Prevalence of Chronic Constipation and Its Associated Factors in Pars Cohort Study: A Study of 9000 Adults in Southern Iran

Moezi, Parinaz; Salehi, Alireza; Molavi, Hossein; Gandomkar, Abdullah; Imanieh, Mohammad Hadi

doi:10.15171/mejdd.2018.94

Cited by 42 publications

(54 citation statements)

References 37 publications

(38 reference statements)

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“…This part of our results is consistent with the evidence obtained from similar studies conducted in Iran [15,34]. These results could be interpreted as opium use affects digestive system function by increasing the duration of digestive tract exposure to food and consumed carcinogens through reducing the movement of food through the system [24,47]. By increasing the amount of fibre intake, the consumption of fruit and vegetables can reduce this effect of opium consumption on the digestive tract [48].…”

Section: Discussionsupporting

confidence: 92%

Opium and risk of gastrointestinal cancer: a case-control study

Vazirinejad¹,

Najafipour²,

Rezaeian³

et al. 2020

Turk J Med Sci

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Background/aim: Gastrointestinal (GI) cancers are among the most common cancers in the world. Many risk factors may increase the chance of developing GI cancers. In recent years, a number of epidemiological studies have reported evidence of carcinogenic effects of opium in humans. This study aimed to investigate the relationship between opium use and GI cancer. Materials and methods: This case-control study was performed on 95 patients with GI cancer and 190 healthy individuals (matched for age, sex, place of residence, and smoking) in Rafsanjan, Iran, in 2018. Diet information, as well as history of smoking, the use of hookah, opium, and its derivatives was collected using a checklist in interview sessions. Conditional logistic regression was performed to investigate the proposed relationship and to estimate odds ratios (OR). Results: After adjusting the confounding variables, the use of opium was significantly associated with an increased risk of GI cancer development (OR = 5.95, 95% CI: 2.4-14.9). Also, a dose-response association was found between the cumulative use of opium and the risk of GI cancers. Consumption of fruit and vegetables reduced the risk of developing GI cancers in opium users (OR = 4.9 and 4.7, respectively). Conclusion: Opium, in the form used among drug users in this area, can lead to an increased risk of GI cancers. Fruit and vegetables have a protective and modifying effect on the risk of GI cancer development caused by opium consumption.

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Section: Discussionsupporting

confidence: 92%

Opium and risk of gastrointestinal cancer: a case-control study

Vazirinejad¹,

Najafipour²,

Rezaeian³

et al. 2020

Turk J Med Sci

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“…The relationship between depression and constipation has been documented in two large population-based studies. In Iran, depression was found to be a significant predictor of chronic constipation [ 25 ]. Another study, using data from the National Health and Nutrition Examination Survey (NHANES) in the United States, found a higher proportion of depressed subjects with chronic constipation than non-depressed subjects [ 26 ].…”

Section: Discussionmentioning

confidence: 99%

Functional Constipation and Anorexia in Community-Dwelling Older Adults: Korean Frailty and Aging Cohort Study (KFACS)

Jeong

Kim

et al. 2021

IJERPH

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Anorexia is a relevant geriatric syndrome because it accounts for most malnutrition in older adults. Constipation has been suggested as a risk factor for anorexia. This study aimed to examine the association between anorexia and functional constipation in community-dwelling older adults. Data on 899 subjects aged 72–86 years were obtained from a follow-up survey of the Korean Frailty and Aging Cohort Study in 2018. Anorexia was assessed using the Simplified Nutritional Appetite Questionnaire (SNAQ), while functional constipation was diagnosed based on Rome IV criteria. Anorexia and functional constipation were present in 30.9% and 19.6% of the participants, respectively. Age, female sex, chewing problems, malnutrition, polypharmacy, low Mini-Mental Status Examination (MMSE) score, depressed mood, low serum albumin, and functional constipation were associated with anorexia in the univariate analysis. In the multivariate logistic regression, functional constipation was associated with anorexia (OR 1.478, 95% CI 1.038–2.104) after adjusting for age, female sex, and MMSE score. However, after further adjusting for depressed mood (OR 2.568) and chewing problems (OR 2.196), the relationship was no longer significant. This study showed that functional constipation is associated with anorexia in community-dwelling older adults, but this association is confounded by depressed mood and chewing problems.

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“…Physical inactivity in this study was not associated with the IC prevalence, and this may have happened because only physical activity was evaluated, not physical exercise. However, physical activity and proper nutrition appear as important actions to regulate gastrointestinal motility, as a high-fiber diet can increase stool weight, resulting in a shorter colon transit time, while a low-fiber diet leads to constipation (27) , while physical activity can increase propulsion movements in the large intestine (28) .…”

Section: Discussionmentioning

confidence: 99%

Prevalence and Factors Associated With Constipation in Premenopausal Women: A Community-Based Study

Dantas

Barbosa

Castro

et al. 2020

Arq. Gastroenterol.

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BACKGROUND: Intestinal constipation is characterized by problems related to evacuation, and presents high prevalence in the female gender. This condition has demonstrated negative effects on the development of daily activities, causing damage to the physical and emotional well-being of individuals who are diagnosed with it. Studies that investigate what health impairments intestinal constipation can cause are scarce in the literature. OBJECTIVE: This study aimed to verify the prevalence and factors associated with intestinal constipation in premenopausal women living in Northeastern Brazil. METHODS: It is a cross-sectional study. This was carried out in the northeast of Brazil. Participated 195 women, adult and middle age. Social conditions, habits and lifestyle, clinical aspects and obstetric history were investigated. Constipation was diagnosed using the Rome III Criteria. Multivariate analysis was conducted using Poisson Regression with robust variance to analyze the relationship between intestinal constipation and independent variables. A statistical significance level of P<0.05 was considered. RESULTS: Most of the women were between 25 and 39 years old (49.2%) and had an income of up to one minimum wage (79.5%). The intestinal constipation prevalence was 35.4%. In the final multivariate regression model, hemorrhoid clinical aspects (P=0.01), pain (P=0.001) and a burning sensation (P=0.01) on bowel movement, and sexual dysfunction (P=0.03) remained associated with constipation. CONCLUSION: The present study found a significant prevalence of constipation among premenopausal women and clinical factors such as hemorrhoids, pain and a burning sensation, and sexual dysfunction were associated with intestinal constipation.

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Prevalence of Chronic Constipation and Its Associated Factors in Pars Cohort Study: A Study of 9000 Adults in Southern Iran

Cited by 42 publications

References 37 publications

Opium and risk of gastrointestinal cancer: a case-control study

Opium and risk of gastrointestinal cancer: a case-control study

Functional Constipation and Anorexia in Community-Dwelling Older Adults: Korean Frailty and Aging Cohort Study (KFACS)

Prevalence and Factors Associated With Constipation in Premenopausal Women: A Community-Based Study

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