Occurrence of Bombay blood group is not uncommon in various parts of Rajasthan. If serum grouping is
not performed and coombs cross matching not done, it is misdiagnosed as blood group O and hospitals
might end up transfusing incompatible blood units to such patients (with O group blood). This study was conducted to determine
the prevalence of Bombay blood group amongst the cross match discrepant O blood group patients. Out of the total 7649 cross
matches performed during one year, we had 63 such discrepant cases for which we had to perform detailed immunohaematology work up to obtain compatible blood unit for the given patients' samples. Routine and advanced
immunohaematology work was done to determine the blood group and to nd the compatible blood unit for transfusion. One
sample was found to be having Bombay blood group which belonged to a 19 year old primigravida Muslim female who had
presented 38 weeks Amenorrhea and abdominal pain. Reverse blood grouping with O cells and coombs cross match must be
adopted by all blood banks. Also, a rare blood type donor le must be maintained in all blood banks.