Prevalence of Beta-Hemolytic Streptococci Groups A, C, and G in Patients with Acute Pharyngitis

Naik, Trupti B.; Nadagir, Shobha D.; Biradar, Asmabegaum

doi:10.4103/0974-2727.176235

Cited by 16 publications

(9 citation statements)

References 13 publications

(14 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The incidence of the asymptomatic carriage of potentially pathogenic β-hs found in healthy young adult subjects is in the range of that reported by other authors [2][3][4][5]. however, in-depth comparative analysis of our results with respect to world literature reveals some significant differences.…”

Section: Discussioncontrasting

confidence: 41%

“…it should be noted, however, that although these values concerned adults (18-92 years), more detailed information on the distribution of different β-hs serogroups in narrower age groups (including those close to the interval analysed in our study) was not available. β-hs were found in 11 out of 88 (13.4%) asymptomatic subjects (control group) in a study on the prevalence of these bacteria in patients with pharyngitis in india [5]. gas and gcs were observed in a similar group of people, i.e.…”

Section: Discussionmentioning

confidence: 95%

See 1 more Smart Citation

The carriage of potentially pathogenic β-haemolytic streptococci (β-HS) in healthy adult inhabitants of Wielkopolska, Poland

Bura¹,

Michalak²,

Padzik³

et al. 2016

fmpcr

View full text Add to dashboard Cite

Background. acute pharyngitis is a common disease in primary health care patients. Beta-hemolytic streptococci (β-hs) are a frequent etiological agent, while swab culture from the throat and palatine tonsils is the gold standard for diagnosis. Objectives. The evaluation of the prevalence of potentially pathogenic β-hs carriage in young adult inhabitants of wielkopolska, Poland. Material and methods. The study included 205 healthy young adult (18-44 years old) (29.0 ± 6.4) inhabitants (M -95, F -110) of wielkopolska, Poland. Two swabs were taken from the throat: the first one was used to perform a rapid antigenic diagnostic test (radT) for group a streptococci (gas) and the second to grow a conventional culture. if β-hs grew, isolates were serotyped according to lancefield. in addition, simple demographic and medical data were collected from the subjects. The study was financed from funds granted within the first edition of the "give a hand" project (karol Marcinkowski Poznan University of Medical sciences). Results. Positive throat cultures were obtained in 15.6% out of 205 persons (n = 32). The distribution of β-hs serogroup results was as follows: group c (gcs) -17 cases (53.1% of cases where β-hs growth was positive), group F (gFs) -9 cases (28.1%), gas -3 people (9.4%) and group g (ggs) -3 subjects (9.4%). The growth of the discussed bacteria in cultures was moderate or high in 53% of these cases. radT was positive in 5 cases (but only one person had gas in throat culture). The positive culture result was significantly more frequent in men (62.5% out of 32 cases with β-hs growth, p = 0.0460). Conclusions. 1. The possibility of β-hs carriage must be taken into account when analysing the results of throat swab cultures. 2. gas carriage is significantly lower than non-gas carriage. 3. gcs were the most prevalent among non-gas. 4. Being male may predispose individuals to β-hs carriage. Key words: culture, streptococci, carriage, lancefield, radT, pharyngitis.

show abstract

Section: Discussioncontrasting

confidence: 41%

Section: Discussionmentioning

confidence: 95%

The carriage of potentially pathogenic β-haemolytic streptococci (β-HS) in healthy adult inhabitants of Wielkopolska, Poland

Bura¹,

Michalak²,

Padzik³

et al. 2016

fmpcr

View full text Add to dashboard Cite

show abstract

“…S.pyogeneshas remained a significant human pathogen for centuries, it causes a wide variety of infections in humans, which vary from mild upper respiratory and skin infections to non-suppurativesequelae like Acute Rheumatic Fever and Rheumatic Heart Disease (8) .The majority of patients were range (2-63 years) these results are similar to a study reported by (9), and also similar to another study reported by (10) .The Samples were from (97) females (45%) and (118) males (55%), the males were predominant more than female, these results are agreement with results of study conducted by (11)(12)(13) and disagree with studies showed by (14,15) , as shown in these result there is no big difference in the sex of patients.The results of the present study displayed that the occurrence of S.pyogenes was 25/290 isolates (6.8%), and this result disagree with a study in Thi-qar revealed by (16) who documented a high emergence of isolates from patients with tonsillitis, but similar to a study revealed by (17) .Nosocomial transmission of GAS infection into patients in the hospital environment has been described in the medical literature, the range of transmission has been limited to small numbers of health care workers (18) .The current study revealed that is no presence of Streptococcus spp. especially S.pyogenes and this result disagree with a study reported by (19) who showed that the rate of Streptococcus species is (2.75) and a high rate of Staphylococcus aureus (41.28).The results appeared 25 of the isolates were positive for 16S rRNA and 24 were positive for emmgene, these results are similar to a study reported by (6) , who showed a similar DNA sequences of the 16S rRNA gene region of GAS isolates.…”

Section: Discussionsupporting

confidence: 87%

Isolation and Identification of Streptococcus pyogenes from Patients and Objects in Hospital Environment in Thi-Qarcity in Iraq

AdyanNafee Abbas,

Qasim Hassan Wida

2021

Indian Journal of Forensic Medicine & Toxicology

View full text Add to dashboard Cite

This study aimed to screen Streptococcus pyogenes in the hospital and investigate the incidence of this bacteria. The genotypes of the S.pyogenes in the study samples will be determined using 16Sr RNA and some virulence factors(emm, scpA, speA genes).The majority of the samples (74.1%) were isolated from patients at the emergency room and (25.9%) were from hospital environment (objects).The current study showed that the total of 215 patients with pharyngitis were included 118 (55%) males higher than 97 (45%) females. The patients' ages ranged from 2 to 62 years, which were divided into four categories. The majority of patients 65 (30.1%) of patients from 3 to 6 years old, 54 (25%) of patients less than 3years, 51 (23.6%) from 7 to 11 years old, and 46 (21.3%) more than 12years. Six isolates sent for sequencing were after that submission in NCBI-GenBank database. The results of nucleotide sequence alignment of the isolates revealed that there are multiple point mutations, four of them appeared as a single nucleotide polymorphism (SNP) and two appeared in duplicate. Polymorphic sites (Mutations) of 6 S.pyogenes isolates.

show abstract

“…There is some doubt about whether they are truly pathogenic or require antibiotic treatment. [97][98][99] Some of these infections have on rare occasions been associated with suppurative complications, e.g. peritonsillar abscess (quinsy), requiring specialist care (such as surgical drainage) and antibiotic treatment.…”

Section: Discussionmentioning

confidence: 99%

Worldwide comparison of treatment guidelines for sore throat

Coutinho

Duerden

Sessa³

et al. 2021

Int. J. Clin. Pract.

View full text Add to dashboard Cite

Introduction Sore throat (acute pharyngitis) is globally one of the most frequent reasons for seeking healthcare. Its etiology is mostly viral. In 15%‐30% of cases, group A streptococci (GAS) are detected, which may cause acute rheumatic fever. We have done a worldwide systematic review to compare diagnostic and therapeutic guidelines across countries and regions. Previous reviews of sore throat guidelines were limited to specific regions and/or language; this is the first global review. Materials and Methods Searches were performed in MEDLINE, EMBASE and COCHRANE (key words: sore throat, pharyngitis, tonsillitis or pharyngotonsillitis, and management, guidance, guideline or recommendation) and on the web sites of major health authorities and associated institutions from Africa, Asia, Europe, Middle East, North America, Oceania and South America. Results Thirty‐six guidelines were identified from 26 countries. Most common are recommendations relying on the symptom‐ and age‐based Centor or McIsaac scores. However, antibiotic treatment may be based on other symptomatic criteria; in the most extreme approach just sore throat in children. The recommendation of GAS‐specific diagnostic tests is mainly limited to countries where such tests are readily available, although some countries choose not to use them. Penicillins are consistently recommended as first‐line antibiotics. By contrast, guidance for symptomatic treatment is variable and mostly sparse or missing. African countries without sore throat guidelines and Asian countries bypassing them are afflicted by rising antibiotic resistance. Conclusion The availability of sore throat guidelines varies considerably by region and country. Moreover, important divergence is found among the guidelines regarding diagnostic and treatment criteria. This may be explained by the historical background or adoption of external guidelines, rather than local incidences of GAS infections or acute rheumatic fever. Absence of recommendations on symptomatic treatment in many guidelines is concerning, and raises issues about antimicrobial stewardship, as this should be the mainstay of sore throat management, rather than antibiotics.

show abstract

Prevalence of Beta-Hemolytic Streptococci Groups A, C, and G in Patients with Acute Pharyngitis

Cited by 16 publications

References 13 publications

The carriage of potentially pathogenic β-haemolytic streptococci (β-HS) in healthy adult inhabitants of Wielkopolska, Poland

The carriage of potentially pathogenic β-haemolytic streptococci (β-HS) in healthy adult inhabitants of Wielkopolska, Poland

Isolation and Identification of Streptococcus pyogenes from Patients and Objects in Hospital Environment in Thi-Qarcity in Iraq

Worldwide comparison of treatment guidelines for sore throat

Contact Info

Product

Resources

About