Prevalence of Anemia: a study on inpatients records with chronic kidney disease at Prince Mutaib Hospital, Al-Jouf Province, Saudi Arabia

Khalifa, Athar M.; Almoallem, Rahaf; Alruwaili, Sultanah; Mohammed, Ahlam T.; Alanazi, Saba

doi:10.24911/ijmdc.51-1574930119

Cited by 4 publications

(3 citation statements)

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“…According to the table indicated (1-1). That's agreement with previous studies [12]. The results of the current study showed in the age group (40-60) that there was a decrease significant at (P< 0.05) in HB and PCV for non-hemodialysis patients compared with control According to the table indicated (1).…”

Section: Parameter Of Bloodsupporting

confidence: 92%

Investigation of some Heavy Metals on Parameter of Blood and Oxidative Enzyme in CKD in Iraq-Al-Qadisiyah

Aljashamy,

Hussein

2023

IOP Conf. Ser.: Earth Environ. Sci.

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Sampling Blood collected for patients with renal failure of the dialysis group and the non-dialysis group for randomly for (40-60) age. And conduct tests CBC. The oxidation enzymes and some of the sample heavy metal (Ai, Cd, Cr, Pb and As) after digestion and measured in atomic spectrophotometer the result show They found a clear relationship between kidney failure and the effect of heavy metals. Where it affected the blood rate and the number of white blood cells and oxidation enzymes. Where were the values after conducting the tests (12.8 ± 0.45) (9.57 ± 0.62) (9.43 ± 0.47) respectively for control, hemodialysis and non-hemodialysis for Hp. Tests for WBCs (7.8 ± 0.32) (8.07 ± 0.75) (8.37 ± 0.50) respectively for control, hemodialysis and non-hemodialysis. The results of the current study showed in the age group (40_60) that there was a decrease in significant at (P< 0.05) in SOD, GSH and CAT for hemodialysis patients compared with control (0.336±0.035 Mg\dl), (0.4086±0.0041 Mg\dl) and (0.191±0.0051 Mg\dl) Consecutively, according to the table indicated (1-2) and That’s agreement with previous studies. The results of the current study showed in the age group (40_60) that there was a decrease in significant at (P< 0.05) in SOD, GSH and CAT for non-hemodialysis patients compared with control (0.748±0.071 Mg\dl), (0.838±0.019Mg\dl) and (0.335±0.0023 Mg\dl) Consecutively, according to the table indicated (1-2) and That’s agreement with previous studies

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Section: Parameter Of Bloodsupporting

confidence: 92%

Investigation of some Heavy Metals on Parameter of Blood and Oxidative Enzyme in CKD in Iraq-Al-Qadisiyah

Aljashamy,

Hussein

2023

IOP Conf. Ser.: Earth Environ. Sci.

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“…In advanced chronic kidney disease folate metabolism must be considered due to serious homeostatic disorders altering cellular functions. In end stage kidney disease, an insignificant proportion of patients, diminished serum folate concentration was shown due to malnutrition, low uptake and incorporation of 5-methyl-THF into cellular cycles [ 191 , 192 ].…”

Section: The Main Clinical Syndromes Of Folate Deficiencymentioning

confidence: 99%

The Concept of Folic Acid in Health and Disease

et al. 2021

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Folates have a pterine core structure and high metabolic activity due to their ability to accept electrons and react with O-, S-, N-, C-bounds. Folates play a role as cofactors in essential one-carbon pathways donating methyl-groups to choline phospholipids, creatine, epinephrine, DNA. Compounds similar to folates are ubiquitous and have been found in different animals, plants, and microorganisms. Folates enter the body from the diet and are also synthesized by intestinal bacteria with consequent adsorption from the colon. Three types of folate and antifolate cellular transporters have been found, differing in tissue localization, substrate affinity, type of transferring, and optimal pH for function. Laboratory criteria of folate deficiency are accepted by WHO. Severe folate deficiencies, manifesting in early life, are seen in hereditary folate malabsorption and cerebral folate deficiency. Acquired folate deficiency is quite common and is associated with poor diet and malabsorption, alcohol consumption, obesity, and kidney failure. Given the observational data that folates have a protective effect against neural tube defects, ischemic events, and cancer, food folic acid fortification was introduced in many countries. However, high physiological folate concentrations and folate overload may increase the risk of impaired brain development in embryogenesis and possess a growth advantage for precancerous altered cells.

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“…Anemia is inevitable and common complication in chronic kidney disease [3]. The World health organization (WHO) de nes anemia as "hemoglobin concentration < 13g/dl in men and < 12g/dl in women of child-bearing age".…”

Section: Introductionmentioning

confidence: 99%

Prevalence and management of anemia and impact of treatment burden on health-related quality of life in CKD and dialysis patients

Hussain

Khan

Chinnam

et al. 2023

Preprint

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Background Anemia management in chronic kidney disease (CKD) is a significant challenge to healthcare professionals worldwide. The extensive management of CKD and its complications are directly linked with a substantial treatment burden and it impacts the quality of life. This study aimed to assess the prevalence and management of anemia and to evaluate the treatment burden and its impact on the quality of life in CKD and Dialysis patients.Methodology A multicenter prospective observational study was conducted in three different hospitals. Initially, 170 patients were recruited in the study with prior consent taken from them. A face-to-face interview was conducted, and a data collection form was distributed among study participants.Results The prevalence of anemia among CKD (stage 3–5) and dialysis patients was 78.7% and 94.7% respectively at baseline. Dialysis patients used more erythropoietin stimulating agents (ESAs) i.e. 38.6% at baseline and 40.8% at month 6 compared to non-dialysis CKD patients. Dialysis patients had a higher treatment burden compared to CKD at baseline (77.4 ± 10.6 vs 59.3 ± 13.3) and at month 6 visit (79.3 ± 11.1 vs 59.1 ± 14.5). The Multiple regression analysis showed that treatment burden had a significant association with age, duration of disease and presence of comorbidity at baseline. There was a strong negative correlation between overall treatment burden and quality of life.Conclusion Anemia was prevalent and its management was suboptimal in the current study. The overall treatment burden score was high in dialysis patients and negatively affects the quality of life.

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Prevalence of Anemia: a study on inpatients records with chronic kidney disease at Prince Mutaib Hospital, Al-Jouf Province, Saudi Arabia

Cited by 4 publications

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Investigation of some Heavy Metals on Parameter of Blood and Oxidative Enzyme in CKD in Iraq-Al-Qadisiyah

Investigation of some Heavy Metals on Parameter of Blood and Oxidative Enzyme in CKD in Iraq-Al-Qadisiyah

The Concept of Folic Acid in Health and Disease

Prevalence and management of anemia and impact of treatment burden on health-related quality of life in CKD and dialysis patients

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Prevalence of Anemia: a study on inpatients records with chronic kidney disease at Prince Mutaib Hospital, Al-Jouf Province, Saudi Arabia

Cited by 4 publications

References 0 publications

Investigation of some Heavy Metals on Parameter of Blood and Oxidative Enzyme in CKD in Iraq-Al-Qadisiyah

Investigation of some Heavy Metals on Parameter of Blood and Oxidative Enzyme in CKD in Iraq-Al-Qadisiyah

The Concept of Folic Acid in Health and Disease

Prevalence and management of anemia and impact of treatment burden on health-related quality of life in CKD and dialysis patients

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Product

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Prevalence of Anemia: a study on inpatients records with chronic kidney disease at Prince Mutaib Hospital, Al-Jouf Province, Saudi Arabia