“…1 In children ages 2.5 to 15 years this prevalence has been reported as between 0.3% and 1.3%. [2][3][4] Studies have shown an association between CD and numerous autoimmune and rheumatic conditions including rheumatoid arthritis, 5,6 juvenile idiopathic arthritis (JIA), [7][8][9][10] autoimmune thyroiditis, [10][11][12] autoimmune thrombocytopenic purpura, hemolytic anemia, 6 vasculitis, 5,6 polymyositis and dermatomyositis, 13,14 systemic lupus erythematosus (SLE), 5,6,15,16 scleroderma, 5,6 mixed connective tissue disease, 5 diabetes mellitus, [17][18][19][20][21][22] Sjögren syndrome, 6,10,23,24 and dermatitis herpetiformis. 24 Among the connective tissue disorders, only Sjögren syndrome appears to share the HLA DQ2/DQ8 haplotype with CD.…”