Prevalence of comorbidities in a surgical pectus excavatum population

Abstract

Background: Pectus excavatum is the most common chest wall deformity and is associated to various connective tissue, cardiopulmonary, and skeletal abnormalities. Several conditions and syndromes have been associated to pectus excavatum, although the overall health implications of the pectus excavatum phenotype are unclear. Therefore, in this study we aimed to examine the health implications of the pectus excavatum phenotype by assessing all comorbidities and previous medical conditions in a cohort of patients undergoing pectus excavatum surgery. Methods: This single-centre retrospective prevalence study included 1,046 patients undergoing minimal invasive repair of pectus excavatum from 2001 to 2012. Hospital medical charts were assessed and comorbidities and previous medical conditions were registered systematically and categorized according to the affected organ system. Results: In our study population of 1,046 patients, we registered 623 conditions. The median age was 17 years and the majority of patients (56%) had no previous or present conditions. Notable prevalence of asthma (8.8%), allergies (12.3%), previous hernia surgery (5.2%), and psychiatric conditions (4.9%) were found. Conclusions: The majority of patients undergoing pectus excavatum surgery have no comorbidities or previous medical conditions. It seems that this patient category is comparable to the background population in this regard and our findings do not support screening this patient category for associated conditions.

Epidural analgesia and abnormal coagulation in patients undergoing minimal invasive repair of pectus excavatum

“…No cases of spinal hematomas have been reported in patients treated with EA undergoing MIRPE. Patients undergoing MIRPE are characterized by (1) the large majority of patients being healthy males,[ 22 ] (2) the prevalences of abnormal INR and PC being very low, (3) no patient receiving anticoagulant medication, 4) as MIRPE is elective surgery, all patients being without concurrent systemic infection, and (5) the MIRPE procedure being associated with a low risk of bleeding. All these factors reduce the risk of serious adverse effects when applying EA to highly theoretical and very low estimates.…”

Embarrassed Radiofrequency Catheter Ablation of Supraventricular Tachycardia in Pectus Excavatum

“…Cardiac arrhythmias are caused by compression of RA and RV against the sternum, left atrium (LA) compression against the spinal column, and lateral displacement of the heart to the left. The observed arrhythmias are supraventricular tachycardia, AF, premature ventricular complex, and VT [1][2][3][4]. AF was documented in two thirds of the patients with mild form pectus excavatum.…”

“…Chest wall deformity such as pectus excavatum is associated with different types of cardiac arrhythmias. Supraventricular and ventricular arrhythmia often occur regardless of chest repair operation (Nuss operation), which is caused by compression of the anterior sternal wall [1][2][3][4]. In addition, repair operation of pectus excavatum can change thoracic cavity dimension and geometry [5].…”

Đánh giá kết quả phẫu thuật Nuss điều trị lõm ngực bẩm sinh

“…Tỷ lệ nam/nữ là 7,4/1, cao hơn nghiên cứu của K. Pawlak (2018) với tỷ lệ nam/nữ là 3,8/1 [5], A. Media (2021) là 6,7/1 [6]. BMI trung bình là 17,5 ± 1,99 kg/m2.…”