Prevalence of apraxia among patients with a first left hemisphere stroke in rehabilitation centres and nursing homes

Donkervoort, Mireille; Dekker, Joost; Ende, E. van den; Stehmann-Saris, J.C.; Deelman, B.G.

doi:10.1191/026921500668935800

Cited by 90 publications

(54 citation statements)

References 10 publications

(34 reference statements)

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“…As the supramarginal and angular gyri of the IPL seem to be involved in gesture processing to a similar extent (Goldenberg and Hagmann, 1997;Hermsdörfer et al, 2001;Goldenberg and Karnath, 2006;Dovern et al, 2011), we targeted the border zone between these two parts of the IPL for stimulation electrode placement in each subject (Fig. 2).…”

Section: Methodsmentioning

confidence: 99%

“…Many left-hemispheric stroke patients suffer from apraxia (Donkervoort et al, 2000), a disorder of motor cognition, which cannot solely be explained by elementary deficits of the sensorimotor system, verbal communication deficits, or lack of motivation (Goldenberg, 2008;Frey et al, 2011). Apraxia impairs activities of daily life and interferes with neurorehabilitation (Hanna-Pladdy et al, 2003;Pomeroy et al, 2011).…”

Section: Introductionmentioning

confidence: 99%

“…They are, for example, impaired in imitating and matching of meaningless hand gestures (Goldenberg, 1999). In healthy subjects, hand gesture matching leads to increased activity in the left inferior parietal lobe (IPL) (Hermsdörfer et al, 2001), a common lesion site in apraxia (Dovern et al, 2011).…”

Section: Introductionmentioning

confidence: 99%

“…To date, therapeutic options for apraxia remain scarce despite its significant impact upon neurorehabilitation (Pomeroy et al, 2011;Vanbellingen and Bohlhalter, 2011;Cantagallo et al, 2012;Dovern et al, 2012). Transcranial direct current stimulation (tDCS) is a promising tool for modulating disturbed network function and the amelioration of cognitive deficits after stroke (for neglect, see Sparing et al, 2009).…”

Section: Introductionmentioning

confidence: 99%

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Transcranial Direct Current Stimulation (tDCS) of Left Parietal Cortex Facilitates Gesture Processing in Healthy Subjects

et al. 2013

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Gesture processing deficits constitute a key symptom of apraxia, a disorder of motor cognition frequently observed after left-hemispheric stroke. The clinical relevance of apraxia stands in stark contrast to the paucity of therapeutic options available. Transcranial direct current stimulation (tDCS) is a promising tool for modulating disturbed network function after stroke. Here, we investigate the effect of parietal tDCS on gesture processing in healthy human subjects. Neuropsychological and imaging studies suggest that the imitation and matching of hand gestures involve the left inferior parietal lobe (IPL). Using neuronavigation based on cytoarchitectonically defined anatomical probability maps, tDCS was applied over left IPL-areas PF, PFm, or PG in healthy participants (n ϭ 26). Before and after tDCS, subjects performed a gesture matching task and a person discrimination task for control. Changes in error rates and reaction times were analyzed for the effects of anodal and cathodal tDCS (compared with sham tDCS). Matching of hand gestures was specifically facilitated by anodal tDCS applied over the cytoarchitectonically defined IPL-area PFm, whereas tDCS over IPL-areas PF and PG did not elucidate significant effects. Taking into account tDCS electrode size and the central position of area PFm within IPL, it can be assumed that the observed effect is rather the result of a combined stimulation of the supramarginal and angular gyrus than an isolated PFm stimulation. Our data confirm the pivotal role of the left IPL in gesture processing. Furthermore, anatomically guided tDCS of the left IPL may constitute a promising approach to neurorehabilitation of apraxic patients with gesture processing deficits.

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Section: Methodsmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Transcranial Direct Current Stimulation (tDCS) of Left Parietal Cortex Facilitates Gesture Processing in Healthy Subjects

et al. 2013

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“…Neuropsychological studies have indicated that lesions of the left posterior parietal cortex (PPC), mainly in the inferior parietal lobule (IPL) or supramarginal gyrus, including the anterior intraparietal cortex, as well as those of the inferior frontal gyrus cause ideomotor apraxia (IMA), which accompanies impaired tool-use pantomimes for both right and left hands (Heilman et al 1982;Donkervoort et al 2000;Haaland et al 2000;10 Buxbaum 2001;Goldenberg et al 2007). IMA is neither caused by deficits in basic motor or sensory processing nor by general cognitive impairments, but rather by deficits in more abstract or higher level of motor engram, independent of the hand used (Goldenberg 2009).…”

Section: Introductionmentioning

confidence: 99%

Hand-independent representation of tool-use pantomimes in the left anterior intraparietal cortex

Ogawa

Imai

2016

Exp Brain Res

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Previous neuropsychological studies of ideomotor apraxia (IMA) indicated impairments in pantomime actions for tool use for both right and left hands following lesions of parieto-premotor cortices in the left hemisphere. Using functional magnetic resonance imaging (fMRI) with multi-voxel pattern analysis (MVPA), we tested the hypothesis that 5 the left parieto-premotor cortices are involved in the storage or retrieval of hand-independent representation of tool use actions. In the fMRI scanner, one of three kinds of tools was displayed in pictures or letters, and the participants made pantomimes of the use of these tools using the right hand for the picture stimuli or with the left hand for the letters. We then used MVPA to classify which kind of tool the subjects were pantomiming. 10Whole-brain searchlight analysis revealed successful decoding using the activities largely in the contralateral primary sensorimotor region, ipsilateral cerebellum, and bilateral early visual area, which may reflect differences in low-level sensorimotor components for three types of pantomimes. Furthermore, a successful cross-classification between the right and left hands was possible using the activities of the left inferior parietal lobule (IPL) near the 15 junction of the anterior intraparietal sulcus. Our finding indicates that the left anterior intraparietal cortex plays an important role in the production of tool-use pantomimes in a hand-independent manner, and independent of stimuli modality.

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2011

Psychological Management of Stroke

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Prevalence of apraxia among patients with a first left hemisphere stroke in rehabilitation centres and nursing homes

Abstract: This study shows that approximately one-third of left hemisphere stroke patients has apraxia.

Cited by 90 publications

References 10 publications

Transcranial Direct Current Stimulation (tDCS) of Left Parietal Cortex Facilitates Gesture Processing in Healthy Subjects

Transcranial Direct Current Stimulation (tDCS) of Left Parietal Cortex Facilitates Gesture Processing in Healthy Subjects

Hand-independent representation of tool-use pantomimes in the left anterior intraparietal cortex

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