Prevalence of and Risks for Cervical Human Papillomavirus Infection and Squamous Intraepithelial Lesions in Adolescent Girls

Moscicki, Anna‐Barbara; Ellenberg, Jonas H.; Vermund, Sten H.; Holland, Christie A.; Darragh, Teresa M.; Crowley-Nowick, Peggy A.; Levin, Linda; Wilson, Craig M.

doi:10.1001/archpedi.154.2.127

Cited by 130 publications

(70 citation statements)

References 32 publications

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“…Moscicki et al found prevalence rates of 54.5% for all genital HPV types and 29.1% for HR HPV types in a cross-sectional study of adolescent females [10]. The youngest women in a longitudinal study of college-aged women by Ho et al had the highest prevalence of HPV infection.…”

Section: Discussionmentioning

confidence: 96%

A Longitudinal Study of Genital Human Papillomavirus Infection in a Cohort of Closely Followed Adolescent Women

et al. 2005

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Section: Discussionmentioning

confidence: 96%

A Longitudinal Study of Genital Human Papillomavirus Infection in a Cohort of Closely Followed Adolescent Women

et al. 2005

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“…Evidences showed that, immunosuppression and low CD4 counts caused by HIV infection predisposes women living with HIV infection at an increased risk for cervical cancer and the development of squamous intraepithelial lesions [5][6][7][8][9]. Cervical cancer is about 8 times more common in HIV infected women than none infected ones [5].…”

Section: Introductionmentioning

confidence: 99%

Comprehensive Knowledge and Uptake of Cervical Cancer Screening is Low Among Women Living with HIV/AIDS in Northwest Ethiopia

Mersha

2017

Value in Health

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Background: In Ethiopia, cervical cancer is ranked as the second most common type of cancer in women and it is about 8 times more common in HIV infected women. However, data on knowledge of HIV infected women regarding cervical cancer and acceptability of screening is scarce in Ethiopia. Hence, the present study was aimed at assessing the level of knowledge of about cervical cancer and uptake of screening among HIV infected women in Gondar, northwest Ethiopia. Methods: A cross sectional, questionnaire based survey was conducted on 302 HIV infected women attending the outpatient clinic of University of Gondar referral and teaching hospital from March 1 to 30, 2017. Descriptive statistics, univariate and multivariate logistic regression analysis were also performed to examine factors associated with uptake of cervical cancer screening service. Results: Overall, only 64 (21.2%) of respondent were knowledgeable about cervical cancer and screening and only 71 (23.5%) of respondents were ever screened in their life time. Age between 21 and 29 years old (AOR = 2.78, 95% CI = 1. 71-7.29), perceived susceptibility to develop cervical cancer (AOR =2.85, 95% CI = 1.89-6.16) and comprehensive knowledge of cervical cancer (AOR = 3.02, 95% CI = 2.31-7.15) were found to be strong predictors of cervical cancer screening service uptake. Conclusion: The knowledge and uptake of cervical cancer screening among HIV infected women was found to be very poor. Taking into consideration the heightened importance of comprehensive knowledge in boosting up the number of participants towards cervical cancer screening services, different stakeholders working on cancer and HIV/ AIDS should provide a customized health promotion intervention and awareness creation to HIV-infected women, along with improving accessibility of cervical cancer screening services in rural areas.

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“…Cervical cancer usually affects women of middle or older age, but it may be diagnosed in any reproductive-aged women especially those infected with HIV/AIDS which enhances HPV proliferation (Moscicki et al, 2000;Strickler et al, 2005).…”

Section: Introductionmentioning

confidence: 99%

Factors associated with management of cervical cancer patients at KCMC Hospital, Tanzania: a retrospective cross-sectional study

Mosha¹,

Mahande²,

Ahaz³

et al. 2009

Tanzania J Hlth Res

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Cervical cancer is an important public health problem among adult women worldwide. It is the second commonest malignancy in female worldwide and the leading malignancy among women in Tanzania. In most developing countries, cancer of the cervix tends to be diagnosed in its later stages when is less treatable. This study aimed at assessing factors associated with management of cervical cancer at KCMC Hospital in northern Tanzania. A purpose sampling was used to select a total of 200 patient records out of 374 with complete information. Median age of cervical cancer patients was 51 years (range 21-84 years) and 81.5% were either married or co-habiting. Stage of the cervical cancer (χ 2 = 28.63, p < 0.001) and age (χ 2 = 12.62, P<0.05) were significant predictors for patient's management plan, with 56% of cases seen at late cancer stage. Forty-seven percent of the cervical cancer patients were referred to Ocean Road Cancer Institute for radiotherapy and or chemotherapy. Patients discharged home for palliative care were 30% and 17% patients died at the hospital. Known HIV positive patients were significantly associated with death and terminal care seen at late stage than patients with unknown HIV sero-status (χ 2 = 20.16, P<0.001). In conclusion, most of cervical cancer patients at KCMC are seen at late stage necessitating referral for radiotherapy, chemotherapy or palliative care. This may reflect lack of cervical screening in order to early detect and treat pre-malignant disease stage.

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Prevalence of and Risks for Cervical Human Papillomavirus Infection and Squamous Intraepithelial Lesions in Adolescent Girls

Cited by 130 publications

References 32 publications

A Longitudinal Study of Genital Human Papillomavirus Infection in a Cohort of Closely Followed Adolescent Women

A Longitudinal Study of Genital Human Papillomavirus Infection in a Cohort of Closely Followed Adolescent Women

Comprehensive Knowledge and Uptake of Cervical Cancer Screening is Low Among Women Living with HIV/AIDS in Northwest Ethiopia

Factors associated with management of cervical cancer patients at KCMC Hospital, Tanzania: a retrospective cross-sectional study

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