Prevalence of anti‐parvovirus B19 IgG and IgM and parvovirus B19 viremia in pregnant women in an urban area of Northern Italy

Massimo, De Paschale; Claudia, Pavia; Cerulli, Teresa; Cagnin, Debora; Manco, Maria Teresa; Belvisi, Laura; Paganin, Alessia; Laura, Pogliani; Elena, Ceriani; Porta, Alessandro; Luciana, Parola; Paola, Mirri; Bianca, Osnaghi; Laura, Vismara; Pierangelo, Clerici

doi:10.1002/jmv.27963

Cited by 4 publications

(2 citation statements)

References 31 publications

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“…(69.5%) samples were IgG-positive, (1.1%) IgMpositive. Of the 21 IgM-positive women, (1%) were confirmed positive also by Polymerase chain reaction [15].…”

Section: Discussionmentioning

confidence: 98%

Seroprevalence study of Parvovirus B19 among women with miscarriage in Mosul city

Nawfal Buraa,

Baqer Al-Obaidi,

Ali Hussein

2023

DJM

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Background: Miscarriage and stillbirth are among the most common pregnancy complications, and could be caused by several factors, among these factors are viral infections some of them are obvious teratogenic and others are associated with fetal defects like severe anemia in the case of Parvovirus B19 which could be transmitted vertically causing fetal infection and miscarriage or stillbirth. Objective: To investigate the seroprevalence of Parvovirus B19 among women with miscarriage and stillbirth and compare them with normal pregnant women in the city of Mosul-Iraq. Patients and Methods: A case-control study conducted on pregnant aged 16-45 years with miscarriage and stillbirth admitted to Al-Khansa Teaching Hospital in Mousl city. The samples were collected during the period from November 2022 and January 2023 from 160 from pregnant women, 80 of them had miscarriage or stillbirth, and the other 80 had normal uneventfull pregnancy (control). Serum samples were subjected for ELISA Study of anti-B19V IgG and IgM antibodies. Results: This study showed that the seroprevalence rate of anti-B19V IgG among pregnant women was about 23% (37 out of 160), subdivided into (40%) 32 out of 80 patients, and (6.2%) 5 out of 80 controls had positive anti-B19V IgG antibody which is significantly different. And IgM seroprevalence was about 22% (35 out of 160), in which (38.8%) 31 out of 80 patients, and (5%) 4 out of 80 controls had positive anti-B19V IgM antibody. Both anti-B19V IgG and IgM were higher among patients who had stillbirth than those who had miscarriage both qualitatively and quantitatively. On the other hand, there is a highly significant association of anti-B19V IgM positivity with maternal anemia. Conclusion: The study found high association between B19V and miscarriage or stillbirth as compared to normal pregnancy, and this was more common among patients who had stillbirth than those who had miscarriage, with obvious association with maternal anemia, all of the above is among pregnant women from Mosul City in Iraq. Keywords: miscarriage , stilbirth

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“…(69.5%) samples were IgG-positive, (1.1%) IgMpositive. Of the 21 IgM-positive women, (1%) were confirmed positive also by Polymerase chain reaction [15].…”

Section: Discussionmentioning

confidence: 98%

Seroprevalence study of Parvovirus B19 among women with miscarriage in Mosul city

Nawfal Buraa,

Baqer Al-Obaidi,

Ali Hussein

2023

DJM

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“…When viral myocarditis develops, cardiac rhythm disturbances occur, which may lead to fetal cardiac arrest and death [52]. The main clinical manifestation of congenital PVI is thought to be nonimmune fetal hydrocele, which develops in 80% of cases in the second trimester of pregnancy [53,54]. Congenital PVI may also manifest with hepatosplenomegaly, sickle cell anemia, developmental delay and other pathological conditions [50].…”

Section: Frequency Of Detection Of Pvi Markers In Pregnant Women and ...mentioning

confidence: 99%

Parvovirus B19 infection: characteristics of population immunity in the world

Nikishov,

Kuzin,

Lavrentieva

et al. 2024

Journal of microbiology, epidemiology and immunobiology

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Parvovirus B19 infection (PVI) is one of the relatively new problems in infectology, data on the study of its prevalence in our country began to appear only at the beginning of the twenty-first century. The article presents the results of an analysis of studies from available literature sources highlighting the prevalence of PVI markers at the population level among different social groups of the population at the present stage. The clinical manifestations of PVI are diverse, which requires differential diagnosis, both with exanthemic infectious diseases and with non-infectious pathology. Due to the peculiarity of PVI pathogenesis, it is relevant for various socially significant populations, primarily patients with exanthemic manifestations of various diseases, persons from among blood donors, pregnant women and women planning pregnancy. Furthermore, unlike most countries, our country does not have a system for PVI detecting and reporting in the system of state sanitary and epidemiological supervision, which makes it difficult to conduct research on this topic.

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