2019
DOI: 10.1016/j.aller.2018.12.002
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Prevalence of asthma, allergic rhinitis and eczema in 6–7-year-old schoolchildren from Luanda, Angola

Abstract: Background: Epidemiological data have shown that the prevalence of asthma, rhinoconjunctivitis and eczema in children is still increasing, namely in Africa. However, there are no epidemiological studies on asthma or allergic diseases in Angolan children. Objective: To study the prevalence of asthma and other allergic diseases in Angolan children. Methods: Descriptive, observational, cross-sectional study, using the ISAAC study methodology, in the province of Luanda, Angola in 6-7-yearold children. Forty-six (8… Show more

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Cited by 21 publications
(16 citation statements)
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“…These results agree with what has been published in a recent study carried out in children in Angola, where the ISAAC study was used as a reference and reported that asthma symptoms were significantly associated with paracetamol use (OR 3.94; 95% CI 2.29 to 6.81 p<0.001), antibiotic uptake in the first year of life (OR 2.54; 95% CI 1.97 to 3.29 p<0.001), allergic rhinitis symptoms (OR 8.74; 95% CI 7.06 to 10.82 p<0.001) and itchy rash in the past 12 months (OR 4.40; 95% CI 3.56 to 5.44 p<0.001). 20 The association between paracetamol intake and those conditions may be due to the depletion of glutathione, a key antioxidant of the airways, as proposed by Cheelo et al 21 On the other hand, associations between asthma outcomes in children and secondhand smoking have been described in the literature with exposures associated…”
Section: Resultsmentioning
confidence: 99%
“…These results agree with what has been published in a recent study carried out in children in Angola, where the ISAAC study was used as a reference and reported that asthma symptoms were significantly associated with paracetamol use (OR 3.94; 95% CI 2.29 to 6.81 p<0.001), antibiotic uptake in the first year of life (OR 2.54; 95% CI 1.97 to 3.29 p<0.001), allergic rhinitis symptoms (OR 8.74; 95% CI 7.06 to 10.82 p<0.001) and itchy rash in the past 12 months (OR 4.40; 95% CI 3.56 to 5.44 p<0.001). 20 The association between paracetamol intake and those conditions may be due to the depletion of glutathione, a key antioxidant of the airways, as proposed by Cheelo et al 21 On the other hand, associations between asthma outcomes in children and secondhand smoking have been described in the literature with exposures associated…”
Section: Resultsmentioning
confidence: 99%
“…The sample size to estimate a prevalence of at least 13% with 3% precision was calculated using OpenEpi (https://www.openepi.com/; accessed on 30 May 2017) from a population of 17,873 children aged 5-14 years in CISA HDSS-Dande. Estimates of prevalence were based on previous studies from Bengo, Luanda or elsewhere in Africa: intestinal helminths 32% [25], asthma 13% [26], allergic rhinitis 19% [27], atopic eczema 20% [26], and atopy 25% [28]. The estimated sample size of 471 was increased to 1000 based on a~50% response rate.…”
Section: Samplementioning
confidence: 99%
“…The few studies reported have suggested that current residence in urban areas is associated with a higher risk of asthma than rural residence (10,11). Other risk factors, similar to those in HICs, include maternal smoking (12,13), maternal history of asthma (14), childhood atopic sensitisation (11,15) and history of allergy (14,16). Previous reports suggest no association between biomass fuels and asthma risk (17,18), but increased asthma symptoms (18,19).…”
Section: Introductionmentioning
confidence: 99%