Prevalence of asthma and its association with rhinitis in the elderly

Pité, Helena; Pereira, Ana Margarida; Morais‐Almeida, Mário; Nunes, Carlos Pereira; Bousquet, Jean; Fonseca, João

doi:10.1016/j.rmed.2014.05.002

Cited by 35 publications

(32 citation statements)

References 42 publications

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“…[25][26][27][28] Moreover, asthma subjects with rhinitis reported considerably more respiratory symptoms. Besides, considering the ARIA rhinitis classification, the association of rhinitis and current asthma is stronger with regard to the persistency and severity of rhinitis symptoms.…”

Section: Comparison With Others Studiesmentioning

confidence: 99%

“…These findings, supporting an extensive nose lung interaction, are well in agreement with many studies. [25][26][27][28] Moreover, asthma subjects with rhinitis reported considerably more respiratory symptoms. Our results are in line with the study of Erikson et al which found that asthma subjects with comorbid allergic rhinitis had a higher prevalence of symptoms common in asthma.…”

Section: Comparison With Others Studiesmentioning

confidence: 99%

See 1 more Smart Citation

Prevalence of asthma and rhinitis in a Tunisian population

Toujani

Mjid

Ouahchi

et al. 2016

Clinical Respiratory J

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Section: Comparison With Others Studiesmentioning

confidence: 99%

Section: Comparison With Others Studiesmentioning

confidence: 99%

Prevalence of asthma and rhinitis in a Tunisian population

Toujani

Mjid

Ouahchi

et al. 2016

Clinical Respiratory J

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“…The age cutoff for the diagnosis of very late-onset asthma is not consistent but defined as > 50 years in some studies [75] and > 65 years in others [76]. The aging lung is associated with decreased lung function due to loss of elastic recoil and mechanical disadvantages.…”

Section: Introductionmentioning

confidence: 99%

Understanding Asthma Phenotypes, Endotypes, and Mechanisms of Disease

Kuruvilla

Lee

2018

Clinic Rev Allerg Immunol

717

600

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The model of asthma as a single entity has now been replaced by a much more complex biological network of distinct and interrelating inflammatory pathways. The term asthma is now considered an umbrella diagnosis for several diseases with distinct mechanistic pathways (endotypes) and variable clinical presentations (phenotypes). The precise definition of these endotypes is central to asthma management due to inherent therapeutic and prognostic implications. This review presents the molecular mechanisms behind the heterogeneity of airway inflammation in asthmatic patients. Asthma endotypes may be broadly regarded as type 2 (T2) high or T2-low. Several biologic agents have been approved for T2-high asthma, with numerous other therapeutics that are incipient and similarly targeted at specific molecular mechanisms. Collectively, these advances have shifted existing paradigms in the approach to asthma to tailor novel therapies.

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“…This study showed that in aged people, asthma is a common disease and it has a strong association with rhinitis. According to ARIA classification, an especially high odds ratio for asthma is observed in persistent and severe types of allergic rhinitis [47]. …”

Section: Airwaysmentioning

confidence: 99%

“…Frequently in old people asthma remains underdiagnosed (about 8% of diagnosis according to an epidemiological study in Portugal), and the percentage increases when respiratory symptoms are present [47]. Scarcely controlled asthma reduces the functional condition of older people, leads to a loss of independence, and to social withdrawal delaying the call for help and medical attention.…”

Section: Airwaysmentioning

confidence: 99%

Allergy and Aging: An Old/New Emerging Health Issue

Martinis¹,

Sirufo²,

Ginaldi³

2017

Aging and disease

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Allergy reactions are the most common immunological diseases and represent one of the most widespread and fast growing chronic human health problems among people over 15 years of age in developed countries. As populations get older worldwide, allergy manifestations in aged persons will occur more often in the future. To date, there has been much more studies on allergies in children than in adults. As the population ages, clinicians must be prepared to meet all the elderly's health care needs, including these new and emerging health issue. Allergic diseases represent an old/new emerging health issue. Because many common illnesses masquerade as atopic disease, the differential diagnosis of suspected allergic diseases becomes more expanded in an aging population. Research in the field needs to focus on both human and animal model systems to investigate the impact of the aging process on the immunologic pathways underpinning allergy and its different facets.

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Prevalence of asthma and its association with rhinitis in the elderly

Abstract: Asthma is common in the elderly and strongly associated with rhinitis. The OR for asthma is especially high in persistent and severe ARIA classification rhinitis types. This study strengthens the need for an integrated assessment of asthma together with rhinitis in the elderly.

Cited by 35 publications

References 42 publications

Prevalence of asthma and rhinitis in a Tunisian population

Prevalence of asthma and rhinitis in a Tunisian population

Understanding Asthma Phenotypes, Endotypes, and Mechanisms of Disease

Allergy and Aging: An Old/New Emerging Health Issue

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