Prevalence of Behçet's disease in Istanbul, Turkey

Azizlerli, Gülsevim; Köse, Afet Akdağ; Sarıca, Rıfkıye; Gül, Ahmet; Tutkun, İlknur Tuğal; Kulaç, Mustafa; Tunç, Recep; Urgancioğlu, Meri; Dişçi, Rian

doi:10.1046/j.1365-4362.2003.01893.x

Cited by 325 publications

(179 citation statements)

References 6 publications

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“…It is believed to be strongly related to a genetic predisposition, depending on its frequency in a specific geographical area, its close relationship with HLA-B51 in different ethnic groups, and familial distribution. HLA-B51gene positivity is frequently seen in areas where Turkish tribes immigrated along the Silk Road, which seems to support the genetic influence (Azizlerli et al, 2003, Papoutsis et al, 2006Varol et al, 2010;Hamzaoui et al, 2012 …”

Section: Discussionmentioning

confidence: 83%

HLA-B51 subtypes in Turkish patients with Behçet's disease and their correlation with clinical manifestations

Dd¹,

Gg²,

Akoğlu³

et al. 2014

Genet. Mol. Res.

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Section: Discussionmentioning

confidence: 83%

HLA-B51 subtypes in Turkish patients with Behçet's disease and their correlation with clinical manifestations

Dd¹,

Gg²,

Akoğlu³

et al. 2014

Genet. Mol. Res.

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“…as being in the range of 110 -420 per 100,000 and the frequency of HLA-B51 is 24% (25)(26)(27)(28). Portugal, Italy, and Spain are 3 southern European countries with a similar frequency of HLA-B51 in the general population; however, the prevalence of the disease is different, being 5 times higher in Spain than in Portugal.…”

Section: Seventeen-year Study Of Behçet's Disease In Italymentioning

confidence: 99%

Epidemiology and clinical course of Behçet's disease in the Reggio Emilia area of Northern Italy: A seventeen‐year population‐based study

Salvarani¹,

Pipitone²,

Catanoso³

et al. 2007

Arthritis & Rheumatism

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Objective. To investigate the epidemiology and clinical course of Behçet's disease (BD) over a 17-year period in a defined area of northern Italy. Methods. All patients with incident BD diagnosed over a 17-year period (from January 1, 1988 to December 31, 2004) living in the Reggio Emilia area were identified through the following sources: physicians at Reggio Emilia Hospital, medical practitioners, and community-based specialists. We identified all patients registered in a centralized index and in the Reggio Emilia district database for rare diseases. Patients were followed up from the time of diagnosis until either their death or April 1, 2005. Results. Eighteen patients (9 men and 9 women) had complete BD. Mean ؎ SD age at diagnosis was 33 ؎ 7 years. The incidence rate of BD was 0.24 per 100,000. The prevalence of BD on January 1, 2005 was 3.8 per 100,000. No patients died during the followup period. Although all patients developed oral ulceration during the disease course, 22.2% had no oral lesions at disease onset. Eye disease occurred in 55.6%. Ocular disease was more common in men and appeared at disease onset or within the first few years of disease onset (median 3 years). Only 1 patient had loss of useful vision in at least 1 eye at the end of followup. In all affected patients, visual acuity improved once treatment was started. Conclusion. This population-based study is the first to report the prevalence and incidence of BD in Italy. In Italian patients, BD is nonfatal and the prognosis of eye disease is good.

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“…Ülkemizde farklı bölgelerde yapılan epidemiyolojik çalışmalarda Behçet hastalığının görülme sıklığının 80-420/100.000 arasında olduğu kaydedilmiştir (10)(11)(12)(13)(14). Dünyada yapılan çalışmalarla kıyaslandığında bu hastalığın Türkiye'de görülme oranının Asya'ya göre 20-30 kez, Avrupa ve Amerika'ya göre ise yaklaşık 150 kez daha fazla olduğu göze çarpmaktadır (15 (18,19).…”

Section: Introductionunclassified

Investigations of genetic polymorphisms related to Behcet\s disease in Turkish population

Oğuz¹,

Demiryürek²,

Alaşehirli³

et al. 2014

Gaziantep Med J

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It is known that genetic variations are associated with some diseases and increase developing of some diseases while decrease some of them. The recent studies show that genetic polymorphisms have a role on susceptibility and prognosis of Behçet's disease (BD). Knowing the polymorphisms associated with BD and the side of these associations will be useful for explaining the pathogenesis of the disease and to develop more effective therapies. In this review we aimed to overview the recent studies investigated the polimorphisms which may have a role in BD in Turkish population.

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Prevalence of Behçet's disease in Istanbul, Turkey

Cited by 325 publications

References 6 publications

HLA-B51 subtypes in Turkish patients with Behçet's disease and their correlation with clinical manifestations

HLA-B51 subtypes in Turkish patients with Behçet's disease and their correlation with clinical manifestations

Epidemiology and clinical course of Behçet's disease in the Reggio Emilia area of Northern Italy: A seventeen‐year population‐based study

Investigations of genetic polymorphisms related to Behcet\s disease in Turkish population

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