Prevalence of Chlamydia trachomatis Antibodies Among Infertile Subjects in Anambra State, Nigeria

Emele, Felix Emele; Anaghalu, I.C.; Adimma, E.D.; Okonkwo, J. E. N.

doi:10.1016/j.ijid.2008.05.443

Cited by 2 publications

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“…21,[24][25][26][27][28] The higher prevalence rates were reported in Palestine (20.2%), Nigeria (28.0%), Netherlands (29.5%), Italy (31.8%), Iran (32.0%), and Tanzania (36.21%). [29][30][31][32][33][34] Studies from New Delhi, India observed also a higher prevalence of CT among infertile women than in current research (28.1% vs 15.6%). 35 The prevalence rate of CT among subfertile women in Vietnam in our study was within the reported range.…”

Section: Discussioncontrasting

confidence: 60%

Prevalence, risk factors and genotyping of chlamydia trachomatis from endocervical specimens of infertile women at a tertiary care hospital, Vietnam

Nguyen,

Do Ngoc,

Nguyen Le

et al. 2024

Int J STD AIDS

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Background To our knowledge, the prevalence, risk factors and distribution of C. trachomatis genotypes are rarely mentioned in Vietnam. This study aimed to find the prevalence, risk factors and distribution of C. trachomatis genotypes in infertile Vietnamese women. Methods Endocervical swabs were collected from infertile women at the National Hospital of Obstetrics and Gynecology, Vietnam, between January 2020 and December 2021. All samples were analyzed for C. trachomatis presence by Cobas 4800 CT/NG Test. Sequencing methods of ompA gene were used to determine the C. trachomatis genotypes. An approximately 1200 bp ompA fragment was aligned with reference sequences from GenBank to identify the corresponding genotype. Results The prevalence of endocervical C. trachomatis infection was 15.6% of 761 participants. Factors independently associated with CT infection among infertile women, obtained by multivariate analysis, included abnormal vaginal discharge, cervicitis, lower abdominal pain, a history of ectopic pregnancy, having more than one sex partner, and age at first intercourse. Among the samples, genotype E (25.93%) was most frequently found, followed by genotypes D/Da (22.23%), F (13.58%), G/Ga (12.35%), J (12.35%), H (6.17%), K (3.70%), B/Ba (2.47%), and I/Ia (1.23%), respectively. Genotype F was related to types of infertility, and genotype H was associated with a history of miscarriage. Conclusions The present study indicated a high prevalence of C. trachomatis in infertile Vietnamese women. The most common genotypes found in this population were E, D, and F. Our findings suggest that routine screening is necessary for early detection and performance of infection control methods.

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Section: Discussioncontrasting

confidence: 60%

Prevalence, risk factors and genotyping of chlamydia trachomatis from endocervical specimens of infertile women at a tertiary care hospital, Vietnam

Nguyen,

Do Ngoc,

Nguyen Le

et al. 2024

Int J STD AIDS

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“…Several reports (12,13) show that adolescent reproductive health is poor in Nigeria -leading to an early referral of young females to fertility clinics. Previous authors reported high coital activity among minors in Nigeria (14) as well as growing infertility due to previous exposures to undetected, untreated, or poorly treated sexually transmitted infections, especially in females (15,16). This raises the need for regular screening of sexually active adolescent females for potential agents of genital tract infections, especially C. trachomatis.…”

Section: Introductionmentioning

confidence: 99%

Vaginal Carriage of Chlamydia Trachomatis and Other Sexually Transmissible Pathogens Among Adolescents in Nigeria

Emele

Agbakoba

Chukwuka

et al. 2019

Gynecol Obstet Reprod Med

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Objectives: Chlamydia trachomatis remains a major cause of genital tract infection and can cause undesirable consequences, such as female infertility. Adolescent girls are physiologically more vulnerable to genital tract infection than older women and need regular screening for genital pathogens. We, therefore, saw the need to screen teenage high school girls in the Anambra State of Nigeria for Chlamydia trachomatis and other potential urogenital pathogens.Study design: This was a Cross sectional study involving 100 randomly selected high school girls, aged 13-18 years, who consented to the study. High vaginal swab samples were collected from the subjects and were analyzed microbiologically; genomic DNA was extracted from each specimen and subjected to PCR analysis. Semi-structured, pre-tested, questionnaires were used to collect relevant bio-data from the participants. The results were analyzed using Chi-square test and percentages.Results: Of the 100 girls, 47(47%) harbored sexually transmissible pathogens in the vagina. Overall, sixty five different kinds of potential urogenital pathogens were recovered, some in co-infection. Organisms represented were as follows: Chlamydia trachomatis, 4(4%); genital Mycoplasmas, 10(10%); Ureaplasmas, 10(10%); Gardnerella vaginalis, 10(10%); and Candida 31(31%). Majority of the girls sought medical treatment from sources other than the hospitals (X2 = 75.9017; p< 0.05).Conclusion: Results showed that sexually transmitted pathogens were common in the high school girls, and alerts of the need for regular vaginal screening and proper medical enlightenment of the adolescents.

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Prevalence of Chlamydia trachomatis Antibodies Among Infertile Subjects in Anambra State, Nigeria

Cited by 2 publications

References 0 publications

Prevalence, risk factors and genotyping of chlamydia trachomatis from endocervical specimens of infertile women at a tertiary care hospital, Vietnam

Prevalence, risk factors and genotyping of chlamydia trachomatis from endocervical specimens of infertile women at a tertiary care hospital, Vietnam

Vaginal Carriage of Chlamydia Trachomatis and Other Sexually Transmissible Pathogens Among Adolescents in Nigeria

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