Prevalence of asthma among Chinese adolescents living in Canada and in China

Wang, Hongyu; Wong, Gary; Chen, Yuzhi; Ferguson, Alexander C.; Greene, Justina M.; Ma, Yu; Zhong, Nanshan; Lai, Christopher; Sears, Malcolm R.

doi:10.1503/cmaj.071797

Cited by 54 publications

(46 citation statements)

References 43 publications

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“…The observed reduced odds of tree nut allergy in immigrants might be due to genetic differences as well as environmental influences. It was reported that the risk for both asthma and eczema increase with the length of stay of immigrant children in North America [38,39] . Indeed, although immigrants had lower odds for tree nut allergy, the odds for shellfish allergy was increased in children who had recently immigrated versus adult immigrants.…”

Section: Discussionmentioning

confidence: 99%

Eczema in Early Childhood, Sociodemographic Factors and Lifestyle Habits Are Associated with Food Allergy: A Nested Case-Control Study

Ben‐Shoshan¹,

Soller

Harrington

et al. 2015

Int Arch Allergy Immunol

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tion between atopy, sociodemographic characteristics and lifestyle habits with probable food allergy. Results: Between September 2010 and September 2011, 480 cases and 4,950 controls completed the questionnaire. For all 9 allergens, factors associated with a higher risk of probable allergy were as follows: (1) personal history of eczema (in the first 2 years of life), asthma or hay fever (odds ratio, OR 2.3, 95% CI 1.6-3.5; OR 2.8, 95% CI 2.2-3.6, and OR 2.3, 95% CI 1.8-3.0, respectively), (2) maternal, paternal or sibling's food allergy (OR 3.7, 95% CI 2.5-5.6; OR 3.0, 95% CI 1.8-5.1, and OR 3.1, 95% CI 2.2-4.2), (3) high household income (top 20%; OR 1.5, 95% CI 1.2-2.0). Males and older individuals were less likely to have food allergy (OR 0.7, 95% CI 0.6-0.9, and OR 0.99, 95% CI 0.99-1.00). Eczema in the first 2 years of life was the strongest risk factor for egg, peanut, tree nut and fish allergy. Conclusions: This is the largest population-based nested casecontrol study exploring factors associated with food allergies. Our results reveal that, in addition to previously reported factors, eczema in the first 2 years of life is consistently associated with food allergies. © 2015 S. Karger AG, Basel Key WordsFood allergy · Eczema · Demographic factors · Lifestyle Abstract Background: Studies suggest an increase in food allergy prevalence over the last decade, but the contributing factors remain unknown. The aim of this study was to evaluate the association between the most common food allergies and atopic history, sociodemographic characteristics and lifestyle habits. Methods: We conducted a case-control study nested within the SPAACE study (Surveying Prevalence of Food Allergy in All Canadian Environments) -a cross-Canada, random telephone survey. Cases consisted of individuals with probable food allergy (self-report of convincing symptoms and/or physician diagnosis) to milk, egg, peanut, tree nut, shellfish, fish, wheat, soy, or sesame. Controls consisted of nonallergic individuals, matched for age. Cases and controls were queried on personal and family history of atopy, sociodemographic characteristics and lifestyle habits. Multivariate logistic regression was used to evaluate the associa-

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Section: Discussionmentioning

confidence: 99%

Eczema in Early Childhood, Sociodemographic Factors and Lifestyle Habits Are Associated with Food Allergy: A Nested Case-Control Study

Ben‐Shoshan¹,

Soller

Harrington

et al. 2015

Int Arch Allergy Immunol

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“…A recent analysis of data from the International Study of Asthma and Allergies in Childhood, comparing data from Vancouver, Canada, with data from centres in China, showed significant differences in prevalence rates between children of similar genetic ancestry living in different environments, with evidence for an effect of duration of residence in the new environment. 9 Prevalence rates for asthma among children 13-14 years old were lowest for Chinese children born and studied in China, intermediate for Chinese children who had migrated during their lifetime to Canada and highest for Chinese children who had been born in Canada. In addition, the prevalence rate for the third of these groups was still lower than among non-Chinese children in the same environment.…”

Section: Epidemiology Of Asthma: An Overviewmentioning

confidence: 97%

Asthma: epidemiology, etiology and risk factors

Subbarao¹,

Mandhane²,

Sears³

2009

Canadian Medical Association Journal

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421

303

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“…The International Study of Asthma and Allergies in Childhood (ISAAC) found that the prevalence of all asthma-related symptoms in adolescents, such as current wheezing, ever wheezing, ever asthma, and wheezing attacks, was highest in Canadian born non-Chinese adolescents, followed by Chinese immigrants living in Vancouver, and was lowest in native Chinese adolescents living in mainland China and Hong Kong [3]. The National Health Interview Survey conducted between 1997 and 2011 also found that adults born outside the USA had lower odds of ever asthma (adjusted OR 0.52, 95% CI 0.49–0.55) or current asthma (adjusted OR 0.50, 95% CI 0.46–0.54) than US-born adults [4].…”

Section: First-generation International Immigrantsmentioning

confidence: 99%

“…The prevalence of asthma in Chinese adolescent immigrants residing in Canada for less than 7 years was 7.7%, compared to 11.2% for those who had lived in Canada for more than 7 years and 15.9% in those who had been born in Canada ( p = 0.006 for trend) [3]. Australian immigrant teenagers aged 13–19 years had a lower prevalence of self-reported wheeze (8.5%) compared to those born in Australia (19.2%).…”

Section: First-generation International Immigrantsmentioning

confidence: 99%

Effects of Migration on Allergic Diseases

Tham

Zhu

2018

Int Arch Allergy Immunol

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Studies in migrant populations provide vital opportunities to investigate the role of environmental factors in the pathogenesis of allergic disorders. Differences in allergy prevalence have been observed between migrants and native-born subjects living in the same geographical location. Immigrants who migrate from less affluent countries with lower allergy prevalence tend to have a lower prevalence of allergic disorders compared to native-born residents of the more affluent host country. The patterns of allergic disease prevalence also differ between first- and second-generation migrants. The timing of migration in relation to birth, age at migration, and duration of residence in the host country also influence one’s atopic risk. A complex interplay of multiple environmental, socioeconomic, and cultural factors is likely responsible for these observed differences. Further research into the roles of various risk factors in modulating differences in allergic disease prevalence between migrant and native populations will enhance our understanding of the complex gene-environment interactions involved in the pathogenesis of allergic disorders.

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Prevalence of asthma among Chinese adolescents living in Canada and in China

Cited by 54 publications

References 43 publications

Eczema in Early Childhood, Sociodemographic Factors and Lifestyle Habits Are Associated with Food Allergy: A Nested Case-Control Study

Eczema in Early Childhood, Sociodemographic Factors and Lifestyle Habits Are Associated with Food Allergy: A Nested Case-Control Study

Asthma: epidemiology, etiology and risk factors

Effects of Migration on Allergic Diseases

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