortality and morbidity during the first two years of the Down Syndrome (DS) patient's life. Studies showed that 40-63.5% of DS patients had CHD. The defects can involve the heart walls, valves, veins, and arteries. They might develop congestive heart failure, pulmonary vascular disease, pneumonia, or failure to thrive. Aim of the study:The current study aimed to define the prevalence and patterns of congenital heart disease (CHD) among children with Down syndrome (DS) in Fayoum Governorate. Subjects and Methods:The study recruited 150 pediatric DS patients from the cardiology and genetic