Prevalence of asthma in adults in Busselton, Western Australia.

Peat, J. K.; Haby, MM; Spijker, J.; Berry, Geoffrey; Woolcock, Ann J.

doi:10.1136/bmj.305.6865.1326

Cited by 160 publications

(78 citation statements)

References 21 publications

(2 reference statements)

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“…The rates of symptoms in adults were similar to those found in a study of adults in Busselton, Western Australia using an identical protocol [10]. Because few of the adults studied were older than 50 yrs, misclassification due to the presence of chronic airflow limitation was unlikely.…”

Section: Discussionsupporting

confidence: 65%

“…The prevalence of recent wheeze (in the last 12 months) in Australian children doubled from approximately 12% in 1982 to 24% in 1992, and the prevalence of airway hyperresponsiveness (AHR) also doubled in this period but only in atopic children [9]. However, a similar comparison of adults in 1981 and 1990 showed that the prevalence of recent wheeze increased only in subjects less than 30 yrs of age and that the prevalence of AHR had not increased at all, even in atopic subjects [10].…”

mentioning

confidence: 94%

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Differences in airway responsiveness between children and adults living in the same environment: an epidemiological study in two regions of New South Wales

Peat¹,

Gray²,

Mellis³

et al. 1994

Eur Respir J

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D Di if ff fe er re en nc ce es s i in n a ai ir rw wa ay y r re es sp po on ns si iv ve en ne es ss s b be et tw we ee en n c ch hi il ld dr re en n a an nd d a ad du ul lt ts s l li iv vi in ng g i in n t th he e s sa am me e e en nv vi ir ro on nm me en nt t: : a an n e ep pi id de em mi io ol lo og gi ic ca al l s st tu ud dy y i in n t tw wo o r re eg gi io on ns s o of f N Ne ew w S So ou ut th h W Wa al le es s In winter 1991 and 1992, we studied two large random samples of children living in two different regions; and, three months later, we conducted a study of adults who lived with enrolled children. A total of 805 children and 814 adults attended in Lismore, and 850 children and 711 adults in Wagga Wagga. Questionnaires were used to measure symptom history, histamine inhalation challenge to measure airway hyperresponsiveness (AHR) and skin-prick tests to measure allergy.There was a higher prevalence of asthma in children than in adults: recent wheeze was 1.5 times higher; asthma medication use was 1.5 times higher; diagnosed asthma was 1.6 times higher; and AHR was two times higher. Current asthma (AHR and recent wheeze) was 9.5-11.3% in children and 5.4-5.6% in adults. These differences were statistically significant. In both regions, airway responsiveness was more severe in children who were sensitized to common allergens than in similarly sensitized adults.These results suggests that airways can develop protective mechanisms with age, or that recent environmental changes in factors such as allergen levels, diet or treatment practices have led to immunological changes and to incresed airway responsiveness in this generation of children.

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Section: Discussionsupporting

confidence: 65%

mentioning

confidence: 94%

Differences in airway responsiveness between children and adults living in the same environment: an epidemiological study in two regions of New South Wales

Peat¹,

Gray²,

Mellis³

et al. 1994

Eur Respir J

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“…In this study conducted among 955 school children from two schools in Thrissur the prevalence of asthma was found to be 10.4%.This is lower than other studies 9 and higher than most of Indian studies like study by Amir et al 10 , Prasad et al 11 etc. Prevalence of adult asthma in the study done in Kerala was 5.4%.Asthma prevalence among school children in the other studies were 8.4-10.3%.…”

Section: Discussioncontrasting

confidence: 48%

Prevalence of Asthma among School Children Belonging to High and Low Socio Economic Status

Anjana¹

2017

JMSCR

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“…It is the most common chronic disease of childhood and an important cause of absence from school and reduced participation in sports and other activities [2]. Several studies, for example in UK and Australia, have revealed a substantial increase in the prevalence of the disease among children over the last 3 decades [3][4][5][6][7][8]. While some of this maybe due to changes in diagnostic practice, there is general agreement that the increase in the prevalence of symptoms is a true phenomenon [9][10][11].…”

Section: Introductionmentioning

confidence: 99%

Serum Polycyclic Aromatic Hydrocarbons Among Children with and without Asthma: Correlation to Environmental and Dietary Factors

Al-Daghri

2008

International Journal of Occupational Medicine and Environmental Health

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Background: Children from low-income families may be subject to high exposures to polycyclic aromatic hydrocarbons (PAH) which can lead to respiratory disorders. This study aims to establish methods for assessing total PAH exposure of asthmatic and non-asthmatic children from low-income families; to estimate serum PAH concentrations of these children, and to estimate the relative importance of the environmental pathways for PAH exposure. Materials and Methods: A total of 75 (61 asthmatic, 14 non-asthmatic) Saudi children 15 years old and below were included to participate in this crosssectional study. Each participant answered a generalized questionnaire with dietary questions. Serum PAH were measured using HPLC with UV detection. Results: Serum naphthalene and pyrene were significantly elevated among asthmatic children (p-values = 0.007 and 0.01, respectively). Serum acenaphthylene, fluorine and 1,2-benzanthracene, on the other hand, were significantly higher among non-asthmatics (p-values = 0.001, 0.04 and 0.03, respectively). There was a significant correlation between the presence of a smoker in the family and serum concentrations of carbazole, pyrene, 1,2-benzanthracene and benzacephenanthrylene (R = 0.37, 0.45, 0.43, 0.33; p-values = 0.01, 0.0002, 0.003 and 0.025, respectively). Significant correlations were elicited between daily meat intake and serum levels of acenaphthylene, benzopyrene and 1,2-benzanthracene (R = 0.27, 0.27, 0.33; p-values = 0.02 and < 0.001, respectively). Conclusion: Among the children, serum PAH were significantly correlated to meat intake as well as presence of smokers at home. Public health awareness should be enhanced by educating parents to take certain precautions at home, such as preventing indoor smoking and reducing the intake of grilled and smoked meat by children so as to decrease their exposure to carcinogenic PAH.

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Prevalence of asthma in adults in Busselton, Western Australia.

Cited by 160 publications

References 21 publications

Differences in airway responsiveness between children and adults living in the same environment: an epidemiological study in two regions of New South Wales

Differences in airway responsiveness between children and adults living in the same environment: an epidemiological study in two regions of New South Wales

Prevalence of Asthma among School Children Belonging to High and Low Socio Economic Status

Serum Polycyclic Aromatic Hydrocarbons Among Children with and without Asthma: Correlation to Environmental and Dietary Factors

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