Prevalence of Asymmetry of Mamillary Body and Fornix Size on MR Imaging

Abstract

BACKGROUND AND PURPOSE:Mamillary body and fornix asymmetry are frequent findings on MR imaging of the brain. We sought to determine the prevalence of asymmetry of the fornix and mamillary body on MR imaging in patients with or without seizures.

Mesial Temporal Sclerosis: Accuracy of NeuroQuant versus Neuroradiologist

“…The following findings may also suggest MTS: 1) hippocampal T2-weighted/FLAIR signalintensity abnormalities, 2) loss of the crenated margin of the upper surface of the hippocampus, 3) gray matter-white matter blurring, 4) malrotation of the hippocampus, 5) ipsilateral mammillary body and fornical column volume loss, and 6) unilateral temporal horn dilation (sometimes as secondary findings of volume loss in the limbic system). [21][22][23] The ability to detect changes suggestive of MTS has been shown to be significantly correlated with the experience of the reader and the quality of the study. For example, Von Oertzen et al 24 have shown that the sensitivity for detection of MTS varies between 39% and 50% when comparing nonexpert and dedicated epilepsy expert readers of standard brain MRI, respectively.…”

The Frequency and Extent of Mammillary Body Atrophy Associated with Surgical Removal of a Colloid Cyst

“…Although the present study used a 1.0-mm-volume scan for comparison purposes, previous MR imaging studies of the mammillary bodies have used a variety of section thicknesses (1.0 mm, 31 1.1 mm, 28 1.5 mm, 29,30,32, and 3.0 mm 26,27 ). Other differences included the use of a 3T imaging system because previous MR imagingϪbased measurements of mammillary body volume have used 1.5T systems.…”

“…[27][28][29][30][31][32] An additional MR imaging sequence was used to acquire intracranial volume data for normalizing the data for differences in head size across patients and controls. This sequence was a T2-weighted intracranial volume scan; parameters were TR, 3000 ms; TE, 102 ms; FA, 150°; 3-mm section thickness; 10-mm section gap; acquisition time, 2 minutes.…”

“…This was a challenge because the mammillary bodies are positioned at the base of the brain and are small, with an estimated volume of approximately 50 mm. 3,26,27 Unlike previous MR imaging studies of the mammillary bodies, 28,29 the volume estimates were based on stereology, which uses a randomly generated start section and randomly generated grids for the measurement procedure, therefore ensuring that the volume estimates were unbiased, (ie, sections and grids were not chosen by the observer) and ensuring predictable precision.…”

Mammillary Body

“…7 Although asymmetry of the mammillary bodies and fornices is highly associated with MTS, this could also be seen as a normal variation or congenital abnormality. 8 In this study, we present epileptic focus in mammillary body with refractory epilepsy on 18 F-FDG PET/CT, which is a very unusual site for seizure.…”