Prevalence of Antibiotic Resistance in Escherichia coli from the Fecal Flora of Humans in a Rural Area of Songkhla Province

Prasertsiriphong, Salisa; Chootong, Rattanaporn; Jamulitrat, Silom; Phengmak, Manthana

doi:10.31584/jhsmr.201967

Cited by 2 publications

(1 citation statement)

References 20 publications

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“…A report from the Ministry of Public Health in Thailand said that the five most common bacterial species involved in antibiotic resistance were Escherichia coli (E. coli), Klebsiella pneumoniae (K. pneumoniae), Acinetobacter baumannii (A. baumannii), Pseudomonas aeruginosa (P. aeruginosa) and methicillin-resistant Staphylococcus aureus (MRSA) [ 5 ]. A study in southern region of Thailand was reported that the resistance rate for amoxicillin, doxycycline and TMP-SMX were 53.3, 51.3, and 24.0%, respectively [ 22 ]. A community study in Tanzania [ 23 ] found that Escherichia coli strains were mostly present in infections and antibiotic resistance.…”

Section: Discussionmentioning

confidence: 99%

Antibiotic resistance among the Lahu hill tribe people, northern Thailand: a cross-sectional study

2021

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Background Antibiotic resistance is often reported and great concerned as one of public health problems especially people living with poverty in developing countries including Thailand. The hill tribe people is defined as vulnerable population for antibiotic resistance in Thailand due to poor economic and education status particularly the Lahu people who is the second greatest group of the hill tribe people in Thailand. The study aimed to estimate the prevalence, factors associated with, and typing major species of bacteria with antibiotic drugs resistance among the Lahu hill tribe people in northern Thailand. Methods A cross-sectional study was conducted to gather the information from the participants. A validated questionnaire was used for data collection. Participants who presented an illness related to infectious diseases were eligible to participate the study and were asked to obtain specific specimen; sputum, urine or stool. Antibiotic susceptibility was tested by Kirbey Bauer’s disc diffusion test. Chi-square and logistic regression were used to detect the associations between variables at the significant level of α = 0.05. Results A total of 240 participants were recruited into the study. The majority had urinary tract infection (67.9%) with two major pathogenic species of the infection; Escherichia coli (12.8%), and Enterobacter cloacae (8.0%). The prevalence of antibiotic resistance was 16.0%. Escherichia coli and Klebsiella pneumoniae species were found to have multidrug resistance that was greater than that of other species, while ampicillin was found to have the greatest drug resistance. It was found that those who had poor knowledge of antibiotic use had a 2.56-fold greater chance (95% CI = 1.09–5.32) of having antibiotic resistance than did those who had good knowledge of antibiotic use, and those who had poor antibiotic use behaviors had a 1.79-fold greater chance (95% CI = 1.06–4.80) of having antibiotic resistance than did those who had good antibiotic use behaviors. Conclusion Effective public health interventions are urgently needed to reduce antibiotic drug resistance among the Lahu people by improving their knowledge and skills regarding the proper use of antibiotics and eventually minimizing antibiotic resistance. Moreover, health care professionals should strictly follow the standard guideline to prescribe antibiotics.

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Section: Discussionmentioning

confidence: 99%

Antibiotic resistance among the Lahu hill tribe people, northern Thailand: a cross-sectional study

2021

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Scenario of Antibiotic Resistance in Developing Countries

Hassan¹

2021

Antimicrobial Resistance - A One Health Perspective

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Antibiotic resistance is an emerging global concern. It is an increasing threat to public health sectors throughout the world. This devastating problem has drawn attention to researchers and stakeholders after a substantial economic loss for decades resulting from the ineffectiveness of antibiotics to cure infectious diseases in humans and animals. The spectrum of antibiotic resistance varies between developed and developing countries due to having variations in treatment approaches. Antibiotic therapy in the developed countries is usually rational and targeted to specific bacteria, whereas in the developing countries, most of the cases, the use of antibiotics is indiscriminate to the disease etiology. In developing countries, many people are not aware of using antimicrobials. They usually get suggestions from drug sellers and quacks who do not have the authorization to prescribe a drug. If registered doctors and veterinarians are asked to prescribe, then dose, course, and withdrawal period might be maintained adequately. Antibiotic resistance transmission mechanisms between agricultural production systems, environment, and humans in developing countries are very complex. Recent research makes a window to find out the global situation of antibiotic use and resistance pattern. The antibiotic resistance scenario in selected developing countries has been summarized in this chapter based on published literature (Table 1). This chapter describes the judicial use of antibiotics and discussed maintaining proper antibiotic dose, course, drug withdrawal period, especially on food-producing animals. The book contains a few recommendations, suggested by the national multi-sectoral surveillance committee to avoid antibiotic resistance organisms in livestock and humans in the developing countries.

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Prevalence of Antibiotic Resistance in Escherichia coli from the Fecal Flora of Humans in a Rural Area of Songkhla Province

Cited by 2 publications

References 20 publications

Antibiotic resistance among the Lahu hill tribe people, northern Thailand: a cross-sectional study

Antibiotic resistance among the Lahu hill tribe people, northern Thailand: a cross-sectional study

Scenario of Antibiotic Resistance in Developing Countries

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