Prevalence of antibodies to the BK and JC papovaviruses in isolated populations

Candeias, J. A. N.; Baruzzi, Roberto Geraldo; Pripas, Sergio; Lunes, M.

doi:10.1590/s0034-89101977000400008

Cited by 11 publications

(2 citation statements)

References 7 publications

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“…In contrast, in isolated and unacculturated populations, as of Amerindians, the frequency of seropositives is much lower, in some tribes being zero [Brown et al, 1975;Candeias et al, 1977]. Among the Yanomama, in whom we first detected rogue cells, the frequency of positives was 29.5% in a sample of Indians with an estimated average age of about 20 years, whereas in a sample of young, urban Japanese, average age 23.9 ± 4.5 years, the frequency of positives was 62.0%.…”

Section: The Frequency and Geography Of Jcv And Bkv Infectionmentioning

confidence: 95%

JC virus and its possible role in oncogenesis

Neel

1999

Am. J. Med. Genet.

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Section: The Frequency and Geography Of Jcv And Bkv Infectionmentioning

confidence: 95%

JC virus and its possible role in oncogenesis

Neel

1999

Am. J. Med. Genet.

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“…Numerous studies have shown that in urbanized, industrialized populations, significant hemagglutination antibody titers to JCV and BKV (titers ജ1/40) are observed in some 80% of all adults [reviewed in Walker and Frisque, 1986]. In contrast, in isolated and unacculturated populations, as of Amerindians, the frequency of seropositives is much lower, in some tribes being zero [Brown et al, 1975;Candeias et al, 1977]. Among the Yanomama, in whom we first detected rogue cells, the frequency of positives was 29.5% in a sample of Indians with an estimated average age of about 20 years, whereas in a sample of young, urban Japanese, average age 23.9 ± 4.5 years, the frequency of positives was 62.0%.…”

Section: The Frequency and Geography Of Jcv And Bkv Infectionmentioning

confidence: 99%

JC virus and its possible role in oncogenesis

Neel

1999

Am. J. Med. Genet.

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Discovery and Epidemiology of the Human Polyomaviruses BK Virus (BKV) and JC Virus (JCV)

Knowles¹

Advances in Experimental Medicine and Biology

277

208

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Although discovered over thirty years ago, many aspects of the epidemiology of BKV and JCV in the general population, such as the source of infectious virus and the mode of transmission, are still unknown. Primary infection with both BKV and JCV is usually asymptomatic, and so age seroprevalence studies have been used to indicate infection. BKV commonly infects young children in all parts of the world, with the exception of a few very isolated communities, adult seroprevalence rates of 65-90% being reached by the age of ten years. In contrast, the pattern of JCV infection appears to vary between populations; in some anti-JCV antibody is acquired early as for BKV, but in others anti-JCV antibody prevalence continues to rise throughout life. This indicates that the two viruses are probably transmitted independently and by different routes. Whilst BKV DNA is found infrequently in the urine of healthy adults, JCV viruria occurs universally, increasing with age, with adult prevalence rates often between 20% and 60%. Four antigenic subtypes have been described for BKV and eight genotypes are currently recognized for JCV. The latter have been used to trace population movements and to reconstruct the population history in various communities.

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Prevalence of antibodies to the BK and JC papovaviruses in isolated populations

Cited by 11 publications

References 7 publications

JC virus and its possible role in oncogenesis

JC virus and its possible role in oncogenesis

JC virus and its possible role in oncogenesis

Discovery and Epidemiology of the Human Polyomaviruses BK Virus (BKV) and JC Virus (JCV)

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