Background: Turnover intention is a major cause of reduced team morale and low work efficiency. It hinders work performance and reduces the quality of medical services. This study aimed to investigate the relationship between financial satisfaction and turnover intention and its mediators among primary care providers.Methods: Stratified sampling was used to select 1241 participants from three counties in Anhui province, China. Data were collected using self-administered questionnaire. Turnover intention was assessed with a turnover intention assessment scale. Social support and burnout were measured with the 12-item Perceived Social Support Scale and the Chinese version of the Maslach Burnout Inventory, respectively. Structural equation modeling was used for data analysis.Results: The findings showed high turnover intention among primary care providers (mean score 14.16±4.337), and most providers reported low financial satisfaction (mean score 2.49±0.990). The mean social support score was 64.93±13.229, and only 6.1% of primary care providers reported no burnout. Compared with participants with high financial satisfaction, those with low financial satisfaction were more likely to report higher turnover intention (β=−0.216, p<0.001), more social support (β=0.181, p<0.001), and more severe burnout (β=−0.123, p<0.05). Turnover intention may be related to social support (β=−0.147, p<0.001) and burnout (β=0.239, p<0.001). Furthermore, the effect of financial satisfaction on turnover intention was significantly mediated by social support (β=−0.027, p<0.001) and burnout (β=−0.029, p<0.05).Conclusions: Turnover intention is associated with financial satisfaction, with this association mediated by social support and burnout. A reasonable mechanism needs to be established to improve the financial satisfaction and social support and reduce burnout among primary care providers.