Prevalence of cleft lip and palate in Brazilian children 2011 - 2015

Andrade, Natália Medeiros; Fernandes, Tiago Virgínio; Catão, Everton de Sousa; Silva, Gustavo Correia Basto da; Fernandes, Liege Helena Freitas; Cavalcanti, Alidianne Fábia Cabral; Cavalcanti, Alessandro Leite

doi:10.4314/ijmu.v13i1.3

Cited by 3 publications

(8 citation statements)

References 6 publications

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“…In this study, a higher frequency of cases of children with orofacial clefts born with normal weight was identified. This result is consistent with findings of Brazilian (23,24) and Thailand (28) studies which demonstrated that the majority of infants with orofacial clefts had normal birth weight.…”

Section: Discussionsupporting

confidence: 92%

“…Cleft palate alone is more common in women, while cleft palate and lip is more frequent among males, across various ethnic groups (20). In the present study, most children with clefts were males, corroborating similar results found in literature (2,(20)(21)(22)(23). Molecular and genetic studies are needed to better understand the differences between the types of oral clefts and gender (20).…”

Section: Discussionsupporting

confidence: 91%

“…The Brazilian Information System on Live Births is a reliable source of information for the analysis of live births with orofacial clefts (18,23). Therefore, considering the prevalence found and the negative impact that this condition implies on the quality of life of these children and family members (2,29,30), the care provided by the government to those born with orofacial clefts should be made in a comprehensive way through the adoption of public health policies directed to this population group.…”

Section: Discussionmentioning

confidence: 99%

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An ecological study on orofacial clefts in northeastern Brazil

Alessandro¹,

Catão²,

Tiago³

et al. 2019

Acta fac medic Naissensis

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Section: Discussionsupporting

confidence: 92%

Section: Discussionsupporting

confidence: 91%

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

An ecological study on orofacial clefts in northeastern Brazil

Alessandro¹,

Catão²,

Tiago³

et al. 2019

Acta fac medic Naissensis

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“… 19 , 20 For maternal age, there is no consensus in the literature. Although the age group from 20 to 29 years was more predominant in this and other studies, 14 , 15 , 23 the literature also points to a higher occurrence of OC in children whose mothers were of intermediate age, up to 34 years of age, 16 , 22 , 23 and advanced age, from 35 years onwards. 25 Maternal age differences may have occurred due to possible methodological differences in the studies or possible confounding factors in the analyzed populations.…”

Section: Discussionsupporting

confidence: 53%

Epidemiologic profile and prevalence of live births with orofacial cleft in Brazil: a descriptive study

Silva,

Calumby,

Freitas

2024

Rev. paul. pediatr.

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Objective: To describe the epidemiological profile and prevalence of live births with orofacial clefts in Brazil between 1999 and 2020. Methods: Descriptive study. The population corresponded to live births with isolated orofacial clefts in Brazil registered in the Live Birth Information System between 1999 and 2020. Descriptive variables were selected according to their availability and grouped into socioeconomic and demographic, maternal and child health care, and biological variables. Data were submitted to a descriptive analysis using the Software for Statistics and Data Science (STATA). Results: During the period, 33,699 children were born with orofacial clefts, and 82.1% (27,677) of them were isolated clefts. Regarding these cases, the majority were cleft lip and palate (9,619 or 34.7%), followed by cleft palate (9,442 or 34.1%), and by cleft lip (8,616 or 31.3%). Conclusions: Live births with orofacial clefts in Brazil were male, white, with birthweight ≥2,500 g and gestational age ≥37 weeks, born by cesarean section, and with Apgar scores ≥7. The cases were more frequent among mothers who were in their first and single pregnancy and had seven or more prenatal appointments. The mothers were 20 and 29 years old, had eight to ten years of study, and were single. The national prevalence of clefts was 4.24/10,000. The South and Southeast regions of Brazil had the highest prevalence, while the lowest prevalence was recorded in the Northeast and North regions. For the Federative Units, the highest and lowest prevalences were found, respectively, in Paraná and Acre.

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“…25 Also, the prevalence of the disease in Brazil was about 5.2/10 000. 26 Compared with some cities in our country, we found that the prevalence of cleft lip and/ or palate in Guangdong province was lower than that in Beijing (18.9/10 000) 9 and Gansu province (13.48/10 000). 27 The results of our present study revealed the epidemiological characteristics and spatio-temporal trends of cleft lip and/or palate in Guangdong, the most economically developed province in South China.…”

Section: Discussionmentioning

confidence: 48%

Prevalence of cleft lip and/or cleft palate in Guangdong province, China, 2015–2018: a spatio-temporal descriptive analysis

et al. 2021

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ObjectivesThis study aimed to investigate the temporal and spatial characteristics of cleft lip and/or palate based on a large-scale birth defect monitoring database.MethodsData on perinatal infants and children with cleft lip and/or palate defects from 1 January 2015 to 31 December 2018 in Guangdong province of China were collected. The variables including the demographic data, basic family information (address, education level, etc.), the infant’s birth weight, gender and other basic parameters were collected and analysed.ResultsDuring the study period, the prevalence of cleft lip and/or palate was 7.55 per 10 000 perinatal infants. The prevalence of cleft lip, cleft palate and cleft lip and palate were 2.34/10 000, 2.22/10 000 and 2.98/10 000, respectively. The prevalence of cleft lip and/or palate showed a pronounced downward trend, reducing from 8.47/10 000 in 2015 to 6.51/10 000 in 2018. We observed spatial heterogeneity of prevalence of cleft lip and/or palate across the study period in Guangdong. In the Pearl River Delta region, the overall prevalence of cleft lip and/or palate was 7.31/10 000, while the figure (7.86/10 000) was slightly higher in the non-Pearl River Delta region (p<0.05). Concerning infant gender, the prevalence was in general higher in boys than girls (p<0.05). In addition, the higher prevalence was more common in mothers older than 35 years old. For the birth season, infants born in spring tended to have a higher prevalence than those born in other seasons, regardless of the prevalence of cleft lip and palate calculated separately or jointly (p<0.05). The majority of newborns with cleft lip and palate were accompanied by other birth defects.ConclusionThis study contributes a better understanding of the characteristics of spatio-temporal trends for birth defects of cleft lip and/or palate in south China.

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Prevalence of cleft lip and palate in Brazilian children 2011 - 2015

Cited by 3 publications

References 6 publications

An ecological study on orofacial clefts in northeastern Brazil

An ecological study on orofacial clefts in northeastern Brazil

Epidemiologic profile and prevalence of live births with orofacial cleft in Brazil: a descriptive study

Prevalence of cleft lip and/or cleft palate in Guangdong province, China, 2015–2018: a spatio-temporal descriptive analysis

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